Weekly Neuroscience Update

 

A new study reveals a high fructose diet could contribute to bipolar disorder, ADHD, and behavioral aggression.

In Alzheimer’s disease, impaired blood flow to brain regions coincides with tau protein buildup. This relationship strengthens as cognition declines, according to new research published in Journal of Neuroscience.

A new lab test can accurately pinpoint and analyze the deadliest cells in the most common and aggressive brain cancer in adults.

A greater density of cells in a key reward center of the brain is associated with obesity in children and predicts future weight gain, a new study finds.

A team of researchers has found that an amino acid produced by the brain could play a crucial role in preventing a type of epileptic seizure.

The characteristics of language structure and writing system may explain why some bilingual people are dyslexic in English, but not in their other proficient language.

Finally this week,  a study of four drugs to combat chronic neuropathic pain finds Nortriptyline has the highest efficacious percentage and lowest quit rate.

 

Weekly Neuroscience Update

Researchers used diffusion tensor imaging, which indicates the directionality of water diffusion in the brain, to examine how white matter connections lose integrity. These frontostriatal tracts are shown moving anterior to posterior (green), left to right (red) and superior to inferior (blue). Image is credited to the researchers.

As the human brain ages, the neural circuits that allow its different parts to communicate with each other gradually wear down, even in healthy adults.

Genetic risk score for bipolar disorder is associated with an increased risk of developing bipolar symptoms. The genetic risk factor for schizophrenia is linked to an increased risk of those with depression developing psychosis.

A new study into the causes of sensorimotor impairments prevalent among autistic people could pave the way for better treatment and management in the future, say psychologists.

New research details how the complex set of molecular and fluid dynamics that comprise the glymphatic system – the brain’s unique process of waste removal – are synchronized with the master internal clock that regulates the sleep-wake cycle. 

Future technology may be able to monitor and modify the brain to produce enhanced team performance, while increasing the efficiency and accuracy of decisions.

Parkinson’s disease can be divided into two variants that start in different places in the body. For some, the neurodegenerative disease starts in the intestines and spreads to the brain. In others, the disease begins in the brain and spreads to the intestines and other organs.

New research released from the University of Colorado Anschutz Medical Campus proposes that Alzheimer’s disease may be driven by the overactivation of fructose made in the brain.

Anticholinergic medications, commonly used for conditions including allergies, high blood pressure, Parkinson’s disease, and motion sickness, have been linked to an increased risk of cognitive decline and memory problems, especially in those with genetic risk factors for Alzheimer’s disease.

Finally this week, a new study links brain structure to color perceptual function. Microscopy revealed ‘hue maps,’ or color palettes, in the brain that are spectrally organized arrangements of hue responses.

 

 

Weekly Neuroscience Update

 

A new study identifies the neural markers of beat synchronization in the brain and sheds light on how auditory perception and motor processes work together.

Current sleep patterns could help determine your risk of developing Alzheimer’s disease as you age. People who experience more fragmented sleep and less non-REM slow-wave sleep are more likely to have increased levels of amyloid-beta.

An international research team reports that problems in spatial navigation can also be detected in people with a genetic risk for Alzheimer’s. 

A new study demonstrates that a technology developed at the University of Central Florida could serve as a more reliable clinically-based model of amyotrophic lateral sclerosis (ALS) and a better screening tool for novel therapies than currently use preclinical models.

New long-term brain monitoring technologies that can continuously record brain activity could help improve the treatment and management of epilepsy.

Scientists have developed a new theory as to how hearing loss may cause dementia and believe that tackling this sensory impairment early may help to prevent the disease.

A new study compares adolescent siblings to determine the impact of early and frequent use of marijuana on cognitive function

Finally this week a new two-stage model seeks to answer a longstanding philosophical debate over whether consciousness is continuous or discrete. Findings suggest discrete consciousness is preceded by a long-lasting unconscious processing period.

 

Weekly Neuroscience Update

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Chang Lab’s research reveals what area of the human brain controls the pitch of our speech.

Researchers have revealed the area of the brain that controls our voice box, allowing us to alter the pitch of our speech. The insight could pave the way for advancing neuroprosthetics to allow people who can’t speak, to express themselves in a naturalistic way.

A new study reports the brain mechanisms responsible for triggering memory are identical, whether a person is awake or asleep.

While the effects of sleep deprivation are well known, researchers discover sleeping too much could have a detrimental effect on your brain. A new study reports sleeping more than eight hours per night can reduce cognitive ability and reasoning skills.

Researchers have discovered the thalamus plays a crucial role in the development of normal sleep and waking states.

A new study reports T cells are activated in the intestines and migrate to the brain, causing an inflammatory cascade that may lead to multiple sclerosis. Researchers say the gut microbiome may play a more significant role in the development and progression of MS than previously believed.

A new study reports an afternoon nap can help us to process unconscious information and enhance cognition.

Utilizing lesion network mapping, a recently developed technique for analyzing how the brain works, researchers have studied free will perception related to movement decisions.

A new study reports a protein made by astrocytes plays a critical role in brain plasticity by assisting with neural maturation and flexibility.

Only a small proportion of cases of dementia are thought to be inherited – the cause of the vast majority is unknown. Now, in a study published today in the journal Nature Communications, a team of scientists led by researchers at the University of Cambridge believe they may have found an explanation: spontaneous errors in our DNA that arise as cells divide and reproduces.

An international team of researchers has demonstrated, with electrophysiological evidence, the existence of grid-like activity in the human brain.

Finally, this week, a new study reports people may be able to avoid depression, even if they have a genetic predisposition to SAD, by maintaining or boosting serotonin levels throughout the year.

 

 

 

 

 

 

Weekly Neuroscience Update

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Whole brain analyses revealed that higher dispositional mindfulness during painful heat was associated with greater deactivation of a brain region called the posterior cingulate cortex, a central neural node of the default mode network. Further, in those that reported higher pain, there was greater activation of this critically important brain region. image is credited to Zeidan et al.

Ever wonder why some people seem to feel less pain than others? A  new study may have found one of the answers – mindfulness.

Researchers at the Kavli Institute for Systems Neuroscience in Norway in have discovered a network of brain cells that express our sense of time within experiences and memories.

A new study reveals elevated glial activation in the brains of those with fibromyalgia.

Brains of baby boys born prematurely are affected differently and more severely than premature infant girls’ brains. This is according to a study published in the Springer Nature-branded journal Pediatric Research.

According to researchers, the speed at which a person speaks influences the way we hear and understand upcoming words. 

A new study reports under conditions of stress, KCNB1 builds up in the brain, before becoming toxic and promoting the production of amyloid beta. In Alzheimer’s patients, the KCNB1 levels are higher than in those without the condition.

Researchers report pyramidal neurons in the basolateral amygdala help us to recognize and categorize foods.

A new study sheds additional light on how the brain consolidates memory during sleep. Researchers report rapid fluctuations in gamma band activity in the hippocampus during nREM sleep helps facilitate memory reactivation.

Finally this week, researchers report on how the brain learns to recognize an individual face, regardless of where it appears in different visual locations.

 

Weekly Neuroscience Update

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Staining one section of the brain, as shown, reveals layers of the piriform cortex–in green, brownish-red, and white–and other cells of the brain in blue. Image is credited to Salk Institute.

Researchers say the randomness of the piriform cortex plays a critical role when it comes to distinguishing between similar odors.

A new study sheds light into how we recognize facial expressions of emotion. Researchers report our interpretation of emotions expressed facially by others depends upon our pre-conceived understanding of emotion.

Scientists in Israel have developed a breath test that can detect people with early-stage Parkinson’s disease.

A new study, published in the journal PNAS, suggests that a diagnostic blood test for depression may soon be on the horizon. The new research shows that treatment-resistant depression is characterized by reduced blood levels of a specific molecule.

‘Inattentional smell blindness’, or inattentional anosmia, has been proven to exist in a new study.

Yale researchers have tested a new method for directly measuring synaptic loss in individuals with Alzheimer’s disease. The method, which uses PET imaging technology to scan for a specific protein in the brain linked to synapses, has the potential to accelerate research for new Alzheimer’s treatments.

A recent study finds that noninvasive brain stimulation, activated while asleep, improves memory performance the next day.

Finally this week, researchers have identified a neural link between depression and sleep problems. The study reports brain regions associated with short-term memory, self and negative emotions are strongly connected in those with depression, and this may lead to bad sleep quality.

Weekly Neuroscience Update

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In a collaboration between Swedish and Italian researchers, the aim was to analyse how the brain interprets information from a virtual experience of touch, created by a finger prosthesis with artificial sensation. The result was – completely unexpectedly – a new method for measuring brain health.

Stroke patients who learned to use their minds to open and close a device fitted over their paralyzed hands gained some control over their hands, according to a new study.

As children age into adolescence and on into young adulthood, they show dramatic improvements in their ability to control impulses, stay organized, and make decisions. Those ‘executive functions’ of the brain are key factors in determining outcomes, including educational success, drug use, and psychiatric illness. Now, researchers have mapped the changes in the network organization of the brain that underlie those improvements in executive function.

Despite numerous claims, researchers discover transcranial direct current stimulation likely adds no meaningful benefit to cognitive training.

Neuropsychiatric symptoms, specifically sleep behavior and irritability, are linked to metabolic dysfunction on specialized positron emission tomography (PET) imaging and may be an early noncognitive symptom of Alzheimer’s dementia, according to results published in Neurology.

Individual neurons can learn not only single responses to a particular signal, but also a series of reactions at precisely timed intervals.

Researchers from the Radboud University in the Netherlands have observed the human brain’s ability to visually “predict” future events. By scanning the brains of students during an experiment, they saw this predictive imaging in action.

Vicsoelasticity in the hippocampus is associated with better performance on both memory and fitness tests, a new study reports.

The visual cortex, the human brain’s vision-processing centre that was previously thought to mature and stabilize in the first few years of life, actually continues to develop until sometime in the late 30s or early 40s, neuroscientists have found.

New Finnish research reveals how brain’s opioids modulate responses towards other people’s pain.

Finally this week, researches report memory isn’t a single entity and memory formation can be enhanced by different brain states.

 

Weekly Neuroscience Update

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Contrary to popular belief, exposing children to stimuli early can help to boost their development, researchers report.

Dementia is more common in people who live within 50 metres of a major road than those who live further away, according to a study looking at 6.6 million people published in The Lancet.

According to a new study, clinically depressed children show a blunted response to reward compared to those who were not depressed.

Cerebral blood flow is reduced in the Broca’s area of people who stutter, researchers report. Additionally, the more severely a person stutters, the less blood flows to this area of the brain.

The same area of the brain can motivate and suppress a learned behaviour at the same time, a new study reports.

Exposure to false information about an event usually makes it more difficult for people to recall the original details, but new research suggests that there may be times when misinformation actually boosts memory.

Using objects when trying to solve problems may help to find new ways of finding a solution, researchers report.

A new study looks at how our brains process information when we pay attention and attempt to ignore stimuli.

Finally this week, researchers report Alzheimer’s can be detected before diagnosis by looking at, and applying mathematical analysis, to their painting styles.

 

 

Weekly Neuroscience Update

runner-888016_960_720.jpgAccording to researchers, endurance runners appear to have greater functional connectivity in their brains that those who don’t exercise as much.

New research reveals that children begin using olfactory information to help guide their responses to emotionally-expressive faces at about five years of age. The findings advance understanding of how children integrate different types of sensory information to direct their social behaviour.

A new study explores how neurons adapt their function to respond to stimuli quickly.

A distinctive neural signature found in the brains of people with dyslexia may explain why these individuals have difficulty learning to read, according to a new study from MIT neuroscientists.

Brain connections that play a key role in complex thinking skills show the poorest health with advancing age, new research suggests.

Researchers have identified immune cells in the membranes around the brain that could be a ‘missing link’ in the gut-brain axis. The immune cells also appear to have a positive impact on recovery following spinal cord injury.

Therapeutic hypothermia following a Traumatic Brain Injury (TBI) significantly improves survival rate, a new study reports.

An enzyme found in the fluid around the brain and spine is giving researchers a snapshot of what happens inside the minds of Alzheimer’s patients and how that relates to cognitive decline.

Finally this week,a new study looks at the way in which noise sensitivity is manifested due to changes in the way in which the brain processes auditory information.

 

 

Weekly Neuroscience Update

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A new study finds those “earworm” songs that get stuck in our heads are usually faster, fairly generic and easier to remember, but with unique intervals that set them apart from ‘average’ pop songs.

Researchers have for the first time recorded how cells of the epidermis behave during the regrowth of adult limbs after amputation.

Proper communication between the left and right sides of the brain is critical for the development of advanced language skills, according to new research.

A team of researchers at TU Dresden has examined the underlying neural processes associated with short term task learning in a current imaging study. The results of the study are published today in Nature Communications.

A new study confirms that scanning a person’s brain with an fMRI is more accurate at picking up lies than a traditional polygraph test.

Contrary to popular belief, language is not limited to speech. A  recent study published in the journal PNAS, reveals that people also apply the rules of their spoken language to sign language.

Scientists at The University of Manchester have shown for the first time that if the brain is ‘tuned-in’ to a particular frequency, pain can be alleviated.

A new study appears to build on the previous research that suggests genetic mutations which affect mitochondria function could be critical to the development and progression of Alzheimer’s disease. Meanwhile, researchers have also discovered a possible new treatment for the disease after noticing the way in which insulin signaling works in the brains and pancreas of diabetic patients; and in another study degeneration of the basal forebrain appears before cognitive and behavioural symptoms of Alzheimer’s occur.

Researchers were able to predict the orientation preference of individual neurons by adding up the responses of their dendritic spines, a new study reports.

Scientists have mapped what happens neurologically when new information influences a person to change his or her mind, a finding that offers more insight into the mechanics of learning.

The brain regulates social behaviour differently in males and females, according to a new study published in the Proceedings of the National Academy of Sciences.

A team of  researchers has uncovered new details about the biology of telomeres, “caps” of DNA that protect the tips of chromosomes and play key roles in a number of health conditions, including cancer, inflammation and aging.

A new study uses retinal prosthetics to assess the brain’s ability to process visual information years after blindness occurs.

People suffering medical conditions causing low levels of oxytocin perform worse on empathy tasks, according to new research. And a new measuring method has detected oxytocin at much higher rates in blood serum and plasma than researchers previously thought.

Researchers believe they may have pinpointed an area of the brain that plays a role in maintaining human consciousness.

Scientists have uncovered new details about how a repeating nucleotide sequence in the gene for a mutant protein may trigger Huntington’s disease and other neurological diseases.

Finally this  week, a new study reports context processing problems could help to explain some of the symptoms and neuroimaging findings associated with PTSD.