Category: Stroke

Weekly Neuroscience Update

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Childhood poverty impacted how much the two regions of the prefrontal cortex (as shown in orange circles) were engaged during emotion regulation. (Credit: University of Illinois at Chicago College of Medicine)

Childhood poverty impacted how much the two regions of the prefrontal cortex (as shown in orange circles) were engaged during emotion regulation. (Credit: University of Illinois at Chicago College of Medicine)

Childhood poverty and chronic stress may lead to problems regulating emotions as an adult, according to research published online in the Proceedings of the National Academy of Sciences.

New research shows that one of the brain’s fundamental self-protection mechanisms depends on coordinated, finely calibrated teamwork among neurons and non-neural cells knows as glial cells, which until fairly recently were thought to be mere support cells for neurons. The study, which has implications for understanding neurodegenerative diseases, stroke, and other nervous system disorders, adds to a growing body of evidence that glial cells are integral to brain function.

Researchers at higher education institutions have identified six proteins in spinal fluid that can be used as markers for Alzheimer’s disease. And another study suggests that older adults who don’t sleep well have more of the brain plaques that are hallmarks of Alzheimer’s.

Researchers from the Centre for Functional Resonance Imaging of the Brain (FMRIB) at the University of Oxford in the UK, say through monitoring patients’ brain waves while under anesthetic, they were able to pinpoint degrees of consciousness dependent on the doses of anesthetic administered.

Finally, this week, a new study from the UCLA School of Nursing shows that the body’s autonomic responses — the controls that impact such functions as blood pressure, heart rate and sweating — are weaker in people with obstructive sleep apnea but are even more diminished in women.

Weekly Neuroscience Update

Feeling happy or sad? Researchers have measured brain signals to accurately read emotions in individuals. (Credit: Karim S. Kassam et al PLOS ONE 10.1371/journal.pone.0066032)

For the first time, scientists at Carnegie Mellon University have identified which emotion a person is experiencing based on brain activity.

Pre-treatment scans of brain activity predicted whether depressed patients would best achieve remission with an antidepressant medication or psychotherapy, in a new study.

People who experience any stroke symptoms—but do not have a stroke—may also be more likely to develop problems with memory and thinking, according to new research published in the June 19, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.

And finally this week, a study, led by Royal Holloway University researcher Carolyn McGettigan, has identified the brain regions and interactions involved in impersonations and accents.

Weekly Neuroscience Update

A boxer utilizing the new concussion-detecting test A new tablet-based test is able to detect whether or not someone has sustained a concussion by analyzing their voice.

An international team of neuroscientists has described for the first time in exhaustive detail the underlying neurobiology of an amnesiac who suffered from profound memory loss after damage to key portions of his brain.

A fitness device created by Glasgow academics and designers helps stroke patients during their long road to recovery.

For anyone who has been affected by depression  it is no secret how devastating the disease can be for them and their families. But if the results from a small study published by a group at Germany’s Bonn University Hospital hold up, there could be a radical transformation in the treatment of depression.

An excess of the brain neurotransmitter glutamate may cause a transition to psychosis in people who are at risk for schizophrenia, reports a study from investigators at Columbia University Medical Center (CUMC) published in the current issue of Neuron.

New research finds that prisoners who are psychopaths lack the basic neurophysiological “hardwiring” that enables them to care for others.

The area of the brain that’s activated when people look at numerals such as “7” and “60” has been pinpointed by researchers. This spot is only about one-fifth of an inch across and consists of 1 million to 2 million nerve cells in the inferior temporal gyrus, the researchers said. The inferior temporal gyrus is known to be involved in the processing of visual information.

And finally this week, habitual liars’ brains differ from those of honest people, a study says. A University of Southern California team studied 49 people and found those known to be pathological liars had up to 26% more white matter than others

Weekly Neuroscience Update

Conceptual scheme of controlled release of ODN from a hydrogel composed of a CyD-containing molecular network by mechanical compression. (Credit: Image courtesy of National Institute for Materials Science)

A research group has succeeded in developing a gel material which is capable of releasing drugs in response to pressure applied by the patient.

New findings about how the brain functions to suppress pain have been published in the leading journal in the field Pain, by National University of Ireland Galway (NUI Galway) researchers. For the first time, it has been shown that suppression of pain during times of fear involves complex interplay between marijuana-like chemicals and other neurotransmitters in a brain region called the amygdala.

Researchers report that they have found a biological mechanism that appears to play a vital role in learning to read. This finding provides significant clues into the workings behind dyslexia — a collection of impairments unrelated to intelligence, hearing or vision that makes learning to read a struggle.

A new study suggests neural ‘synchrony’ may be key to understanding how the human brain perceives.

Sleep plays an important role in the brain’s ability to consolidate learning when two new potentially competing tasks are learned in the same day, research at the University of Chicago demonstrates.

New research for the first time explains exactly how two brain regions interact to promote emotionally motivated behaviors associated with anxiety and reward. The findings could lead to new mental health therapies for disorders such as addiction, anxiety, and depression.

Researchers have designed a decoded functional MRI neurofeedback method that induces a pre-recorded activation pattern in targeted early visual brain areas that could also produce the pattern through regular learning.

A new study conducted by monitoring the brain waves of sleeping adolescents has found that remarkable changes occur in the brain as it prunes away neuronal connections and makes the major transition from childhood to adulthood.

New research suggests that depression, even in children, can increase the risk of heart problems later in life. Teens who were depressed as children are far more likely than their peers to be obese, smoke cigarettes and lead sedentary lives, even if they no longer suffer from depression.

Alcohol consumption affects the brain in multiple ways, ranging from acute changes in behavior to permanent molecular and functional alterations. The general consensus is that in the brain, alcohol targets mainly neurons. However, recent research suggests that other cells of the brain known as astrocytic glial cells or astrocytes are necessary for the rewarding effects of alcohol and the development of alcohol tolerance.

New research published in The Journal of Neuroscience suggests that modifying signals sent by astrocytes, our star-shaped brain cells, may help to limit the spread of damage after an ischemic brain stroke.

The prefrontal cortex is a region of the brain that acts like a filter, keeping any irrelevant thoughts, memories and perceptions from interfering with the task-at-hand. In a new study, researchers have shown that inhibiting this filter can enhance unfiltered, creative thinking.

A new study suggests that depression results from a disturbance in the ability of brain cells to communicate with each other. The study indicates a major shift in our understanding of how depression is caused and how it should be treated.

 

 

Weekly Neuroscience Update

A run of poor sleep can have a potentially profound effect on the internal workings of the human body, say UK researchers.

As a bird sings, some neurons in its brain prepare to make the next sounds while others are synchronized with the current notes—a coordination of physical actions and brain activity that is needed to produce complex movements, new research at the University of Chicago shows. In an article in the current issue of Nature, neuroscientist Daniel Margoliash and colleagues show, for the first time, how the brain is organized to govern skilled performance—a finding that may lead to new ways of understanding human speech production.

Deep brain stimulation has helped people with severe obsessive-compulsive disorder, and new research begins to explain why. A Dutch study appearing in the Feb. 24 online issue of the journal Nature Neuroscience found the procedure essentially restored normal function in a part of the brain called the nucleus accumbens.

Researchers have identified a possible treatment window of several years for plaques in the brain that are thought to cause memory loss in diseases such as Alzheimer’s. The Mayo Clinic study is published in the Feb. 27 online issue of Neurology.

Though it’s most often associated with disorders like diabetes, Harvard researchers have shown how the signaling pathway of insulin and insulin-like peptides plays another critical role in the body – helping to regulate learning and memory.

Researchers in Scotland and Germany have discovered a molecular mechanism that shows promise for developing a cure for Huntington’s Disease (HD).

Some people do not learn from their mistakes because of the way their brain works, according to research led by an academic at Goldsmiths, University of London. The research examined what it is about the brain that defines someone as a ‘good learner’ from those who do not learn from their mistakes.

Scientists from the University of Oxford say they have discovered how the brain protects itself from damage that occurs in stroke.

A team of French researchers has discovered that the human brain is capable of distinguishing between different types of syllables as early as three months prior to full term birth. 

Weekly Neuroscience Update

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When selecting a video game to play, opting to turn on your Wii may provide a different experience than playing your Xbox, according to a study from Mississippi State University.

Excessive alcohol use accounts for 4% of the global burden of disease, and binge drinking particularly is becoming an increasing health issue. A new review article published Cortex highlights the significant changes in brain function and structure that can be caused by alcohol misuse in young people.

Working with patients with electrodes implanted in their brains, researchers have shown for the first time that areas of the brain work together at the same time to recall memories. The unique approach promises new insights into how we remember details of time and place.

Researchers at the University of Glasgow are hoping to help victims of stroke to overcome physical disabilities by helping their brains to ‘rewire’ themselves.

Keeping active can slow down the progression of memory loss in people with Alzheimer’s disease, a study has shown.

Neuroscientists have released the results of a new study that examines how fear responses are learned, controlled, and memorized. They show that a particular class of neurons in a subdivision of the amygdala plays an active role in these processes.

Neuroscience researchers from Tufts University have found that our star-shaped brain cells, called astrocytes, may be responsible for the rapid improvement in mood in depressed patients after acute sleep deprivation. This in vivo study, published in the current issue ofTranslational Psychiatry, identified how astrocytes regulate a neurotransmitter involved in sleep. The researchers report that the findings may help lead to the development of effective and fast-acting drugs to treat depression, particularly in psychiatric emergencies.

UC Berkeley neuroscientists have found that the slow brain waves generated during the deep, restorative sleep we typically experience in youth play a key role in transporting memories from the hippocampus – which provides short-term storage for memories – to the prefrontal cortex’s longer term “hard drive.”

Researchers have found altered connectivity in the brain network for body perception in people with anorexia: The weaker the connection, the greater the misjudgement of body shape.

A group of scientists planning to map all the major connections in the human brain began studying their first test subjects in August. The $30 million Human Connectome Project will trace the main neural pathways that link the roughly 500 major regions in the brain, illuminating how biological circuitry underlies our mental functions. MRI scans of 1,200 people, including 300 pairs of twins, will be used to compile an atlas of communication routes throughout the brain. The resulting blueprint will also reveal how brain connectivity varies from person to person.

Weekly Neuroscience Update

Mind wandering may increase creative thinking, according to a new international study.

Simple mental activity such as reading, writing, playing games and doing puzzles may protect brain health in old age, according to a new study.

Reduced production of myelin, a type of protective nerve fiber that is lost in diseases like multiple sclerosis, may also play a role in the development of mental illness, according to researchers at the Graduate School of Biomedical Sciences at Mount Sinai School of Medicine.

A small molecule known to regulate white blood cells has a surprising second role in protecting brain cells from the deleterious effects of stroke, Johns Hopkins researchers report.

Scientists have revealed the minutely detailed pain map of the hand that is contained within our brains, shedding light on how the brain makes us feel discomfort and potentially increasing our understanding of the processes involved in chronic pain.

People with Parkinson’s disease benefit from exercise programs on stationary bicycles, with the greatest effect for those who pedal faster, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA).

A new method to study widespread networks of neurons responsible for our memory has been discovered by scientists from the Max Planck Institute for Biological Cybernetics.

The first study to estimate rates of traumatic brain injury (TBI), without relying on official figures, suggests the worldwide incidence of TBI could be six times higher than previously estimated.

MRI shows changes in the brains of people with post-concussion syndrome (PCS), according to a new study published online in the journal Radiology. Researchers hope the results point the way to improved detection and treatment for the disorder.

photo credit: pamlau.com via photopin cc

Weekly Neuroscience Update

Image: Pixmac.com

Gym-style exercise may improve not only general health in middle age, but also brain function, according to new research.

Researchers at Oregon Health & Science University have discovered that blocking a certain enzyme in the brain can help repair the brain damage associated with multiple sclerosis and a range of other neurological disorders.

Researchers at the University of Minnesota’s Center for Magnetic Resonance Research (CMRR) have found a small population of neurons that is involved in measuring time.

Two proteins have a unique bond that enables brain receptors essential to learning and memory to not only get and stay where they’re needed, but to be hauled off when they aren’t, researchers say.

Scientists have discovered that the brain circuits we engage when we think about social matters, such as considering other people’s views, or moral issues, inhibit the circuits that we use when we think about inanimate, analytical
things, such as working on a physics problem or making sure the numbers add up when we balance our budget. And they say, the same happens the other way around: the analytic brain network inhibits the social network.

Lund University researchers plan to use optogenetics to stimulate neurons to release more dopamine to combat Parkinson’s disease.

A new finding could lead to strategies for treating speech loss after a stroke and helping children with dyslexia. New research links motor skills and perception, specifically as it relates to a second finding – a new understanding of what the left and right brain hemispheres “hear.”

UCLA researchers have for the first time measured the activity of a brain region known to be involved in learning, memory and Alzheimer’s disease during sleep. They discovered that this region, called the entorhinal cortex, behaves as if it’s remembering something, even during anesthesia–induced sleep — a finding that counters conventional theories about sleep-time memory consolidation.

Weekly Round-Up

 

Why do we love to learn about the brain?

In today’s weekly round-up..how patients with signs of dementia may improve their brain health with exercise, how brain cooling could aid stroke recovery, how brain scans can predict the likely success of giving up smoking, and finally why learning about the brain can become addictive. 

 According to researchers, just 40 minutes of moderate exercise in pensioners physically grows the brain and helps people enhance their brain power. It was found that regular exercise programs work on people already showing signs of dementia and loss of brain function. Meanwhile, McGill’s Dr Véronique Bohbot, believes that spatial strategies can reduce risk of dementia.

Cooling the brain of patients who have suffered a stroke could dramatically improve their recovery, according to research at the Centre for Clinical Brain Sciences at the University of Edinburgh.

Were you one of the many who made a New Year’s Resolution to give up smoking?  Brain scans showing neural reactions to pro-health messages can predict if you’ll keep that resolution to quit smoking more accurately than you yourself can. That’s according to a new study forthcoming in Health Psychology.

Finally, in the Psychology Today blog, Dr David Rock asks the question “why is it so engaging, almost addictive, to learn about how your brain functions” and concludes that it is “because it makes life feel richer, and enables us to achieve our intentions”.

What better way to end this week’s round-up! May the learning continue…