Weekly Neuroscience Update

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A new review of neurological symptoms of COVID-19 patients reveals the disease poses a global threat to the entire nervous system, reports a study in Annals of Neurology.

Researchers have combined tools from machine learning and neuroscience to discover that the brain uses a mathematical system to organize visual objects according to their principal components.

A new system for high-density EEG helps with the imaging of the origin and path of both normal and abnormal neural activity.

Brain function depends on inhibitory cells that balance or ‘brake’ excitation. These neurons allow the brain to process information and also prevent runaway seizures. A new study however, reports that in some critical structures of the developing brain, the inhibitory neurons cause excitation rather than suppression of brain activity. The findings, published in Science Advances, could have implications for the treatment of neonatal seizures.

New research shows changes in gut mucus may contribute to Alzheimer’s, Parkinson’s, and other neurological disorders.

Researchers have identified how specific genetic mutations cause ALS. The pathway, they believe, may also be responsible for the development of frontotemporal dementia.

Cancer itself, rather than chemotherapy alone, may contribute to the development of neuropathy some patients experience.

Finally this week, results from a new study suggest that whether certain genes are expressed — turned on or off– may play a role in susceptibility to post-traumatic stress disorder (PTSD).

 

Weekly Neuroscience Update

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Researchers have created a new technique that can rapidly “print’ two-dimensional arrays of cells and proteins that mimic a variety of cellular environments in the body.
 

People who develop Parkinson’s disease before age 50 may have been born with disordered brain cells that went undetected for decades, according to new research. The research points to a drug that potentially might help correct these disease processes.

A new substance named Lu AF60097 may help reduce side effects from tricyclic antidepressants in those with severe depression.

Researchers have uncovered a key role of medial prefrontal cortex corticotropin-releasing factor interneurons for bidirectionally controlling motivated behavioral styles under stress. The findings could help in the development of new treatments for PTSD.

MIT researchers have identified a protein fragment that may inhibit COVID-19’s ability to enter human lung cells. 

Researchers have developed a new method to record brain activity at scale. The new technique could help in the development of new neuroprosthetic devices to help amputees and those with movement restricting neurological conditions.

New research suggests that eye movements may come before hand movements in actions that require a two-step decision-making process. 

A new method to accurately record brain activity at scale has been developed by researchers. The technique could lead to new medical devices to help amputees, people with paralysis or people with neurological conditions such as motor neuron disease.

Stress, loneliness, and sleep loss can weaken the immune system, leaving people more susceptible to COVID-19.

Finally this week. using robotics, researchers have uncovered mechanisms in the cerebellum and spinal cord that determine how the nervous system responds to induced changes in step length. The findings could have implications for physical rehabilitation programs for people with movement disorders.

 

 

 

 

 

 

Weekly Neuroscience Update

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A newly developed microfluidic device microfluidic device allowed researchers to keep tissue from the suprachiasmatic nucleus alive for over 25 days.

Neuroscientists have proved how different parts of the human brain work together to create and retrieve episodic memory.  Models suggested that, during formation of a memory, information is routed from cortex to hippocampus whilst retrieving a memory should see this information flow in reverse.

A collaborative study published today in the journal Cell Reports provides evidence for a new molecular cause for neurodegeneration in Alzheimer’s disease.

Researchers have identified brain circuitry differences that might be associated with suicidal behavior in individuals with mood disorders. The study, published in Psychological Medicine, provides a promising lead toward tools that can predict which individuals are at the highest risk for suicide.

A period of wakeful rest can help reduce memory intrusions associated with PTSD.

Does dementia spread gradually and evenly in all directions across the brain, or can it “jump” from one brain area to another? New research helps to settle the question by examining the progression of frontotemporal dementia.

Examining postmortem brains of autism spectrum disorder patients, researchers discover an accumulation of immune cells surrounding blood vessels in the brain.

Your personality type may influence addiction to certain drugs, a new study reveals. Those whose personalities rank higher for impulsivity are more likely to use ecstasy, while those who score higher for neurotic traits are more likely to use opioid like heroin, researchers report.

Finally this week, researchers have mapped out some of the mechanisms that may affect women’s fertility from the teenage years to menopause.

 

 

Weekly Neuroscience Update

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Image credited to Ruth Litovsky (via NeuroscienceNews.com)

A new technique synchronizes cochlear signals in those with implants, stimulating the brain in a way that is similar to hearing people. This can allow those with cochlear implants to hear in stereo.

According to a new study, melatonin works by suppressing neurons that keep you awake and alert. The findings could pave the way for new treatments for insomnia.

When viewing OCD related images, those with the disorder had increased distress and higher levels of activity in emotion-related brain regions than their siblings who did not suffer from OCD, researchers report.

Magnetic resonance imaging can be used to detect the development of psychosis in the brains of high-risk patients at an early stage, according to a new study. 

Researchers have identified the mechanisms behind how noise-induced hearing loss occurs and have shown a simple injection to the middle ear may help to preserve hearing following exposure to loud blast noises.

A new article looks at theories of consciousness and novel research aimed at providing a better understanding of the roots of consciousness.

Sleep is known to be important for creative thinking, but exactly how it helps and what role each sleep stage–REM and non-REM–plays remains unclear. A team of researchers has now developed a hypothesis to explain how the interleaving of REM and non-REM sleep might facilitate creative problem-solving in different but complementary ways.

A study of Parkinson’s patients reveals neural activity alternates between the right and left sides of the brain as we walk.

A new study has linked the APOE4 gene to mental health issues some people face following TBI. Researchers report people with the APOE4 gene had significantly higher scores for depression, PTSD and anxiety following TBI than those without the genetic variant.

Finally this week, a group of researchers has uncovered a new way of telling how well people are learning English: tracking their eyes.

A new study reports people who have a family history of alcohol use disorder release more dopamine in the ventral striatum as a response to the expectation of receiving an alcoholic drink than those without a family history of alcoholism

A new study reveals children who are either overweight or obese during the first two years of life may have problems with memory and learning at the age of 5. Researchers say IQ scored may be lower for higher weight children.

A new study reveals older adults with greater symptoms of depression have a smaller brain volume and a 55% greater chance of vascular lesions in the brain than those who do not have depression.

Researchers report the critical period of language learning may be longer than previously believed. A new study reveals children remain skilled at learning new languages until age 18.

Research has shown that a developing child’s brain structure and function can be adversely affected when the child is raised in an environment lacking adequate education, nutrition and access to health care.

Scientists have uncovered dozens of genes that increase the risk of depression — a major finding that underscores the complexity of the disease and reveals why antidepressant therapies work well for some people but are utterly ineffective for others.

A new study reports Alzheimer’s disease does not appear to affect the salience network. Researchers found, when listening to music, the salience network along with other networks, show higher functional connectivity in Alzheimer’s patients.

Neuroscientists at the University of California-Berkeley are developing a technique that could give us the ability to fool our brain into thinking that we’d experienced something that never happened by manipulating electrical activity in the brain.

 

 

Weekly Neuroscience Update

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Neuroscientists at the University of Bristol are a step closer to understanding how the connections in our brain which control our episodic memory work in sync to make some memories stronger than others. The findings, published in Nature Neuroscience, reveal a previously unsuspected division of memory function in the pathways between two areas of the brain, and suggest that certain subnetworks within the brain work separately, to enhance the distinctiveness of memories.

A new study pinpoints the brain area responsible for forming direct links between environmental stimuli and enhanced focus.

Every few seconds, our eyelids automatically shutter and our eyeballs roll back in their sockets. So why doesn’t blinking plunge us into intermittent darkness and light? New research led by the University of California, Berkeley, shows that the brain works extra hard to stabilize our vision despite our fluttering eyes.

Our personality traits are linked to differences in the thickness and volume of various parts of our brains, an international study has suggested.

Researchers have found significant differences in the brains of teens with bipolar disorder that attempt to take their lives over those with the disorder who have never attempted suicide.

Women with lower estrogen levels may be more susceptible to developing PTSD according to new research.

A new study raises the question of whether a genetic mutation associated with neurodegeneration in one environment could act in a positive way in a different setting.

Researchers report early indicators of depression and anxiety may be evident in the brain from birth.

A cutting edge, non-invasive brain stimulation technique could improve cognitive control for people with conditions such as schizophrenia and autism.

A new computerized ‘mirror game’ has been shown to give more accurate diagnosis of schizophrenia than clinical interviews.

A new study reports on how a single instance of extreme stress can lead to long term neurological changes and trauma.

Social difficulties in people with autism are exacerbated by how other people perceive them at first meeting, researchers say.

Finally this week, researchers have revealed regions of the brain implicated in delusional misidentification syndromes.

Weekly Neuroscience Update

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A new study finds those “earworm” songs that get stuck in our heads are usually faster, fairly generic and easier to remember, but with unique intervals that set them apart from ‘average’ pop songs.

Researchers have for the first time recorded how cells of the epidermis behave during the regrowth of adult limbs after amputation.

Proper communication between the left and right sides of the brain is critical for the development of advanced language skills, according to new research.

A team of researchers at TU Dresden has examined the underlying neural processes associated with short term task learning in a current imaging study. The results of the study are published today in Nature Communications.

A new study confirms that scanning a person’s brain with an fMRI is more accurate at picking up lies than a traditional polygraph test.

Contrary to popular belief, language is not limited to speech. A  recent study published in the journal PNAS, reveals that people also apply the rules of their spoken language to sign language.

Scientists at The University of Manchester have shown for the first time that if the brain is ‘tuned-in’ to a particular frequency, pain can be alleviated.

A new study appears to build on the previous research that suggests genetic mutations which affect mitochondria function could be critical to the development and progression of Alzheimer’s disease. Meanwhile, researchers have also discovered a possible new treatment for the disease after noticing the way in which insulin signaling works in the brains and pancreas of diabetic patients; and in another study degeneration of the basal forebrain appears before cognitive and behavioural symptoms of Alzheimer’s occur.

Researchers were able to predict the orientation preference of individual neurons by adding up the responses of their dendritic spines, a new study reports.

Scientists have mapped what happens neurologically when new information influences a person to change his or her mind, a finding that offers more insight into the mechanics of learning.

The brain regulates social behaviour differently in males and females, according to a new study published in the Proceedings of the National Academy of Sciences.

A team of  researchers has uncovered new details about the biology of telomeres, “caps” of DNA that protect the tips of chromosomes and play key roles in a number of health conditions, including cancer, inflammation and aging.

A new study uses retinal prosthetics to assess the brain’s ability to process visual information years after blindness occurs.

People suffering medical conditions causing low levels of oxytocin perform worse on empathy tasks, according to new research. And a new measuring method has detected oxytocin at much higher rates in blood serum and plasma than researchers previously thought.

Researchers believe they may have pinpointed an area of the brain that plays a role in maintaining human consciousness.

Scientists have uncovered new details about how a repeating nucleotide sequence in the gene for a mutant protein may trigger Huntington’s disease and other neurological diseases.

Finally this  week, a new study reports context processing problems could help to explain some of the symptoms and neuroimaging findings associated with PTSD.

 

Weekly Neuroscience Update

The study by Kep Kee Loh and Dr Ryota Kanai found that grey-matter density in the highlighted region of the brain (anterior cingulate cortex) was negatively associated with the amount of media multitasking activity. Credit Kep Kee Loh & Ryota Kanai.

The study by Kep Kee Loh and Dr Ryota Kanai found that grey-matter density in the highlighted region of the brain (anterior cingulate cortex) was negatively associated with the amount of media multitasking activity. Credit Kep Kee Loh & Ryota Kanai.

Simultaneously using mobile phones, laptops and other media devices could be changing the structure of our brains, according to new University of Sussex research.

Breathing meditation is a powerful ally for military veterans recovering from post-traumatic stress disorder (PTSD), according to research recently published in the Journal of Traumatic Stress.

Areas of the brain that respond to reward and pleasure are linked to the ability of a drug known as butorphanol to relieve itch, according to new research.

An international research team has identified gene mutations causing severe, difficult-to-treat forms of childhood epilepsy.

A chemical in the brain plays a vital role in controlling the involuntary movements and vocal tics associated with Tourette Syndrome (TS), a new study has shown.

Finally this week, the traditional understanding in neuroscience is that tactile sensations from the skin are only assembled to form a complete experience in the cerebral cortex, the most advanced part of the brain. However, this is challenged by new research findings from Lund University in Sweden that suggest both that other levels in the brain play a greater role than previously thought, and that a larger proportion of the brain’s different structures are involved in the perception of touch.

 

 

Weekly Neuroscience Update

The human brain can recognize thousands of different objects, but neuroscientists have long grappled with how the brain perceives and identifies different objects. Now researchers have discovered that the brain organizes objects based on their physical size, with a specific region of the brain reserved for recognizing large objects and another reserved for small objects.

New research suggests that it is possible to suppress emotional autobiographical memories. The study published this month by psychologists at the University of St Andrews reveals that individuals can be trained to forget particular details associated with emotional memories. The important findings may offer exciting new potential for therapeutic interventions for individuals suffering from emotional disorders, such as depression and post-traumatic stress disorder.

Neuropsychiatric conditions such as autism, schizophrenia and epilepsy involve an imbalance between two types of synapses in the brain: excitatory synapses that release the neurotransmitter glutamate, and inhibitory synapses that release the neurotransmitter GABA. Little is known about the molecular mechanisms underlying development of inhibitory synapses, but a research team from Japan and Canada has reported that a molecular signal between adjacent neurons is required for the development of inhibitory synapses.

A new study by University of Pennsylvania and Thomas Jefferson University scientists is using brain recordings to infer the way people organize associations between words in their memories.

Weekly Neuroscience Update

Visual and auditory stimuli that elicit high levels of engagement and emotional response can be linked to reliable patterns of brain activity, a team of researchers reports. Their findings could lead to new ways for producers of films, television programs and commercials to predict what kinds of scenes their audiences will respond to.

Implants that deliver pulses of light into the brain could lead to new treatments for diseases such as epilepsy and Alzheimer’s Disease.

Post traumatic stress disorder (PTSD) is a severe type of anxiety disorder that can occur after an individual experiences a traumatic event. However, at present, doctors are unable to predict who will develop these disorders. Now, a new study seeks to identify individuals who are more susceptible to long-standing disorders if exposed to a traumatic event.

Researchers have discovered how a part of the brain helps predict future events from past experiences. The work sheds light on the function of the front-most part of the frontal lobe, known as the frontopolar cortex, an area of the cortex uniquely well developed in humans in comparison with apes and other primates.

Fish cannot display symptoms of autism, schizophrenia or other human brain disorders. However, a team of MIT biologists has shown that zebrafish can be a useful tool for studying the genes that contribute to such disorders.

Johns Hopkins researchers say they have discovered one of the most important cellular mechanisms driving the growth and progression of meningioma, the most common form of brain and spinal cord tumor. A report on the discovery, published in the journal Molecular Cancer Research, could lead the way to the discovery of better drugs to attack these crippling tumors, the scientists say.

Researchers have furthered understanding of the mechanism by which the cells that insulate the nerve cells in the peripheral nervous system, Schwann cells, protect and repair damage caused by trauma and disease.

Neuroscience News Update

University of Georgia researchers have developed a map of the human brain that shows great promise as a new guide to the inner workings of the body’s most complex and critical organ.

Brains that maintain healthy nerve connections as we age help keep us sharp in later life, new research funded by the charity Age UK has found.

The brain reward systems of women with anorexia may work differently from those of women who are obese, a new study suggests.

Emotional stress caused by last year’s tsunami caused a part of some survivors’ brains to shrink, according to scientists in Japan who grasped a unique chance to study the neurological effects of trauma. On a quest to better understand post-traumatic stress disorder (PTSD), the researchers compared brain scans they had taken of 42 healthy adolescents in other studies in the two years before the killer wave, with new images taken three to four months thereafter. Among those with PTSD symptoms, they found a shrinking in the orbitofrontal cortex, a part of the brain involved in decision-making and the regulation of emotion, said a study published in the Nature journal Molecular Psychiatry.