How Do Drugs Affect The Brain?

Most people will take a pill, receive an injection, or otherwise take some kind of medicine during their lives. But most of us don’t know anything about how these substances actually work. How can various compounds impact the way we physically feel, think, and even behave? Sara Garofalo explains how some drugs can alter the communication between cells in the brai

Weekly Neuroscience Update

 

 

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Credit: Herz et. al./Brown University

new study provides the first direct evidence that within each person, smell sensitivity varies over the course of each day. The pattern, according to the data, tracks with the body’s internal day-night cycle, or circadian rhythm.

Researchers have revealed the neural signatures for explicit and implicit learning.

Neuroscientists have discovered precisely where and how to electrically stimulate the human brain to enhance people’s recollection of distinct memories. People with epilepsy who received low-current electrical pulses showed a significant improvement in their ability to recognize specific faces and ignore similar ones.

Adults likely do not develop ADHD, according to new research.

Researchers propose a new theory of memory formation, reporting memory storage does not rely on the strengthening of connection between memory cells, but on the pattern of connections that form within the first few minutes of an event.

A new Finnish study shows that individual circadian preference is associated with brain activity patterns during the night.

According to researchers, the size, shape and number of dendritic spines in the brain may determine whether a person develops Alzheimer’s disease.

Finally this week, migraine triggers can increase oxidative stress, a new study reports. Targeting oxidative stress may help to prevent migraines.

 

 

Weekly Neuroscience Update

forest-868715_960_720.jpgA neuroimaging study reveals city dwellers who live closer to forests were more likely to have healthier amygdala structure and were better able to deal with stressful situations.

New research has found that a specific combination of techniques will increase people’s chances of having lucid dreams, in which the dreamer is aware they’re dreaming while it’s still happening and can control the experience.

A new study reports women who are exposed to trauma and suffer post-traumatic stress are at an increased risk of developing Lupus.

When mental and physical tasks are put in direct competition, cognition tends to win out. Researchers suggest more energy is directed to the brain than the body, supporting the ‘selfish brain’ theory of evolution.

Researchers have revealed the neural signatures for explicit and implicit learning.

A delayed neurological response to processing the written word could be an indicator that a patient with mild memory problems is at an increased risk of developing Alzheimer’s disease, research led by the University of Birmingham has discovered.

A new study reveals MRI brain scans can help identify neurological changes associated with multiple sclerosis before symptoms appear in children.

Researchers have shown for the first time a comprehensive picture of cell diversity in the amygdala, a vital brain region involved in the regulation of emotions and social behavior, as well as in autism spectrum disorders, depression and other mental disorders. As part of the study, the team also reported on a new method for systematically linking the distinct types of brain cells to specific behavioral functions.

Using three different training models, researchers report mental training, mindfulness and meditation can induce structural brain plasticity and reduce social stress.

Most cases of autism appear to be associated with the appearance of new mutations that are not inherited from the child’s parents, researchers from the University of Washington School of Medicine report.

A new brain-imaging study published in The American Journal of Psychiatry suggests scientists may be able to predict how likely children are to develop depression. 

Researchers have developed a new assessment model that breaks emotional regulation into three different elements. The MAS assessment will provide clinicians a new way in which to diagnose mood and mental health disorders.

A new study reports transcranial magnetic stimulation of the prefrontal cortex improves a person’s ability to evaluate their performance during a working memory task.

Researchers at Salk Institute report astrocytes initiate communication between pairs of neurons during early development, inducing specific neural changes. Findings may have implications for neurodevelopmental disorders such as ASD and ADHD.

Researchers have discovered a cellular mechanism that may contribute to the breakdown of communication between neurons in Alzheimer’s disease.

 

 

Weekly Neuroscience Update

 

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A bidirectional brain-computer interface (BBCI) can both record signals from the brain and send information back to the brain through stimulation. Credit: Center for Sensorimotor Neural Engineering (CSNE).

 

Researchers are investigating advances in brain-computer interface technologies and considering the implications of linking our brains up to technology.

A new study published in the online journal Radiology suggested that disconnections in the areas of the brain, which are involved in attention and visual processing might lead to visual hallucinations in patients with Parkinson’s disease.

Researchers present a new theory about dreaming, suggesting dreams may be an accidental byproduct of our waking cognitive abilities.

Scientists have long deemed the ability to recognize faces innate for people and other primates — something our brains just know how to do immediately from birth. However, the findings of a new Harvard Medical School study published Sept. 4 in the journal Nature Neuroscience cast doubt on this longstanding view.

Genetic processes that allow cells to transform so they can mend damaged nerves have been identified by scientists.

For the first time, researchers have been able to see changes in the neural structures in specific areas of the brains of people who suffered severe abuse as children.

A new study reveals molecular details of what happens when axons are damaged or completely severed.

A researcher has discovered the molecule that stores long-term memories — it’s called calcium/calmodulin dependent protein kinase (CaMKII).

Finally, this week, how well we are able to complete simple and complex tasks depends upon the organization of subnetworks in the brain, a new study reports.

 

 

Weekly Neuroscience Update

dog-2751115_960_720.jpgThe tendency of dogs to seek contact with their owners is associated with genetic variations in sensitivity for the hormone oxytocin, according to a new study from Linköping University, Sweden.

A new study reveals schizophrenia is up to 79% hereditary.

Metacognition of a tactile working memory task has been demonstrated by researchers for the first time. Understanding this brain function might help in the development of new treatments for neuropsychiatric illnesses in the future.

Researchers have shed light on how motor signals help sharpen our ability to decipher complex sound flows.

Increased communication between distant brain regions helps older adults compensate for the negative aspects of ageing, reports a new study published this week in Human Brain Mapping.

Scientists report brain network organization changes can influence executive function in young adults.

A news study has found that brain functions in young men and women are changed by long-term alcohol use, but that these changes are significantly different in men and women.

Mindfulness and meditation can affect brain plasticity, resulting in the ability for adults to acquire new social skills, researchers report.

A new study has found that chronic tinnitus (ringing or buzzing in the ears) is associated with changes in certain networks in the brain, and furthermore, those changes cause the brain to stay more at attention and less at rest.

Finnish researchers have revealed how eating stimulates brain’s endogenous opioid system to signal pleasure and satiety.

Finally this week, sleep deprivation — typically administered in controlled, inpatient settings — rapidly reduces symptoms of depression in roughly half of depression patients, according to the first meta-analysis on the subject in nearly 30 years.

 

Weekly Neuroscience Update

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Researchers report people with poor sleep quality were less likely to experience symptoms of depression if they had higher activity in the ventral striatum.

A new study, published in the open-access journal Frontiers in Human Neuroscience, has uncovered a simple, measurable explanation that can determine your preference for one song over another.

Almost a quarter of girls and one-tenth of boys show signs of depression at age 14, say researchers from the University College London.

Excessive neurogenesis following brain injury may lead to neurological problems and cognitive decline researchers report. The findings challenge common assumptions that excessive brain cell growth following injury is advantageous.

Whether we are consciously aware of seeing a familiar face and object or not, our brains actively notice

A new study has investigated which neurons react to different vocal pitches, discerning between different voices and reacting to emphasis. The findings help us to understand how the brain gains meaning from the sound of speech.

A new report examines the effect stress can have on our bodies and general health.

Finnish researchers have revealed that exercise-induced endorphin release in the brain depends on the intensity of the exercise. Endorphin release induced by exercise may be an important mechanism which affects exercise motivation and maintenance of regular physical activity.

Researchers reveal people who report higher levels of moral reasoning show increased activity in brain areas associated with reward. 

Finally this week, for most people, laughter is highly contagious. But researchers reporting in Current Biology on September 28 have new evidence to show that boys at risk of developing psychopathy when they become adults don’t have that same urge.

 

Weekly Neuroscience Update

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Scientists have developed a virtual reality computer game as part of the world’s biggest dementia research experiment. It is designed to test one of the first things to go with dementia – the ability to navigate.

Researchers have developed a robotic system that allows them to focus in on specific neurons in the brain. The technology could help answer questions such as how neurons interact with each other as we recall a memory.

Benzodiazepines—the family of popular sedatives that includes Valium and Xanaxseem to bring about structural changes in the brain, according to a European study running in the August edition of Psychiatry Neuroimaging.

Researchers report people who report higher levels of moral reasoning show increased activity in brain areas associated with reward. The study may improve understanding as to why some people are more likely to engage in prosocial behaviors.

Tinnitus, a chronic ringing or buzzing in the ears, has eluded medical treatment and scientific understanding. A new study found that chronic tinnitus is associated with changes in certain networks in the brain, and furthermore, those changes cause the brain to stay more at attention and less at rest.

Researchers have identified a specific area of the brain responsible for auditory verbal hallucinations in people with schizophrenia. The researchers were able to control the hallucinations with the help of transcranial magnetic stimulation.

Finally this week, a new study, published in the open-access journal Frontiers in Human Neuroscience, shows that older people who routinely partake in physical exercise can reverse the signs of aging in the brain, and dancing has the most profound effect.

 

Weekly Neuroscience Update

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Getty Images

People who played action video games that involve first-person shooters experienced shrinkage in a brain region called the hippocampus, according to a study published in Molecular Psychiatry. That part of the brain is associated with spatial navigation, stress regulation and memory. Playing Super Mario games, in which the plumber strives to rescue a princess, had the opposite effect on the hippocampus, causing growth in it.

Researchers have revealed a helpful strategy to help those with cognitive problems to improve their memory.

The part of the brain that helps control emotion may be larger in people who develop post-traumatic stress disorder (PTSD) after brain injury compared to those with a brain injury without PTSD, according to a new study.

A new study reports cognitive abilities mutually assist each other during development. This results in improved cognitive skills and general intelligence over time.

A sleeping brain can form fresh memories, according to a team of neuroscientists. The researchers played complex sounds to people while they were sleeping, and afterward the sleepers could recognize those sounds when they were awake.

Researchers report social norms together with increasing oxytocin can counter xenophobia by enhancing altruistic behaviors.

A new Johns Hopkins University study adds further evidence to the link between serotonin and dementia. According to researchers, lower serotonin levels may play a key role in memory decline and drive the progression of Alzheimer’s.

Researchers have devised a new odor identification test that could help doctors predict those at risk of Alzheimer’s and track the progression of the disease.

Finally this week, a new study reveals a neurobiological reason behind why we feel happy when we are being generous. Researchers discovered the connectivity between the temporal parietal junction and ventral striatum, an area of the brain associated with happiness, was enhanced in people who committed to generosity.

 

Weekly Neuroscience Update

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Brain scans from a 38-year-old, left, and a 73-year-old. 

Researchers are embarking on a new study to answer how some people are able to stay sharper than others as they age.

Neurons in the brain that produce the pleasure-signaling neurotransmitter dopamine also directly control the brain’s circadian center, or “body clock” – the area that regulates eating cycles, metabolism and waking/resting cycles – a key link that possibly affects the body’s ability to adapt to jet lag and rotating shift work, a new study has demonstrated.

A molecule produced by insulating glial cells facilitates the functional wiring of brain cells involved in motor coordination.

Using the latest MRI scanning procedures, a team of researchers has shown how certain disorders of the hippocampus can initiate a drug resistant epilepsy. The team has discovered biomarkers that – if used for screening – could massively improve treatment options for epilepsy. The researchers have published their results in the online journal eLife.

A new study reveals the role circular RNA plays in brain function, including synaptic transmission and sensorimotor gating.

Depression has been shown to alter the structure of the brain’s white matter, which contains the circuitry that allows brain cells to communicate with each other, and which underpins brain function.

According to a new Nature study, in order for our taste system to work, the connection between neurons and taste bud cells have to rewire correctly each time.

A new optogenetic method called Optobow is helping researchers to discover specific and individual components of functional neural networks in the living brain. A Nature Communications report states this new method can help provide more detailed insights into both brain function and structure.

A neuroimaging study reveals people who report widespread pain have increased gray matter and functional connectivity in sensory and motor areas of the brain.

Finally this week, a large scale SPECT imaging study reveals women’s brains are significantly more active in more regions than males, including the prefronal cortex and limbic areas. Visual and areas associated with coordination were more active in males, researchers noted.