Weekly Neuroscience Update

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Sleep-deprived brain cells react more slowly and fire more weakly, and their signals are more drawn out. NeuroscienceNews.com image is credited to UCLA.

A Japanese research group has revealed that elderly people with mild cognitive impairment (MCI) have a particularly weakened ability to memorize human faces in the short term when compared to healthy elderly people. MCI patients also had a different gaze behavior when trying to memorize a face. This research may lead to the early detection of dementia.

Researchers provide new insight into human consciousness, reporting we don’t consciously choose our feelings or thoughts; we simply become aware of them.

If a mother’s immune system is activated by infection during pregnancy, it could result in critical cognitive deficits linked to schizophrenia in her offspring, a new study has revealed.

People on the autism spectrum appear to have different reactions to subliminal social odors, researchers report.

Information from brain MRIs can help identify people with attention deficit hyperactivity disorder (ADHD) and distinguish among subtypes of the condition, according to a study appearing online in the journal Radiology.

Migraine triggers can increase oxidative stress, a new study reports. Targeting oxidative stress may help to prevent migraines.

A new study reveals how the mechanism for storing olfactory memories differs slightly from erasing unnecessary memories. Understanding how the brain gets rid of unimportant memories could help unlock new avenues of research to better understand memory loss in aging, researchers say.

Finally this week, researchers report a developmental abnormality more prevalent in premature and male babies, may contribute to SIDS risk, in conjunction to the sleep position.

 

 

Weekly Neuroscience Update

dog-2751115_960_720.jpgThe tendency of dogs to seek contact with their owners is associated with genetic variations in sensitivity for the hormone oxytocin, according to a new study from Linköping University, Sweden.

A new study reveals schizophrenia is up to 79% hereditary.

Metacognition of a tactile working memory task has been demonstrated by researchers for the first time. Understanding this brain function might help in the development of new treatments for neuropsychiatric illnesses in the future.

Researchers have shed light on how motor signals help sharpen our ability to decipher complex sound flows.

Increased communication between distant brain regions helps older adults compensate for the negative aspects of ageing, reports a new study published this week in Human Brain Mapping.

Scientists report brain network organization changes can influence executive function in young adults.

A news study has found that brain functions in young men and women are changed by long-term alcohol use, but that these changes are significantly different in men and women.

Mindfulness and meditation can affect brain plasticity, resulting in the ability for adults to acquire new social skills, researchers report.

A new study has found that chronic tinnitus (ringing or buzzing in the ears) is associated with changes in certain networks in the brain, and furthermore, those changes cause the brain to stay more at attention and less at rest.

Finnish researchers have revealed how eating stimulates brain’s endogenous opioid system to signal pleasure and satiety.

Finally this week, sleep deprivation — typically administered in controlled, inpatient settings — rapidly reduces symptoms of depression in roughly half of depression patients, according to the first meta-analysis on the subject in nearly 30 years.

 

Weekly Neuroscience Update

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Thousands of branches and branchlets emanate from an astrocyte’s cell body, which is the dense portion in the middle of the image.

A new study published in Neuron challenges the idea that astrocytes across the brain are largely identical.

Researchers have identified a new protein, CIB2, that is key to helping the auditory system to turn soundwaves into meaningful brain signals. Mutations of this gene leave people unable to convert the soundwaves into signals that the brain can interpret, and are deaf.

The more regularly people report doing word puzzles such as crosswords, the better their brain function in later life, a large-scale online trial has found.

How short-term memories become long-term ones has frequently been explored by researchers. While a definitive answer remains elusive, scientists conclude that this transformation is best explained by a “temporal hierarchy” of “time windows” that collectively alter the state of the brain.

Greater muscle strength is associated with better cognitive function in ageing men and women, according to a new Finnish study.

Researchers at King’s College London have identified a molecular mechanism that allows neural connections to adapt as a result of experience. This adaptation fuels our ability for memory and learning.

Researchers have developed a concept called Empowerment to help robots and humans to work and live side-by-side safely and effectively.

A study of post-traumatic stress disorder (PTSD) has identified a new potential mechanism contributing to the biology of the disorder that may be targeted by future treatments.

A new study reveals those who die at 100 tend to suffer from fewer diseases than those who die at younger ages.

A new paper identifies 100 of the most cited neuroscience research papers. Of these papers, 78 focus on five topics. According to the authors of the paper, the most cited neuroscience research topics include the prefrontal cortex, neural connectivity, methodology, brain mapping and neurological disorders. The findings could have significant impact for future neuroscience studies.

Changes in the brain’s structure that could be the result of depression have been identified in a major scanning study.

The same mechanisms that quickly separate mixtures of oil and water are at play when controlling the organization in an unusual part of our DNA called heterochromatin, according to a new study.

New research has shown just how adaptive the brain can be, knowledge that could one day be applied to recovery from conditions such as stroke.

Changes in the orbitofrontal cortex and basolateral amygdala may help explain a person’s preference for uncertain outcomes, as well as a preference for order and certainty, a new study reports.

Finally this week, a small patch of neurons in the brain can encode the movements of many body parts, according to new research.

Weekly Neuroscience Update

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Our brain is especially good at perceiving lines and contours even if they do not actually exist, such as the blue triangle in the foreground of this optical illusion. The pattern of neuronal connections in the brain supports this ability.

Researchers have identified how our brains are so good at perceiving contours and edges. The study, published in Nature, reports neurons are most likely to connect if they react to edges that lie on a common axis and the structure of the world around us is mirrored in the pattern of synapses.

A new study reports bilingual people think about time differently depending on the language context they are estimating event duration.

The first large study to rigorously examine brain-training games using cognitive tests and brain imaging adds to evidence that they are not particularly good at training brains and appear to have no more effect on healthy brains than video games.

Scientists report that listening to something while looking in a different direction may slow reaction times and increase the effort for auditory attention.

The part of the brain that helps control emotion may be larger in people who develop post-traumatic stress disorder (PTSD) after brain injury compared to those with a brain injury without PTSD, according to a new study.

Researchers are investigating why certain language abilities are lost as a result of a traumatic brain injury, and how others can be regained.

A recently published study investigates time perception and temporal information processing in people with schizophrenia. It reveals the internal clock in schizophrenics does not necessarily run slower or faster than in healthy individuals, but rather it does not run at a consistent speed.

Finally, this week, using music to learn a physical task develops an important part of the brain, according to a new study.

 

Weekly Neuroscience Update

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This latest research builds on the pioneering use of machine learning algorithms with brain imaging technology to “mind read.” The findings indicate that the mind’s building blocks for constructing complex thoughts are formed by the brain’s various sub-systems and are not word-based.  Image is credited to Carnegie Mellon University.

Researchers report they can use brain activation patterns to identify complex thoughts. Their findings suggest the building blocks for complex human thoughts are not word based, but formed by the brain’s sub systems. The study provides evidence that the neural dimensions of concept representation are universal across people and languages.

A new study considers how echolocation can benefit visually impaired people to navigate safely through the environment.

Neuroscientists have used a classic branch of maths in a totally new way to peer into the structure of our brains. What they’ve discovered is that the brain is full of multi-dimensional geometrical structures operating in as many as 11 dimensions.

People tend to change the pitch of their voice depending on who they are talking to, and how dominant they feel, a new study has found.

Researchers have identified a network of neurons that plays a vital role in learning vocalizations by aiding communication between motor and auditory regions of the brain.

A new study reinforces the idea that serotonin, a molecule associated with mood, directly contributes to the actions of cocaine.

A new report published by the National Academies of Sciences, Engineering, and Medicine shows evidence supporting three interventions for cognitive decline and dementia—cognitive training, blood pressure management for people with hypertension, and increased physical activity, which might slow down cognitive decline and the onset of dementia.

Therapies to change the bacteria in the gut, through diet, pro-and prebiotic supplements, faecal matter transplants or antibiotics, could treat autism.

Finally this week, researchers say a protein usually associated with the immune system could play a role in the development of neurological conditions such as epilepsy and schizophrenia.

 

Weekly Neuroscience Update

girl-1990347_960_720.jpgA new report reveals how the development of music is so closely tied to our own evolution.

Even a single bout of physical activity can have significant positive effects on people’s mood and cognitive functions, according to a new study in Brain Plasticity.

A new study reports on the complex brain connections employed during word retrieval.

New research provides an unprecedented level of resolution and insight into disturbances in cortical GABAergic microcircuits, which are thought to underlie cognitive impairments in schizophrenia.

A sign language study helps researchers better understand how the brain processes language.

Researchers say the goal of memory is not to transmit the most accurate information over time, but to optimize intelligent decision making by holding on to valuable information.

A new study reports microglia may play a role in a diverse array of neurodegenerative and psychiatric illnesses.

A new brain imaging study shows for the first time that brain inflammation is significantly elevated – more than 30 per cent higher – in people with obsessive-compulsive disorder (OCD) than in people without the condition.

A research team has studied two structurally-similar proteins in the adult brain and have found that they play distinct roles in the development of dementia. 

Neurons found to be abnormal in psychosis play an important role in our ability to distinguish between what is real and what is perceived, researchers say.

A new study sheds light on the neural mechanism behind why some people with autism are unable to make eye contact with others.

While researchers report the risk of developing psychosis from cannabis use is relatively small, those who use the drug and already suffer from schizophrenia may notice their condition worsen.

Finally this week, researchers have discovered a mechanism of glucose sensing by muscles that contribute to the regulation of blood sugar levels in the body.

Weekly Neuroscience Update

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image credited to Per Uvdal

New technology allows researchers to produce images that predate the formation of amyloid beta in the brain. The findings have prompted researchers to suggest stabilizing the protein, rather than attempting to limit it, in order to reduce Alzheimer’s symptoms.

new study shines light on the process by which head injuries lead to brain disease later in life. 

A new type of long-term potentiation that is controlled by kainate receptors has been reported by scientists. The finding could have major benefits to understanding how the brain works and what goes wrong in neurodegenerative disorders such as epilepsy and dementia.

According to researchers, axons coordinate each other’s destruction, contributing to neurodegeneration.

Dendrites are not just passive conduits, a new study reports. The finding could change scientists’ understanding of how the brain works, and lead to new approaches for treating neurological disorders.

Structural differences have been found in the cerebral cortex of patients with depression, and these differences normalize with appropriate medication,  a new study reports.

Researchers at Karolinska Institutet collaborating in the large-scale Karolinska Schizophrenia Project are taking an integrative approach to unravel the disease mechanisms of schizophrenia. In the very first results now presented in the prestigious scientific journal Molecular Psychiatry, the researchers show that patients with schizophrenia have lower levels of the vital neurotransmitter GABA as well as changes in the brain’s immune cells.

Finally this week, researchers have identified a genetic variant that can accelerate normal brain aging in older people by up to 12 years.

 

 

 

 

 

Weekly Neuroscience Update

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Cheese contains a chemical found in addictive drugs, scientists have found.

Chronic marijuana use disrupts the brain’s natural reward processes, according to researchers at the Center for BrainHealth at The University of Texas at Dallas.

Understanding the relation of dopamine to network activity could improve schizophrenia treatment.

Using MRI brain scans, researchers have determined there is an association between the extent of disruption to the blood-brain barrier and the severity of bleeding following a stroke.

Researchers have proposed a computational model that could help explain multisensory integration in humans.

Scientists have developed a blood test that could identify which people with depression will respond to treatment so that patients can avoid spending months taking antidepressants that do not help them.

Researchers have discovered a unique pattern of scarring in the brains of those who were exposed to blast brain injuries that differs from those exposed to other types of head injury.

Intensive physical exercise four hours after learning is the key to remembering information learnt, say Dutch researchers.

Scientists have discovered a new cause of Parkinson’s disease – mutations in a gene called TMEM230. This appears to be only the third gene definitively linked to confirmed cases of Parkinson’s disease.

Finally this week, a protein called Scribble appears to orchestrate the intracellular signaling process for forgetting, a new study reports.

 

Weekly Neuroscience Update

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Researchers show how brain connections, or synapses, are lost early in Alzheimer’s disease and demonstrate that the process starts, and could potentially be halted, before telltale plaques accumulate in the brain.

Older adults who exercise regularly could buy an extra decade of good brain functioning, a new study suggests.

Researchers have identified an area of the brain that helps us to perceive boundaries.

Using a sophisticated MRI technique, researchers have found abnormalities in the brain’s white matter tracts in patients with insomnia. Results of the study were published online in the journal Radiology.

A pioneering new study has revealed how an individual’s movement can give a unique insight into their inherent personality traits.

The fluctuations of your heartbeat may affect your wisdom, according to new research.

Researchers have found that the emotional impact experienced by music listeners depends on the concert hall’s acoustics.

Lysergic acid diethylamide (LSD) use causes changes in the way that people think about time that may help develop drug therapies for people suffering from depression, according to a study published in the Journal of Psychopharmacology.

Repeated minor trauma to the head and other body parts can lead to early dementia, according to a new study.

The risk of schizophrenia in children associated with younger and older maternal age appears to be partly explained by the genetic association between schizophrenia and age at first birth, according to an article published online by JAMA Psychiatry.

A new imaging study shows that intense exercise boosts two critical neurotransmitters — glutamate and gamma-aminobutyric acid (GABA) — resulting in better mental fitness.

Religion and science activate different networks in the brain and each suppresses the other, new research finds.

Sensory neurons in human muscles provide important information used for the perception and control of movement. Learning to move in a novel context also relies on the brain’s independent control of these sensors, not just of muscles, according to a new study published in the journal Current Biology.

Finally this week, women with Alzheimer’s have poorer cognitive abilities than men at the same stage of the disease, according to a new paper published in World Journal of Psychiatry.

 

Weekly Neuroscience Update

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Dr. William Jagust explains how tau and beta amyloid, two proteins associated with Alzheimer’s disease, develop in the aging brain, which his research team has visualized using positron emission tomography, or PET, scans. Photo by Stephen McNally/University of California Berkeley

Researchers have visualized the development of Alzheimer’s disease in the brain in living people using positron emission tomography, or PET scans, which they say will aid with its diagnosis and treatment. 

Researchers have  also identified a drug that targets the first step in the toxic chain reaction leading to the death of brain cells, suggesting that treatments could be developed to protect against Alzheimer’s disease, in a similar way to how statins are able to reduce the risk of developing heart disease.

new study shows that a variety of physical activities from walking to gardening and dancing can improve brain volume and cut the risk of Alzheimer’s disease by 50%.

In another study jointly led by King’s College London and the University of Southampton has found a link between gum disease and greater rates of cognitive decline in people with early stages of Alzheimer’s Disease.

Women may have a better memory for words than men despite evidence of similar levels of shrinkage in areas of the brain that show the earliest signs of Alzheimer’s disease, according to a study published in Neurology.

Refugees face a substantially higher risk of psychotic disorders, including schizophrenia, compared to non-refugee migrants from the same regions of origin, finds a study published in The BMJ

Research on decision-making bias found that interactive training exercises using video games improved participants’ general decision-making abilities when used alongside other traditional training methods.

Reducing a person’s calorie intake can protect against the development of neurodegenerative diseases such as Parkinson’s Disease.  Meanwhile, researchers may be closer to unraveling the underlying causes of Parkinson’s disease, after identifying the point at which alpha-synuclein – a protein believed to play a key role in the condition – becomes toxic to the brain.

Scientists have developed a 3D micro-scaffold technology that promotes reprogramming of stem cells into neurons, and supports growth of neuronal connections capable of transmitting electrical signals.

Finally this week, researchers in Japan have found that repetitive movements in slow-learning stages can alter an area of the brain responsible for movement, and help individuals retain these motor skills.