Tag: schizophrenia

Weekly Neuroscience News

An early childhood surrounded by books and educational toys will leave positive fingerprints on a person’s brain well into their late teens, a two-decade-long research study has shown.

Dopamine is a neurotransmitter that is associated with emotions, movement, and the brain’s pleasure and reward system. In the current issue of Advances in Neuroimmune Biology, investigators provide a broad overview of the direct and indirect role of dopamine in modulating the immune system and discuss how recent research has opened up new possibilities for treating diseases such as Parkinson’s and Alzheimer’s disease, schizophrenia, multiple sclerosis or even the autoimmune disorders.

Studies released this week explore the neurological component of dietary disorders, uncovering evidence that the brain’s biological mechanisms may contribute to significant public health challenges — obesity, diabetes, binge eating, and the allure of the high-calorie meal.

By peering into students’ brains, a recent study, published in the journal NeuroImage, found that learning languages can help bulk up the brain.

Research is helping reveal how human and primate brains process and interpret facial expressions, and the role of facial mimicry in everything from deciphering an unclear smile to establishing relationships of power and status.

Neuroscientists from New York University and the University of California, Irvine have isolated the “when” and “where” of molecular activity that occurs in the formation of short-, intermediate-, and long-term memories. Their findings, which appear in the journal the Proceedings of the National Academy of Sciences, offer new insights into the molecular architecture of memory formation and, with it, a better roadmap for developing therapeutic interventions for related afflictions.

An inexpensive, five-minute eye scan can accurately assess the amount of brain damage in people with the debilitating autoimmune disorder multiple sclerosis (MS), and offer clues about how quickly the disease is progressing, according to results of two Johns Hopkins studies.

Weekly Neuroscience Update

Neuroscientists have announced a longitudinal research collaboration to investigate the emotional, social and cognitive effects of musical training on childhood brain development. The five-year research project, Effects of Early Childhood Musical Training on Brain and Cognitive Development, will offer USC researchers an important opportunity to provide new insights and add rigorous data to an emerging discussion about the role of early music engagement in learning and brain function.

UCLA researchers have for the first time measured the activity of a brain region known to be involved in learning, memory and Alzheimer’s disease during sleep. They discovered that this part of the brain behaves as if it’s remembering something, even under anesthesia, a finding that counters conventional theories about memory consolidation during sleep.

New research reveals that stroke may be affecting people at a younger age. The study is published in the October 10, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

Scientists studying a rare genetic disorder have identified a molecular pathway that may play a role in schizophrenia, according to new research in the October 10 issue of The Journal of Neuroscience. The findings may one day guide researchers to new treatment options for people with schizophrenia — a devastating disease that affects approximately 1 percent of the world’s population.

Researchers from the University of Exeter Medical School have for the first time identified the mechanism that protects us from developing uncontrollable fear.

Small amounts of the drug ketamine can immediately relieve the symptoms of chronic depression, as well as those of treatment-resistant patients within a few hours, say Yale scientists.

Scientists find that competition between two brain regions influences the ability to make healthy choices.

A compassion-based meditation program can significantly improve a person’s ability to read the facial expressions of others, finds a study published by Social Cognitive and Affective Neuroscience. This boost in empathic accuracy was detected through both behavioral testing of the study participants and through functional magnetic resonance imaging (fMRI) scans of their brain activity.

A study in PLOS ONE shows that whether or not you like the person you’re watching can actually have an effect on brain activity related to motor actions and lead to “differential processing” – for example, thinking the person you dislike is moving more slowly than they actually are.

Weekly Neuroscience Update

A growing body of evidence suggests that learning to play an instrument and continuing to practice and play it may offer mental benefits throughout life. Hearing has also been shown to be positively affected by making music. The latest study, published in the July issue of Frontiers in Human Neuroscience, shows that musical instrument training may reduce the effects of mental decline associated with aging. The research found that older adults who learned music in childhood and continued to play an instrument for at least 10 years outperformed others in tests of memory and cognitive ability.

Neuroscientists are finding that, as we get older, our aging brains are proving surprisingly malleable, and in ways not previously anticipated. But there are limitations. There is growing evidence that, beyond what was previously believed, the adult human brain is remarkably malleable and capable of new feats — even in the last decades of life. And UCLA researchers found that older adults who regularly used a brain fitness program played on a computer demonstrated significantly improved memory and language skills.

From older to younger brains now…

Determining when a teenage brain becomes an adult brain is not an exact science but it’s getting closer, according to an expert in adolescent developmental psychology, speaking at the American Psychological Association’s 120th Annual Convention.

Researchers at Aalto University in Finland have developed the world’s first device designed for mapping the human brain that combines whole-head magnetoencephalography (MEG) and magnetic resonance imaging (MRI) technology. MEG measures the electrical function and MRI visualizes the structure of the brain. The merging of these two technologies will produce unprecedented accuracy in locating brain electrical activity non-invasively

According to a study conducted by the National Institutes of Health, children with attention-deficit/hyperactivity disorder (ADHD) experience a developmental delay in frontal regions of the brain.

The brain differences found in people with schizophrenia are mainly the result of the disease itself or its treatment, as opposed to being caused by genetic factors, according to a Dutch study

Bilingual children outperform children who speak only one language in problem-solving skills and creative thinking, according to research led at the University of Strathclyde.

When we focus intently on one task, we often fail to see other things in plain sight – a phenomenon known as ‘inattention blindness’. Scientists already know that performing a task involving high information load – a ‘high load’ task – reduces our visual cortex response to incoming stimuli. Now researchers from UCL have examined the brain mechanisms behind this, further explaining why our brain becomes ‘blind’ under high load.

A tale of mental illness from the inside

Elyn Saks asks bold questions about how society treats people with mental illness.

A legal scholar, in 2007 Elyn Saks came forward with her own story of schizophrenia, controlled by drugs and therapy but ever-present. In this powerful talk, she asks us to see people with mental illness clearly, honestly and compassionately.

 

Weekly Neuroscience Update

The human brain can recognize thousands of different objects, but neuroscientists have long grappled with how the brain perceives and identifies different objects. Now researchers have discovered that the brain organizes objects based on their physical size, with a specific region of the brain reserved for recognizing large objects and another reserved for small objects.

New research suggests that it is possible to suppress emotional autobiographical memories. The study published this month by psychologists at the University of St Andrews reveals that individuals can be trained to forget particular details associated with emotional memories. The important findings may offer exciting new potential for therapeutic interventions for individuals suffering from emotional disorders, such as depression and post-traumatic stress disorder.

Neuropsychiatric conditions such as autism, schizophrenia and epilepsy involve an imbalance between two types of synapses in the brain: excitatory synapses that release the neurotransmitter glutamate, and inhibitory synapses that release the neurotransmitter GABA. Little is known about the molecular mechanisms underlying development of inhibitory synapses, but a research team from Japan and Canada has reported that a molecular signal between adjacent neurons is required for the development of inhibitory synapses.

A new study by University of Pennsylvania and Thomas Jefferson University scientists is using brain recordings to infer the way people organize associations between words in their memories.

Weekly Neuroscience Update

Visual and auditory stimuli that elicit high levels of engagement and emotional response can be linked to reliable patterns of brain activity, a team of researchers reports. Their findings could lead to new ways for producers of films, television programs and commercials to predict what kinds of scenes their audiences will respond to.

Implants that deliver pulses of light into the brain could lead to new treatments for diseases such as epilepsy and Alzheimer’s Disease.

Post traumatic stress disorder (PTSD) is a severe type of anxiety disorder that can occur after an individual experiences a traumatic event. However, at present, doctors are unable to predict who will develop these disorders. Now, a new study seeks to identify individuals who are more susceptible to long-standing disorders if exposed to a traumatic event.

Researchers have discovered how a part of the brain helps predict future events from past experiences. The work sheds light on the function of the front-most part of the frontal lobe, known as the frontopolar cortex, an area of the cortex uniquely well developed in humans in comparison with apes and other primates.

Fish cannot display symptoms of autism, schizophrenia or other human brain disorders. However, a team of MIT biologists has shown that zebrafish can be a useful tool for studying the genes that contribute to such disorders.

Johns Hopkins researchers say they have discovered one of the most important cellular mechanisms driving the growth and progression of meningioma, the most common form of brain and spinal cord tumor. A report on the discovery, published in the journal Molecular Cancer Research, could lead the way to the discovery of better drugs to attack these crippling tumors, the scientists say.

Researchers have furthered understanding of the mechanism by which the cells that insulate the nerve cells in the peripheral nervous system, Schwann cells, protect and repair damage caused by trauma and disease.

Your Weekly Neuroscience Update

You’re running late for work and you can’t find your keys. What’s really annoying is that in your frantic search, you pick up and move them without realising. This may be because the brain systems involved in the task are working at different speeds, with the system responsible for perception unable to keep pace. So says Grayden Solman and his colleagues at the University of Waterloo in Ontario, Canada.

Scientists have now discovered how different brain regions cooperate during short-term memory  and in other research -findings that a prion-like protein plays a key role in storing long-term memories

Memories in our brains are maintained by connections between neurons called “synapses”. But how do these synapses stay strong and keep memories alive for decades? Neuroscientists at the Stowers Institute for Medical Research have discovered a major clue from a study in fruit flies: Hardy, self-copying clusters or oligomers of a synapse protein are an essential ingredient for the formation of long-term memory.

Researchers reveal a novel mechanism through which the brain may become more reluctant to function as we grow older.

New research from Uppsala University shows that reduced insulin sensitivity is linked to smaller brain size and deteriorated language skills in seniors. The findings are now published in the scientific journal Diabetes Care.

Age-related delays in neural timing are not inevitable and can be avoided or offset with musical training, according to a new study from Northwestern University. The study is the first to provide biological evidence that lifelong musical experience has an impact on the aging process.

Could brain size determine whether you are good at maintaining friendships? Researchers are suggesting that there is a link between the number of friends you have and the size of the region of the brain – known as the orbital prefrontal cortex – that is found just above the eyes. A new study, published today in the journal Proceedings of the Royal Society B, shows that this brain region is bigger in people who have a larger number of friendships.

Scientists have long believed that human speech is processed towards the back of the brain’s cerebral cortex, behind auditory cortex where all sounds are received – a place famously known as Wernicke’s area after the German neurologist who proposed this site in the late 1800s based on his study of brain injuries and strokes. But, now, research that analyzed more than 100 imaging studies concludes that Wernicke’s area is in the wrong location. The site newly identified is about 3 centimeters closer to the front of the brain and on the other side of auditory cortex – miles away in terms of brain architecture and function.

New research from Cold Spring Harbor Laboratory (CSHL) might help explain how a gene mutation found in some autistic individuals leads to difficulties in processing auditory cues and paying spatial attention to sound.

Neuroscientists may one day be able to hear the imagined speech of a patient unable to speak due to stroke or paralysis, according to University of California, Berkeley, researchers.

Cocaine-dependent men and women might benefit from different treatment options, according to a study conducted by Yale School of Medicine researchers.

New research finds problems that require a flash of illumination to solve are best approached during the time of day when you’re not at your peak.

Researchers for the first time are documenting the basic wiring of the brain, the complex relationships among billions of neurons that are responsible for reason, memory and emotion. The work eventually could lead to better understanding of schizophrenia, autism, multiple sclerosis and other disorders.

Weekly Round Up

A part of the human brain that’s involved in emotion gets particularly excited at the sight of animals, a new study has shown. The brain structure in question is the amygdala: that almond-shaped, sub-cortical bundle of nuclei that used to be considered the brain’s fear centre, but which is now known to be involved in many aspects of emotional learning.

Studies have shown that ­meditating regularly can help relieve chronic pain, but the neural mechanisms ­underlying the relief were unclear. Now, ­researchers from MIT, Harvard, and Massachusetts General ­Hospital have found a possible explanation.

Men and women differ in the way they anticipate an unpleasant emotional experience, which influences the effectiveness with which that experience is committed to memory according to new research.

New research has contradicted a 40-year-old theory of how the brain controls impulsive behavior

Head trauma may increase the risk of developing schizophrenia, a new study says. The results show people who have suffered from a traumatic brain injury (TBI) are 1.6 times more likely to develop schizophrenia compared with those who have not suffered such an injury.

Researchers from the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital have conducted a study which has found striking brain similarities in bipolar disorder and schizophrenia.

The brains of older people are not slower but rather wiser than young brains, which allows older adults to achieve an equivalent level of performance, according to research undertaken at the University Geriatrics Institute of Montreal by Dr. Oury Monchi and Dr. Ruben Martins of the University of Montreal.

A new study testing alcohol’s effects on brain activity finds that alcohol dulls the brain “signal” that warns people when they are making a mistake, ultimately reducing self control.

Researchers in the Netherlands have been able to shed more light on how combat experiences change the brains of soldiers.

And finally, new research from MIT suggests that there are parts of our brain dedicated to language and only language, a finding that marks a major advance in the search for brain regions specialized for sophisticated mental functions.  And this week,new research makes the case that language is not a key part of thinking about numbers, but the key part, overriding other influences like cultural ones.

Weekly Round Up

Pathways within the brain can be strengthened by reading and language exposure

 Recent research shows that reading  boosts brain pathways and can actually affect understanding in nearly all school subjects – a great reason to encourage the reading habit in your children.

Scientists at the University of Michigan Health System have demonstrated how memory circuits in the brain refine themselves in a living organism through two distinct types of competition between cells. Their results, published  in Neuron, mark a step forward in the search for the causes of neurological disorders associated with abnormal brain circuits, such as Alzheimer’s disease, autism and schizophrenia.

The left and right halves of the brain have separate stores for working memory, the information we actively keep in mind, suggests a study published online yesterday by the Proceedings of the National Academy of Sciences.

Over time, and with enough Internet usage, the structure of our brains can actually physically change, according to a new study.

Bringing the real world into the brain scanner, researchers at The University of Western Ontario from The Centre for Brain and Mind can now determine the action a person was planning, mere moments before that action is actually executed.

And finally good news at last for coffee addicts.For years we’ve been told that caffeinated coffee was bad for us. It’s unhealthy and addictive, doctors warned. But as vindication for all who stuck by their energizing elixir, a new study published early online in the Journal of Alzheimer’s Disease,  shows that guzzling caffeinated coffee may actually be good for our brains. In fact, it may help keep Alzheimer’s at bay.  So enjoy that cuppa joe!