The (Neuro) Science of Genius

What do originality and invention look like in the brain? In this interview with New York Times columnist Carl Zimmer as part of Big Think’s partnership with 92Y’s Seven Days of Genius series, neuroscientist Heather Berlin explains current research into creative “flow states”, examining what happens in the brain when rappers and jazz musicians improvise.

Weekly Neuroscience Update

researchers have developed a method to map the circuitry of the brain with a “Neuronal Positioning System” (NPS) similar to how a Global Positioning System (GPS) triangulates our location on the planet. Image credit: Dr. Shlomo Tsuriel and Dr. Alex Binshtok, Hebrew University of Jerusalem.

researchers have developed a method to map the circuitry of the brain with a “Neuronal Positioning System” (NPS) similar to how a Global Positioning System (GPS) triangulates our location on the planet. Image credit: Dr. Shlomo Tsuriel and Dr. Alex Binshtok, Hebrew University of Jerusalem.

In new research scientists have announced a “Neuronal Positioning System” (NPS) that maps the circuitry of the brain, similar to how a Global Positioning System (GPS) receiver triangulates one’s location on the planet.

EPFL scientists have developed a new method that can accurately simulate the chemical modification of the protein behind Parkinson’s disease. The technique, has opened a new way of understanding Parkinson’s, and can be expanded to other proteins and diseases as well.

Neuroscientists have found a way to activate opioid receptors with light.

New research shows that chemotherapy can lead to excessive mind wandering and an inability to concentrate. Dubbed ‘chemo-brain,’ the negative cognitive effects of the cancer treatment have long been suspected, but the study is the first to explain why patients have difficulty paying attention.

A study provides new evidence that book sharing in early childhood may promote brain development supporting reading readiness.

An international team of scientists has discovered what amounts to a molecular reset button for our internal body clock. Their findings reveal a potential target to treat a range of disorders, from sleep disturbances to other behavioral, cognitive, and metabolic abnormalities, commonly associated with jet lag, shift work and exposure to light at night, as well as with neuropsychiatric conditions such as depression and autism.

New findings provide potential explanations for the very high percentage of post-traumatic disorders in combat.

Scientists have discovered that neurons are risk takers: They use minor “DNA surgeries” to toggle their activity levels all day, every day. Since these activity levels are important in learning, memory and brain disorders, the researchers think their finding will shed light on a range of important questions.

Women may have a more difficult time than men in recovering from concussion, according to a new study published online in the journal Radiology.

Finally this week, researchers report a previously unappreciated phenomenon in which the location of injury to a neuron’s communication wire in the spinal cord — the axon — determines whether the neuron simply stabilizes or attempts to regenerate. The study, published by Neuron, demonstrates how advances in live-imaging techniques are revealing new insights into the body’s ability to respond to spinal cord injuries.

 

 

What actually makes us happy?

fun

Recently, Gallup surveyed people across 158 countries about their happiness and reported that Switzerland came out on top while four of the five least happy countries in the world were Rwanda, Benin, Burundi and Togo.  Gallup also argued that most of the differences in happiness could be explained by just six factors:

  1. Real GDP per capita
  2. Healthy life expectancy
  3. Having someone to count on
  4. Perceived freedom to make life choices
  5. Freedom from corruption,
  6. Generosity

However, I believe that this survey missed something fundamental about the nature of individual human happiness.

Happiness is within you.

As I explained in previous posts, it is an astonishing fact that the recipe for individual human happiness can be summarized into just one sentence and here it is.

Your happiness is determined by an ability to engage and respond appropriately to the people, things and events that surround you.

Notice from this sentence, that your own individual happiness depends on YOU alone and not the people, things and events that surround you.  Ultimately whether you are..

  1. Male or female
  2. Old or young
  3. Able bodied or not
  4. Alone or in company
  5. A local or a stranger
  6. Confident or timid

..each one of us has the power to regulate our own happiness – a fact that the happiest people in the world already know.

Holders of Swiss passports and those living in sub-Saharan Africa take note.

Weekly Neuroscience Update

 

Brain-scan-images-by-Hospital-Sant-Pau-702x336

A new study published in the American journal with the highest impact factor in worldwide,Molecular Psychiatry, reveals that consumers of cannabis are more prone to experiencing false memories.

Excessive movement common among children with attention-deficit/hyperactivity disorder is actually vital to how they remember information and work out complex cognitive tasks, a new study shows. The findings show the longtime prevailing methods for helping children with ADHD may be misguided.

Brain scans of students from contrasting backgrounds have made visible the legacy of a challenging childhood. Important brain regions are more developed among children raised in a comfortable home environment.

New research published in the journal Nature Communications represents a potentially fundamental shift in our understanding of how nerve cells in the brain generate the energy needed to function. The study shows neurons are more independent than previously believed and this research has implications for a range of neurological disorders.

Every time you make a memory, somewhere in your brain a tiny filament reaches out from one neuron and forms an electrochemical connection to a neighbouring neuron. A team of biologists at Vanderbilt University is studying how these connections are formed at the molecular and cellular level.

Finally this week, among the advice new parents receive is to read to their babies early and often. The hope is that sharing books together will help children’s language development and eventually, turn them into successful readers. Now there is evidence that reading to young children is in fact associated with differences in brain activity supporting early reading skills.

Weekly Neuroscience Update

The strength of brain areas mapped on to the cortical surface. Warm colors indicate high strength in the driver network and cool colors indicate low strength. Image credit: UCSB.

The strength of brain areas mapped on to the cortical surface. Warm colors indicate high strength in the driver network and cool colors indicate low strength. Image credit: UCSB.

A team of researchers provides new insight into what occurs in the brain during the learning process.

Neuroscientists have discovered how the powerful brain hormone oxytocin acts on individual brain cells to prompt specific social behaviors – findings that could lead to a better understanding of how oxytocin and other hormones could be used to treat behavioral problems resulting from disease or trauma to the brain.

Infants have innate knowledge about the world and when their expectations are defied, they learn best, researchers at Johns Hopkins University found.

Research on large-scale brain networks by the University of Michigan Medical School reveals that “hubs” in the brain – highly connected regions that like hubs of the airport system – tend to consistently attract information flow.

Over 70% of schizophrenia patients who are “treatment resistant” have apparently developed dopamine supersensitivity psychosis from long-term use of antipsychotic medications, according to a study in Psychiatry Research.

Meaningful activities experienced with others may reverse the normal brain shrinkage associated with the aging process.

Researchers from Royal Holloway, University of London have found that successful long-term learning happens after classroom teaching, after the learners have slept on the new material.

An international team of researchers have revealed in a collaborative study published in Neuron, that neurons in the eye change on the molecular level when they are exposed to prolonged light. The researchers could identify that a feedback signalling mechanism is responsible for these changes. The innate neuronal property might be utilized to protect neurons from degeneration or cell death in the future.

Finally this week, while recent reports question whether fish oil supplements support heart health, UC Irvine scientists have found that the fatty acids they contain are vitally important to the developing brain.

 

Building Ethical Brains

ethical brain

 

I was one of seven academics selected to write opinion pieces for the Royal Irish Academy’s Ethics & Society Opinion Series, as part of President of Ireland Michael D. Higgins’s Ethics Initiative.

The essay entitled Building ethical brains is published today on the Royal Irish Academy website at ria.ie and is a follow-up to my previous posts on the influence of science on society.

Some of the ideas in this essay are developed further in the weekly Irish Times ‘Unthinkable’ ideas/philosophy column under the headline: Is rewiring the brain the answer to ethics? – also published today in the Irish Times.  In this article I argue that ignoring developments in neuroscience means neglecting a chance to become more ethical.

Weekly Neuroscience Update

age-brain-related-changes-autism

Researchers at the University of Miami find that large-scale connectivity in autism changes with age.

Although scientists know that depression affects the brain, they don’t know why some people respond to treatment while others do not. Now a team of researchers has shown for the first time in a large cohort of patients that electroconvulsive therapy (ECT), sometimes referred to as shock treatment, change certain areas of the brain that play a role in how people feel, learn and respond to positive and negative environmental factors.

Research by biologists at the University of York has identified new mechanisms potentially driving progression of an aggressive form of dementia.

A new study shows that the act of remembering leads to the subtle forgetting of other memories.

When we look at a known word, our brain sees it like a picture, not a group of letters needing to be processed. That’s the finding from a Georgetown University Medical Center (GUMC) study published in the Journal of Neuroscience, which shows the brain learns words quickly by tuning neurons to respond to a complete word, not parts of it.

Scientists at the University of Bonn have discovered a new cause of temporal lobe epilepsy.

Brown fat tissue, the body’s “good fat,” communicates with the brain through sensory nerves, possibly sharing information that is important for fighting human obesity, such as how much fat we have and how much fat we’ve lost, according to research published in the Journal of Neuroscience.

Finally this week, people who have suffered serious head injuries show changes in brain structure resembling those seen in older people, according to a new study.

 

Can We Reverse Engineer The Brain?

“The brain can do things computers can’t. We still don’t know the software of the brain, so we have to study its wiring and circuitry and build computer systems that work the same way,” says David Cox, Professor of Molecular and Cellular Biology and Computer Science, Harvard University.

Author: David Cox is an Assistant Professor of Molecular and Cellular Biology and of Computer Science, and is a member of the Center for Brain Science at Harvard University.