9 Ways To Cut Your Risk of Alzheimer’s Disease

Only 40 years ago it was widely believed that if you lived long enough, you would eventually experience serious cognitive decline, particularly with respect to memory. The implication for cognition was that achieving an advanced age was effectively equivalent to becoming senile – a word that implies mental defects or a dementing (1) illness. Since then there has been a major shift away from the view of “aging as a disease” and towards the view of “aging as only a risk factor” for a number of neurological diseases.

A recent Lancet report, by 24 leading dementia researchers from around the world, zeroed in on nine of the best-known lifestyle factors that contribute to the illness and account for more than a third of dementia cases. Not smoking, doing exercise, keeping a healthy weight, treating high blood pressure and diabetes can all reduce the risk of dementia, as well as cardiovascular disease, and cancer. The researchers say they did not have enough data to include dietary factors or alcohol in their calculations but believe both could be important.

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Source: Lancet

The takeaway: 1 in three cases of dementia could be prevented if more people looked after their brain health throughout life.

Related Reading: 15 Ways To Stave Off Dementia

 


(1) Dementia is how we describe symptoms that impact memory and lead to a decline in cognitive performance, often in ways that disrupt daily living. There are different brain disorders that cause dementia, but Alzheimer’s is the most common, followed by cerebrovascular disease and Lewy bodies disease.

Weekly Neuroscience Update

optogenetics-living-brain-neurosciencenews.jpgA new optogenetic method called Optobow is helping researchers to discover specific and individual components of functional neural networks in the living brain. A Nature Communications report states this new method can help provide more detailed insights into both brain function and structure.

A new Translational Psychiatry report suggests physical exercise may help protect neurons and reduce symptoms of dementia in older people.

Researchers have developed a software tool that analyzes functional magnetic resonance imaging (fMRI) scans of patient brains and with 74% accuracy diagnoses schizophrenia. Moreover, the software’s algorithms were also able to reasonably estimate how bad the symptoms of the disease were in individual patients.

A new study reveals a drug currently used to treat dementia may be helpful in the treatment of traumatic brain injury.

Individual differences in the pattern of release of the hormone cortisol in response to a stressful experience reveal how stressed a person actually feels, suggests a study of healthy women published in The Journal of Neuroscience. This approach could help to better identify and treat individuals more susceptible to the negative feelings associated with the physiological stress response.

A new study has found that a gene variant, thought to be carried by nearly 25 percent of the population, increases the odds of developing depression.

Just as athletes cross-train to improve physical skills, those wanting to enhance cognitive skills can benefit from multiple ways of exercising the brain, according to a comprehensive new research.

A small patch of neurons fires in complex ways to encode movement of much of the body according to new research.

Using cryo-electron microscopy, researchers have been able to capture how glutamate opens glutamate receptor ion channels. The Nature study provides significant insight into how receptors can mediate brain function.

Finally this week, a team at the University of Wollongong, Australia, has used a 3D printer to create nerve cells found in the brain.

 

Weekly Neuroscience Update

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Thousands of branches and branchlets emanate from an astrocyte’s cell body, which is the dense portion in the middle of the image.

A new study published in Neuron challenges the idea that astrocytes across the brain are largely identical.

Researchers have identified a new protein, CIB2, that is key to helping the auditory system to turn soundwaves into meaningful brain signals. Mutations of this gene leave people unable to convert the soundwaves into signals that the brain can interpret, and are deaf.

The more regularly people report doing word puzzles such as crosswords, the better their brain function in later life, a large-scale online trial has found.

How short-term memories become long-term ones has frequently been explored by researchers. While a definitive answer remains elusive, scientists conclude that this transformation is best explained by a “temporal hierarchy” of “time windows” that collectively alter the state of the brain.

Greater muscle strength is associated with better cognitive function in ageing men and women, according to a new Finnish study.

Researchers at King’s College London have identified a molecular mechanism that allows neural connections to adapt as a result of experience. This adaptation fuels our ability for memory and learning.

Researchers have developed a concept called Empowerment to help robots and humans to work and live side-by-side safely and effectively.

A study of post-traumatic stress disorder (PTSD) has identified a new potential mechanism contributing to the biology of the disorder that may be targeted by future treatments.

A new study reveals those who die at 100 tend to suffer from fewer diseases than those who die at younger ages.

A new paper identifies 100 of the most cited neuroscience research papers. Of these papers, 78 focus on five topics. According to the authors of the paper, the most cited neuroscience research topics include the prefrontal cortex, neural connectivity, methodology, brain mapping and neurological disorders. The findings could have significant impact for future neuroscience studies.

Changes in the brain’s structure that could be the result of depression have been identified in a major scanning study.

The same mechanisms that quickly separate mixtures of oil and water are at play when controlling the organization in an unusual part of our DNA called heterochromatin, according to a new study.

New research has shown just how adaptive the brain can be, knowledge that could one day be applied to recovery from conditions such as stroke.

Changes in the orbitofrontal cortex and basolateral amygdala may help explain a person’s preference for uncertain outcomes, as well as a preference for order and certainty, a new study reports.

Finally this week, a small patch of neurons in the brain can encode the movements of many body parts, according to new research.

Weekly Neuroscience Update

synapses-visual-world-neurosciencenews.jpg

Our brain is especially good at perceiving lines and contours even if they do not actually exist, such as the blue triangle in the foreground of this optical illusion. The pattern of neuronal connections in the brain supports this ability.

Researchers have identified how our brains are so good at perceiving contours and edges. The study, published in Nature, reports neurons are most likely to connect if they react to edges that lie on a common axis and the structure of the world around us is mirrored in the pattern of synapses.

A new study reports bilingual people think about time differently depending on the language context they are estimating event duration.

The first large study to rigorously examine brain-training games using cognitive tests and brain imaging adds to evidence that they are not particularly good at training brains and appear to have no more effect on healthy brains than video games.

Scientists report that listening to something while looking in a different direction may slow reaction times and increase the effort for auditory attention.

The part of the brain that helps control emotion may be larger in people who develop post-traumatic stress disorder (PTSD) after brain injury compared to those with a brain injury without PTSD, according to a new study.

Researchers are investigating why certain language abilities are lost as a result of a traumatic brain injury, and how others can be regained.

A recently published study investigates time perception and temporal information processing in people with schizophrenia. It reveals the internal clock in schizophrenics does not necessarily run slower or faster than in healthy individuals, but rather it does not run at a consistent speed.

Finally, this week, using music to learn a physical task develops an important part of the brain, according to a new study.

 

Weekly Neuroscience Update

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Practicing paying attention can boost performance on a new task, and change the way the brain processes information, a new study says. This might explain why learning a new skill can start out feeling grueling, but eventually feels more natural — although right now, the study’s findings are limited to a simple pattern-recognition game.

A new study reports traumatic brain injury is associated with a higher risk of developing dementia in people of working age.

According to researchers, the ability to assess memory quality appears in children, and metamemory continues to improve beyond childhood into adolescence. The findings could provide new insights into effective learning methods and assist teachers to devise new educational strategies.

Researchers report harmful plaques associated with Alzheimer’s disease may build up in the brain as a result of high blood pressure and decreased cerebral blood flow.

A new paper may help answer some questions as to why some infants die suddenly. Looking at blood samples from infants who had died of SIDS, researchers discover 31% of the children had elevated levels of serotonin. The researchers concluded that abnormal serotonin metabolism could indicate an underlying vulnerability that increases SIDS risk.

Using musical cues to learn a physical task significantly develops an important part of the brain, according to a new study.

Poor sleep may be a sign that people who are otherwise healthy may be more at risk of developing Alzheimer’s disease later in life than people who do not have sleep problems, according to a study published in Neurology. Researchers have found a link between sleep disturbances and biological markers for Alzheimer’s disease found in the spinal fluid.

A new study reports that listening to something while looking in a different direction may slow reaction times and increase the effort for auditory attention.

Finally, this week, higher intelligence (IQ) in childhood is associated with a lower lifetime risk of major causes of death, including heart disease, stroke, smoking-related cancers, respiratory disease and dementia, finds a study published by The BMJ.

Weekly Neuroscience Update

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This latest research builds on the pioneering use of machine learning algorithms with brain imaging technology to “mind read.” The findings indicate that the mind’s building blocks for constructing complex thoughts are formed by the brain’s various sub-systems and are not word-based.  Image is credited to Carnegie Mellon University.

Researchers report they can use brain activation patterns to identify complex thoughts. Their findings suggest the building blocks for complex human thoughts are not word based, but formed by the brain’s sub systems. The study provides evidence that the neural dimensions of concept representation are universal across people and languages.

A new study considers how echolocation can benefit visually impaired people to navigate safely through the environment.

Neuroscientists have used a classic branch of maths in a totally new way to peer into the structure of our brains. What they’ve discovered is that the brain is full of multi-dimensional geometrical structures operating in as many as 11 dimensions.

People tend to change the pitch of their voice depending on who they are talking to, and how dominant they feel, a new study has found.

Researchers have identified a network of neurons that plays a vital role in learning vocalizations by aiding communication between motor and auditory regions of the brain.

A new study reinforces the idea that serotonin, a molecule associated with mood, directly contributes to the actions of cocaine.

A new report published by the National Academies of Sciences, Engineering, and Medicine shows evidence supporting three interventions for cognitive decline and dementia—cognitive training, blood pressure management for people with hypertension, and increased physical activity, which might slow down cognitive decline and the onset of dementia.

Therapies to change the bacteria in the gut, through diet, pro-and prebiotic supplements, faecal matter transplants or antibiotics, could treat autism.

Finally this week, researchers say a protein usually associated with the immune system could play a role in the development of neurological conditions such as epilepsy and schizophrenia.

 

Weekly Neuroscience Update

girl-1990347_960_720.jpgA new report reveals how the development of music is so closely tied to our own evolution.

Even a single bout of physical activity can have significant positive effects on people’s mood and cognitive functions, according to a new study in Brain Plasticity.

A new study reports on the complex brain connections employed during word retrieval.

New research provides an unprecedented level of resolution and insight into disturbances in cortical GABAergic microcircuits, which are thought to underlie cognitive impairments in schizophrenia.

A sign language study helps researchers better understand how the brain processes language.

Researchers say the goal of memory is not to transmit the most accurate information over time, but to optimize intelligent decision making by holding on to valuable information.

A new study reports microglia may play a role in a diverse array of neurodegenerative and psychiatric illnesses.

A new brain imaging study shows for the first time that brain inflammation is significantly elevated – more than 30 per cent higher – in people with obsessive-compulsive disorder (OCD) than in people without the condition.

A research team has studied two structurally-similar proteins in the adult brain and have found that they play distinct roles in the development of dementia. 

Neurons found to be abnormal in psychosis play an important role in our ability to distinguish between what is real and what is perceived, researchers say.

A new study sheds light on the neural mechanism behind why some people with autism are unable to make eye contact with others.

While researchers report the risk of developing psychosis from cannabis use is relatively small, those who use the drug and already suffer from schizophrenia may notice their condition worsen.

Finally this week, researchers have discovered a mechanism of glucose sensing by muscles that contribute to the regulation of blood sugar levels in the body.

Weekly Neuroscience Update

4121A56E00000578-4574260-image-a-57_1496767085907.jpgElectrically stimulating the dorsolateral prefrontal cortex can enhance our ability to ‘think outside the box’, a new study reports.

An international team of researchers has found, for the first time, seven risk genes for insomnia. With this finding the researchers have taken an important step towards the unravelling of the biological mechanisms that cause insomnia. In addition, the finding proves that insomnia is not, as is often claimed, a purely psychological condition.

Researchers have developed a neural network based AI system that can decode and predict what a person is seeing or imagining.

A new study reports artificial intelligence used by the military to help shoot down fighter planes can accurately predict treatment outcomes for people with bipolar disorder.

New research sheds light on how the brain codes navigation behaviour at larger scales.

The visual cortex, the human brain’s vision-processing center that was previously thought to mature and stabilize in the first few years of life, actually continues to develop until sometime in the late 30s or early 40s, a neuroscientist and her colleagues have found.

Clusters of a sticky protein — amyloid plaque — found in the brain signal mental decline years before symptoms appear, a new study finds.

According to researchers, brain signals in specific brain areas change during a lifespan in ways that could be vital for maintaining flexibility.

Two new studies shed light on how the brain encodes and recalls memories.

People with voice disorders may have a problem with correctly utilizing auditory feedback to control their voices.

A new study reveals the role the motor system plays in the perception of language. 

According to researchers, bilingual children perform better at voice recognition and processing than monolingual children.

Fascination with faces is nature, not nurture, suggests a new study of third-trimester fetuses.

Finally this week, the mystery of how human eyes compute the direction of moving light has been made clearer by scientists at The University of Queensland.

Weekly Neuroscience Update

memory-codes-neurosciencenews.jpgIn a pair of studies, scientists at the National Institutes of Health explored how the human brain stores and retrieves memories. One study suggests that the brain etches each memory into unique firing patterns of individual neurons. Meanwhile, the second study suggests that the brain replays memories faster than they are stored.

A machine learning algorithm shows that during sleep, the brain actively reprocesses information learned the previous day, strengthening the memory.

Scientists  have revealed how laughter releases endorphins in the human brain. The more opioid receptors the participants had in their brain, the more they laughed during the experiment.

Researchers believe they may have cracked the code for facial recognition in the primate brain.

Theta oscillations, a type of rhythmic electrical activity that waxes and wanes four to eight times per second, may play a fundamental role in processing scent in the human brain, according to a new study recently published in Neuron.

Researchers investigate how neurons work together to help us make decisions.

A new Finnish study has now demonstrated that seeing others in pain activates the same brain regions involved in firsthand pain, which suggests that a shared neuromolecular pathway processes both types of pain. Specifically, the researchers showed that the endogenous opioid system, but not the dopamine system, contributes to vicarious pain.

Finally this week, a new study could help explain how neurons achieve greater efficiency and reliability.

 

 

Weekly Neuroscience Update

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In a collaboration between Swedish and Italian researchers, the aim was to analyse how the brain interprets information from a virtual experience of touch, created by a finger prosthesis with artificial sensation. The result was – completely unexpectedly – a new method for measuring brain health.

Stroke patients who learned to use their minds to open and close a device fitted over their paralyzed hands gained some control over their hands, according to a new study.

As children age into adolescence and on into young adulthood, they show dramatic improvements in their ability to control impulses, stay organized, and make decisions. Those ‘executive functions’ of the brain are key factors in determining outcomes, including educational success, drug use, and psychiatric illness. Now, researchers have mapped the changes in the network organization of the brain that underlie those improvements in executive function.

Despite numerous claims, researchers discover transcranial direct current stimulation likely adds no meaningful benefit to cognitive training.

Neuropsychiatric symptoms, specifically sleep behavior and irritability, are linked to metabolic dysfunction on specialized positron emission tomography (PET) imaging and may be an early noncognitive symptom of Alzheimer’s dementia, according to results published in Neurology.

Individual neurons can learn not only single responses to a particular signal, but also a series of reactions at precisely timed intervals.

Researchers from the Radboud University in the Netherlands have observed the human brain’s ability to visually “predict” future events. By scanning the brains of students during an experiment, they saw this predictive imaging in action.

Vicsoelasticity in the hippocampus is associated with better performance on both memory and fitness tests, a new study reports.

The visual cortex, the human brain’s vision-processing centre that was previously thought to mature and stabilize in the first few years of life, actually continues to develop until sometime in the late 30s or early 40s, neuroscientists have found.

New Finnish research reveals how brain’s opioids modulate responses towards other people’s pain.

Finally this week, researches report memory isn’t a single entity and memory formation can be enhanced by different brain states.