Weekly Neuroscience Update

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Axons of retinal ganglion cells (red) derived from human pluripotent stem cells bundle together and navigate their environment using growth cones (green), similar to human development of the optic nerve. NeuroscienceNews.com image is credited to Department of Biology, School of Science at IUPUI

Biologists are growing ‘mini retinas’ in the lab from stem cells to mimic the growth of the human retina. The researchers hope to use the research to restore sight when critical connections between the eye and the brain are damaged. These models also allow the researchers to better understand how cells in the retina develop and are organized. These results are published online in Scientific Reports, a Nature Research journal.

Researchers have discovered how the brain attempts to compensate for poor performance in tasks which require complicated transformation, such as writing your name backwards.

Observing the brain’s response to repeated stimuli has helped KAUST researchers develop a method for modeling connectivity patterns in neural networks. Mapping connectivity patterns will help to better understand brain function, ultimately improving diagnosis and treatment of brain diseases and mental disorders.

A new study reveals unique connections within brain networks in children on the autism spectrum. Researchers say, in ASD, the amygdala shows marked differences in connection with the occipital cortex than in typically developing children.

Researchers have identified key differences between the way males and females with schizophrenia process the emotional states of others than those without the condition. The study reports those with schizophrenia use less complex brain regions than healthy controls to process other people’s emotions.

According to a new study, certain behavioral risk factors strongly predict the likelihood of a person developing depression, and these risk factors change as we age.

Using neuroimaging technology, researchers have identified three different subtypes of depressive disorder, including one that seems to be untreatable by common SSRI antidepressants.

Finally this week, researchers report those who have had appendectomies have a reduced risk of developing Parkinson’s disease. A new study reveals the appendix acts as a reservoir for proteins associated with the neurodegenerative disease.

Weekly Neuroscience Update

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Mood is represented across multiple sites in the brain rather than localized regions, which makes decoding them a computational challenge, according to a USC expert. NeuroscienceNews.com image is credited to Sani et. al., Nature Biotechnology.

Researchers have built a decoder which is able to translate neural signals into mood variations.

How and why human-unique characteristics such as highly social behavior, languages and complex culture have evolved is a long-standing question. A research team led by Tohoku University in Japan has revealed the evolution of a gene related to such human-unique psychiatric traits.

A new study reports mast cells play a key role in determining sex differences in the developing brain.

An inhaled form of a high blood pressure medication has potential to treat certain types of anxiety as well as pain, according to a new study by the Centre for Addiction and Mental Health (CAMH).

Functional connectivity within a specific neural network helps dampen a newborn’s brain activity in response to pain, researchers report.

A new blood test can help identify your body’s precise internal time clock in relation to external time. Researchers say the test could help examine the impact of misaligned circadian clocks in a wide range of diseases.

Researchers report a neural network called the isthmic system helps us to select visual objects that catch our attention.

According to researchers, drumming for an hour a week helps improve learning at school for children on the autism spectrum. The study reports drumming not only improves dexterity, rhythm and timing for those with ASD, it also helps improve concentration and enhances communication with peers.

A new study reports those with ADHD are at an increased risk of developing Parkinson’s disease.

In one of the biggest breakthroughs in schizophrenia research in recent times, Professor Cynthia Shannon Weickert from Neuroscience Research Australia (NeuRA) and UNSW Sydney has identified immune cells in greater amounts in the brains of some people with schizophrenia.

Finally this week, esearchers are looking at what happens in the brain when we make snap decisions under stress.

 

Weekly Neuroscience Update

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Image Credit: Kolbjørn Skarpnes & Rita Elmkvist Nilsen / NTNU Communication Division & Kavli Institute for Systems Neuroscience

Researchers at the Kavli Institute for Systems Neuroscience in Norway in have discovered a network of brain cells that express our sense of time within experiences and memories.

A new study reports a strong hand grip is correlated with better visual memory and reaction times in people with psychiatric disorders, such as schizophrenia.

Dr Max Ortiz Catalan of Chalmers University of Technology, Sweden, has developed a new theory for the origin of the mysterious condition, ‘phantom limb pain’. Published in the journal Frontiers in Neurology, his hypothesis builds upon his previous work on a revolutionary treatment for the condition, that uses machine learning and augmented reality.

Researchers report ADHD and conduct disorder exhibit similar, overlapping changes in the brain.

A new study in SLEEP, published by Oxford University Press, indicates that delaying school start times results in students getting more sleep, and feeling better, even within societies where trading sleep for academic success is common.

Scientists have identified a group of blood metabolites that could help detect some children with autism spectrum disorder (ASD). 

Researchers report the adverse cognitive effects associated with DBS in Pakinson’s patients are linked to a different neural pathway than the one responsible for the motor effects generated by the treatment.

According to a new study, people who have suffered a stroke are twice as likely to develop dementia.

Researchers have developed a new deep learning neural network that can identify speech patterns indicative of depression from audio data. The algorithm is 77% effective at detecting depression.

Finally this week, a new study reports genetic factors count for about 70% of stable academic achievement throughout schooling.

 

 

Weekly Neuroscience Update

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Staining one section of the brain, as shown, reveals layers of the piriform cortex–in green, brownish-red, and white–and other cells of the brain in blue. Image is credited to Salk Institute.

Researchers say the randomness of the piriform cortex plays a critical role when it comes to distinguishing between similar odors.

A new study sheds light into how we recognize facial expressions of emotion. Researchers report our interpretation of emotions expressed facially by others depends upon our pre-conceived understanding of emotion.

Scientists in Israel have developed a breath test that can detect people with early-stage Parkinson’s disease.

A new study, published in the journal PNAS, suggests that a diagnostic blood test for depression may soon be on the horizon. The new research shows that treatment-resistant depression is characterized by reduced blood levels of a specific molecule.

‘Inattentional smell blindness’, or inattentional anosmia, has been proven to exist in a new study.

Yale researchers have tested a new method for directly measuring synaptic loss in individuals with Alzheimer’s disease. The method, which uses PET imaging technology to scan for a specific protein in the brain linked to synapses, has the potential to accelerate research for new Alzheimer’s treatments.

A recent study finds that noninvasive brain stimulation, activated while asleep, improves memory performance the next day.

Finally this week, researchers have identified a neural link between depression and sleep problems. The study reports brain regions associated with short-term memory, self and negative emotions are strongly connected in those with depression, and this may lead to bad sleep quality.

Weekly Neuroscience Update

buddhist-1807526_960_720.jpgResearchers have discovered differences in the brain’s emotional networks between those who do not meditate, novice meditators and those who have practiced meditation for a long time.

According to researchers, people find it easier to lie in a foreign language than their native tongue.

A new study could revolutionize understanding of how signal flow can be measured in the brain and could have an impact into the development of new artificial neural networks.

Scientists in the US have announced they’ve developed an Artificial Intelligence (AI) system that can tell how smart a person is just by looking at a scan of their brain.

Researchers have developed a new, non-surgical method to manipulate brain circuitry. The technique uses sound waves in combination with small bubble injections into the bloodstream that temporarily opens the blood-brain barrier.

A new study reports disrupted transportation routes in nerve cells are a significant cause of Parkinson’s disease.

According to researchers, vision and brain circuits perform regular background scans, making neurons available for focus based tasks. The process makes it possible for us to pay, and maintain attention.

Researchers report high density of neurons in the dorsolateral prefrontal cortex play a significant role in resilient dyslexia.

Finally this week, a new study reports children who exhibit excessive self-control and have tendencies toward perfectionism are twice as likely to develop OCD by their teenage years.

Weekly Neuroscience Update

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In a new study, scientists have discovered why the brain’s olfactory system is so remarkably consistent between individuals, even though the wiring of brain cells in this region differs greatly from person to person.

Scientists have proposed a new communication model to explain how brain networks can be navigated to achieve efficient information transfer.

Researchers have discovered another purpose for the gut-brain axis; relaying information to the hippocampus to store information about our environment and location.

A new study reports speech comprehension can improve as much as 10% when sound is delayed relative to vision.

Parkinson’s disease progresses differently in women than in men. A current study has now furnished the first neurophysiological evidence supporting this finding. “Numerous demographic studies have provided evidence that men contract Parkinson’s disease nearly twice as often as women.

A new study reveals the role the anterior cingulate cortex and basolateral amygdala play in observational learning.

Researchers say schizophrenia should not be considered to be just a disorder of the mind, as schizophrenia can also impact other organs. A new study reveals people with schizophrenia often have an over active immune system and other physical disorders.

Transcranial magnetic stimulation allows researchers to better understand how brain networks interact to make word choice decisions.

A new study reveals, in combination with genetics and environmental factors, placenta health during fetal development may play a role in schizophrenia. Researchers report genes associated with schizophrenia may turn on in the placenta during complicated pregnancies.

Researchers report a simple saliva test that measures cortisol levels at specific times of the day, can identify those at risk of stress and depression.

A new study reveals older adults with greater symptoms of depression have a smaller brain volume and a 55% greater chance of vascular lesions in the brain than those who do not have depression.

New research reveals the prefrontal cortex may play a role in coordinating the level of consciousness through the cholinergic system.

Finally this week, researchers report meditation and yoga are more effective at reducing stress than Chi in soldiers. Additionally, those who meditate showed stronger executive control.

Weekly Neuroscience Update

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Image credited to Ruth Litovsky (via NeuroscienceNews.com)

A new technique synchronizes cochlear signals in those with implants, stimulating the brain in a way that is similar to hearing people. This can allow those with cochlear implants to hear in stereo.

According to a new study, melatonin works by suppressing neurons that keep you awake and alert. The findings could pave the way for new treatments for insomnia.

When viewing OCD related images, those with the disorder had increased distress and higher levels of activity in emotion-related brain regions than their siblings who did not suffer from OCD, researchers report.

Magnetic resonance imaging can be used to detect the development of psychosis in the brains of high-risk patients at an early stage, according to a new study. 

Researchers have identified the mechanisms behind how noise-induced hearing loss occurs and have shown a simple injection to the middle ear may help to preserve hearing following exposure to loud blast noises.

A new article looks at theories of consciousness and novel research aimed at providing a better understanding of the roots of consciousness.

Sleep is known to be important for creative thinking, but exactly how it helps and what role each sleep stage–REM and non-REM–plays remains unclear. A team of researchers has now developed a hypothesis to explain how the interleaving of REM and non-REM sleep might facilitate creative problem-solving in different but complementary ways.

A study of Parkinson’s patients reveals neural activity alternates between the right and left sides of the brain as we walk.

A new study has linked the APOE4 gene to mental health issues some people face following TBI. Researchers report people with the APOE4 gene had significantly higher scores for depression, PTSD and anxiety following TBI than those without the genetic variant.

Finally this week, a group of researchers has uncovered a new way of telling how well people are learning English: tracking their eyes.

A new study reports people who have a family history of alcohol use disorder release more dopamine in the ventral striatum as a response to the expectation of receiving an alcoholic drink than those without a family history of alcoholism

A new study reveals children who are either overweight or obese during the first two years of life may have problems with memory and learning at the age of 5. Researchers say IQ scored may be lower for higher weight children.

A new study reveals older adults with greater symptoms of depression have a smaller brain volume and a 55% greater chance of vascular lesions in the brain than those who do not have depression.

Researchers report the critical period of language learning may be longer than previously believed. A new study reveals children remain skilled at learning new languages until age 18.

Research has shown that a developing child’s brain structure and function can be adversely affected when the child is raised in an environment lacking adequate education, nutrition and access to health care.

Scientists have uncovered dozens of genes that increase the risk of depression — a major finding that underscores the complexity of the disease and reveals why antidepressant therapies work well for some people but are utterly ineffective for others.

A new study reports Alzheimer’s disease does not appear to affect the salience network. Researchers found, when listening to music, the salience network along with other networks, show higher functional connectivity in Alzheimer’s patients.

Neuroscientists at the University of California-Berkeley are developing a technique that could give us the ability to fool our brain into thinking that we’d experienced something that never happened by manipulating electrical activity in the brain.

 

 

Weekly Neuroscience Update

 

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A new guideline for medical practitioners says they should recommend twice-weekly exercise to people with mild cognitive impairment to improve memory and thinking.

Researchers reveal Parkinson’s patients have more copies of mitochondrial DNA in the brain stem, leading to increased cell death within that area.

Musical training may enhance the ability to process speech in noisy settings, a new study shows.

A new study reveals the piriform cortex is able to archive long term memory, but requires instruction from the orbiotfrontal cortex to indicate the event is to be stored as a long-term memory.

Greater muscle strength is associated with better cognitive function in ageing men and women, according to a new Finnish study

Researchers have discovered a new biomarker that can help diagnose Huntington’s disease. They note the findings could result in the development of treatments to postpone neuron death in those who carry the Huntington’s gene mutation, but who do not currently show symptoms of the disease.

A new study reveals the superior temporal gyrus appears to be critical for voice recognition.

Researchers have identified several new genes responsible for Alzheimer’s disease (AD) including those leading to functional and structural changes in the brain and elevated levels of AD proteins in cerebrospinal fluid (CSF).

Finally this week, a new study adds to evidence that current clinical tools can fail to capture autism presentations in females.

 

 

 

Weekly Neuroscience Update

 

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A bidirectional brain-computer interface (BBCI) can both record signals from the brain and send information back to the brain through stimulation. Credit: Center for Sensorimotor Neural Engineering (CSNE).

 

Researchers are investigating advances in brain-computer interface technologies and considering the implications of linking our brains up to technology.

A new study published in the online journal Radiology suggested that disconnections in the areas of the brain, which are involved in attention and visual processing might lead to visual hallucinations in patients with Parkinson’s disease.

Researchers present a new theory about dreaming, suggesting dreams may be an accidental byproduct of our waking cognitive abilities.

Scientists have long deemed the ability to recognize faces innate for people and other primates — something our brains just know how to do immediately from birth. However, the findings of a new Harvard Medical School study published Sept. 4 in the journal Nature Neuroscience cast doubt on this longstanding view.

Genetic processes that allow cells to transform so they can mend damaged nerves have been identified by scientists.

For the first time, researchers have been able to see changes in the neural structures in specific areas of the brains of people who suffered severe abuse as children.

A new study reveals molecular details of what happens when axons are damaged or completely severed.

A researcher has discovered the molecule that stores long-term memories — it’s called calcium/calmodulin dependent protein kinase (CaMKII).

Finally, this week, how well we are able to complete simple and complex tasks depends upon the organization of subnetworks in the brain, a new study reports.

 

 

Weekly Neuroscience Update

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Salk scientist finds similar rule governing traffic flow in engineered and biological systems.

An algorithm used for the internet may help researchers learn about the human brain, researchers report.

A new blood test may be as accurate as a test requiring a painful spinal tap for differentiating Parkinson’s disease from similar disorders, according to a study published in Neurology, the medical journal of the American Academy of Neurology.

Researchers report neurons move the site of microRNA maturation away from the cytoplasm out to the dendrites.

Emotions are not innately programmed into our brains, but, in fact, are cognitive states resulting from the gathering of information, researchers conclude in the latest issue of the journal Proceedings of the National Academy of Sciences.

A new study reveals some brain systems in a dish, dubbed circuitoids, exhibit coordinated and spontaneous rhythmic activity that can drive repetitive movements.

By using magnetic resonance imaging (MRI) to study the brains of infants who have older siblings with autism, scientists were able to correctly identify 80 percent of the babies who would be subsequently diagnosed with autism at 2 years of age.

An international research team has found that when the brain “reads” or decodes a sentence in English or Portuguese, its neural activation patterns are the same.

New findings suggest that language-specialised brain areas work in constant interaction with other areas known to support other cognitive processes, such as perception and action.

Scientists have identified two distinct mechanisms in the brain that control the balance between accuracy and speed when making decisions.

When it comes to perceiving music, the human brain is much more tuned in to certain types of rhythms than others, according to a new study.

The effects a concussion has on driving a vehicle may continue to linger even after the symptoms disappear, according to University of Georgia researchers.

Scientists say neurodegenerative diseases like Alzheimer’s and Parkinson’s may be linked to defective brain cells disposing toxic proteins that make neighbouring cells sick.

New research from Lund University in Sweden has shown that intestinal bacteria can accelerate the development of Alzheimer’s disease.

New research uncovers the brain circuit involved in processing fear, which could eventually lead to new treatment options for people with mental health disorders.

Finally this week, infants as young as 20 months of age expect adults to display surprise when discovering a false belief, according to a new study.