Weekly Neuroscience Update

*Schematic representation of the social perception and ventral face perception pathways in the brain.*
*Credit: Imaging Neuroscience (2026).*

Newborn babies are naturally drawn to faces, a trait that helps them bond with their mothers and other caregivers. New Yale research has now found that the functional brain network involved in processing dynamic faces in adults can be observed as early as the third trimester of pregnancy.

Researchers have developed an AI model that analyzes a person’s DNA to better identify genetic risk factors for stroke, paving the way for more personalized risk assessments.

A new study published in the American Journal of Psychiatry found that deep brain stimulation (DBS) for treatment-resistant depression led to sustained improvement by stimulating specific brain connections. It is the largest multicohort study on patients receiving subcallosal cingulate DBS. Additionally, findings reported in Imaging Neuroscience indicate that the brain pathway for perceiving socially engaging faces can be detected in the womb, highlighting early brain network development.

Therapy targeting the immune system’s B cells might offer better odds against relapses in the early stages of multiple sclerosis (MS), a new study reports. The findings were published in the journal Neurology Open Access.

Adults who averaged fewer than 5,000 steps a day were later diagnosed with dementia, Parkinson’s disease or stroke at almost twice the rate of those averaging more than 12,000 steps, according to a new study presented at the 151st Annual Meeting of the American Neurological Association (ANA).

Children consuming more ultraprocessed foods exhibit heightened brain responses to appealing food images, which are associated with increased body fat a year later.

Previous studies have suggested that body posture and movement can influence emotions. Now researchers have extended this line of research by showing that when people perform the same “depressed” body movements, their brain responses differ depending on the level of their depressive symptoms.

Clinician-scientists hope to expand the use of blood-based biomarker tests for traumatic brain injury (TBI) to improve identification and escalation of care for patients whose diagnosis otherwise might be missed.

In a recent study, researchers investigated the impact of maintaining physical activity and blood pressure on cognitive abilities over a 14-year period. They tracked participants’ daily step counts and blood pressure, followed by computerized tests assessing attention, focus, and self-control. Results indicated that increased daily steps correlated with improved performance in cognitive tests.

A major review of more than 2 million people has found current smokers face a higher risk of dementia.

Researchers at Karolinska Institutet and their collaborators have identified two previously unknown forms of the protein amyloid-beta that may contribute to the development of Alzheimer’s. The study, published in Nature Communications, also shows that a protein previously discovered by the researchers can counteract the formation of these harmful forms, suggesting a potential new treatment approach.

Scientists have discovered that serotonin, a brain chemical best known for its role in mood and mental health, also helps regulate attention.

Three distinct brain biotypes exist in children who have attention-deficit/hyperactivity disorder, anxiety disorder or both, a new Stanford Medicine–led study has shown. The discovery could help clarify a confusing picture of two of the most common mental health conditions of childhood, which often overlap. Each biotype is characterized by malfunctions in a specific set of brain circuits, according to the study, published in Nature Mental Health.

A naturally occurring molecule that helps the brain clear away damaged blood cells could open the door to new treatments for one of the deadliest forms of stroke, research led by University of Manchester scientists suggests.

A study of more than 1,800 older Australians found that people who had experienced lifetime trauma were more likely to have mild cognitive impairment (MCI) or dementia and performed worse on working memory and executive function tests. However, stressful events experienced in the previous six months were not associated with poorer cognitive outcomes.

A recent review has revealed type 2 diabetes significantly raises the risk of developing Alzheimer’s disease.

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Researchers studied brain scans of 386 individuals with Major Depressive Disorder to observe changes in brain connectivity during the initial weeks after starting a placebo or one of two antidepressants. Their findings highlight both common changes across treatment groups and specific patterns related to the antidepressant treatments.

Scientists have identified a key mechanism that helps determine the length of myelin, the protective coating that surrounds many nerve fibers and allows signals to travel efficiently through the nervous system.

A study from Lund University published in Nature Neuroscience reveals that normal aging and Alzheimer’s affect brain communication differently, with distinct patterns of alterations. Notably, changes in Alzheimer’s patients occur early, prior to the onset of cognitive symptoms.

Researchers have developed 3D “mini-brains” they hope will help speed up the search for drug treatments for multiple sclerosis (MS).

A study reveals that childhood abuse affects brain structure, specifically cortical thickness, surface area, and subcortical volume, with more significant effects observed in young women. This research is the largest to investigate the neurobiological impacts of childhood maltreatment in a diverse, global population.

A graphene-based brain sensor could help doctors watch the hidden damage unfolding during a stroke in real time, offering new hope of preventing devastating brain injuries before they become irreversible.

Researchers at the University of Osaka found that stimulating the primary somatosensory cortex and the insular cortex simultaneously may enhance artificial touch sensations, producing effects beyond typical tingling or numbness. The study is published in Brain Stimulation.

Inflammatory conditions in the brain, including traumatic brain injury and degenerative diseases like Alzheimer’s, could be targeted with an existing drug thanks to new research that shows it can work in brain cells.

The largest genetic study of cognition to date has been published, involving nearly half a million people of European ancestry. This provides a new understanding of the genetic factors that shape cognitive differences and can help us better understand certain health conditions, including neurodevelopmental conditions.

Isolated REM sleep behavior disorder (iRBD) is an early indicator of brain changes linked to Parkinson’s disease or dementia with Lewy bodies, often emerging years prior to diagnosis.

A new study finds that adults with attention-deficit/hyperactivity disorder (ADHD) face a significantly higher risk of developing dementia or mild cognitive impairment later in life. The research, published in JAMA Psychiatry, also found that people who carry a higher genetic risk for ADHD face a greater chance of cognitive decline even without a documented diagnosis.

Researchers have led an international scientific team studying how a traumatic brain injury caused by a severe blow to the head affects the brain’s long-term response to subsequent stressful situations.

A long-term study of more than 4,500 older adults reveals that individuals who are overweight or obese when diagnosed with dementia exhibit a significantly lower risk of death than those of normal weight. Rigorous epidemiological modeling suggests this survival advantage is not merely an artifact of statistical bias, underscoring the critical protective role of nutrition and metabolic reserves in neurodegenerative decline.

Older people with autism are more likely to develop symptoms of Parkinson’s disease, a new study says.

A large-scale international study offers new insights for understanding Alzheimer’s disease and developing future treatments. The University of Exeter–led PROTECT study was part of the research, led by Vrije Universiteit Amsterdam and published in Nature, which sheds clearer light on the role of immune cells within the brain, as well as several specific neuronal cell types.

There is not enough evidence to determine whether testosterone helps with thinking and memory in midlife women, even though it is often prescribed in the UK, according to a recent study.

Mayo Clinic researchers have detected measurable changes in the brain within 18 minutes of deep brain stimulation (DBS) in people with drug-resistant epilepsy, a finding that could eventually help clinicians personalize treatment without waiting months to determine whether stimulation settings are effective. The study was recently published in iScience.

Finally this week, new study suggests that brains in healthy older adults may cope better with a lack of sleep than those in younger adults.

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Cinematic neuroscience laboratory with illuminated brain scan

A new study by neuroscientists at MIT’s Picower Institute for Learning and Memory shows how the brain encodes information throughout the decision-making process to keep options clearly in mind and ensure that chosen and unchosen options are remembered.

A clinical trial has shows that high-frequency spinal cord stimulation can reduce pain and improve sensory function in people with treatment-resistant diabetic neuropathy.

Education, intellectually stimulating work and an active lifestyle help preserve cognitive abilities in adults over 65 and lead to more effective verbal expression and stronger cognitive performance. But there is another important factor: emotions. The way we recognize and interpret them can significantly influence the efficiency of cognitive processes as we age.

A new UCLA study has found a connection between how quickly the brain ages and the bacteria and chemical byproducts found in the gut, offering a clue to what drives brain aging long before symptoms appear.

Scientists have identified over 830,000 brain immune cells, including a protective subtype of microglia that increases during Alzheimer’s disease. These cells, influenced by the TREM2 pathway, assist in removing harmful substances from the brain, offering a new approach for therapies that aim to enhance the brain’s innate immune defences instead of just targeting amyloid plaques.

A recent study suggests that slow electrical rhythms traveling along individual nerve fibres may do more than reflect brain activity: They may help coordinate communication between key memory centres in the hippocampus.

New research from Carnegie Mellon University reveals that dendritic spines—the tiny structures that help brain cells communicate and form memories—don’t fit neatly into a few categories. Instead, they display a continuous range of shapes, offering new insight into learning, development and neurological disease.

People living with a severe form of asthma show subtle differences in the structure of their brains compared with people whose asthma is well controlled, according to new research presented at the European Respiratory Society Congress.

Researchers have discovered that sitting on Japanese Igusa mats, made from rush grass, enhance concentration and engagement in the brain while reducing tension and anxiety in users. With centuries of use in Japan, the research aims to validate its health benefits and highlight the value of this traditional material.

New research indicates that people with invasive cancer face an elevated risk of experiencing a stroke, especially in the first few months after diagnosis and if they have certain types of cancer. The findings are published in Cancer.

A recent study compared eye-tracking data from 368 adult readers with predictions from over 400 neural network models, revealing that large language models (LLMs) struggle to predict human cognitive challenges in contextualizing words, despite being accurate in word recognition speed.

Researchers have found a method to predict the onset of symptoms in individuals at high risk for Alzheimer’s, aiding physicians in determining the appropriate timing for preventive treatments.

A study of more than half a million adults has found that higher levels of exhaled carbon monoxide were associated with a lower risk of Parkinson’s disease. The findings, published in JAMA Neurology, uncover a possible new explanation for the consistently lower rates of Parkinson’s among smokers that have long puzzled scientists.

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Researchers examined changes in brain activity during cognitive tasks before and after acute aerobic exercise in healthy young and older adults. The study is published in the Journal of Magnetic Resonance Imaging.

A new study indicates that the brain’s response to breathing is not uniform; instead, the unique characteristics of each breath correlate with neural activity related to cognition, emotion, and memory. This suggests that the brain monitors subtle variations in breathing, with changes in inhale and exhale timing and intensity reflected in distinct neural patterns, highlighting a more nuanced link between breathing and brain function than previously understood.

Early initiation of statins after diagnosis of type 2 diabetes was associated with a lower risk of dementia, according to a study presented at ESC Congress 2026 and published in The Lancet Regional Health – Europe.

Immune cells that normally protect the body from damage by attacking foreign or infected cells are found in the brains of patients with Alzheimer’s disease and related disorders at much higher levels than in healthy brains. The cells appear to contribute to neurodegeneration, but where they come from and how they are primed to accumulate in the brain was not known.

A new study has used a type of machine learning called a neural network to reveal how different kinds of training can change how learning happens—both in machines and in living brains.

The influence of the hormone progesterone on mood is well known. Now, researchers have shown how higher levels of progesterone during the menstrual cycle are linked to less distinct patterns of activity in areas of the brain involved in controlling emotions.

Regular aerobic exercise—the kind that gets your heart pumping—can improve important thinking skills called executive functions, and the benefits appear especially strong for women after menopause, according to Rutgers researchers.

Musicians don’t just learn movement sequences faster; they predict what’s coming next sooner, according to new research that also found newly formed motor memories can be disrupted by seeing different visual sequences shortly after learning. The work is published in the journal Psychological Research.

A study by the University of Eastern Finland found that quality of life in people with multiple sclerosis (MS) is strongly associated with walking performance and functional capacity.

The neuroactive potential of bacteria living in the human gut is associated with levels of key chemicals in the brain, according to a new study published in Molecular Psychiatry. The research team found that microbial pathways involved in producing and breaking down neuroactive compounds were associated with levels of GABA and glutamate in specific regions of the human brain.

A study conducted at the University of Helsinki indicates that the total number of people with dementia will grow significantly in the coming years, and the number of those living at home may even more than double after 2018.

A new study reveals that migraine may leave a biological pattern throughout the body, traces of which can be identified by artificial intelligence. Researchers used AI to analyze information gathered from more than 43,000 participants during a countywide health survey.

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Credit: *European Journal of Nuclear Medicine and Molecular Imaging* (2026).

Researchers studied how autism manifests in the brain by examining the dopamine system, energy use, and communication between brain regions in 60 adults, using three advanced brain-scanning techniques. They found a higher number of dopamine D2 receptors in autistic individuals compared to neurotypical individuals, indicating a significant role of the dopamine system in autism.

Deep brain stimulation, or DBS, may help improve speech and swallowing problems caused by traumatic brain injury (TBI), according to a new study published in Nature Communications.

As people age, cognitive functions generally decline, but language skills often remain intact or even improve unless affected by conditions like stroke or dementia. A recent study has found that older adults exhibit similar neural activity in the language-processing network as younger adults during language tasks, although activation patterns in the executive control tasks network differ significantly between the two age groups.

Research from the University of East Anglia shows how our memories change with age and why specific details associated with past events can fade over time.

Scientists have identified a previously unknown aspect of schizophrenia that offers a new way to understand how the disorder affects large-scale brain coordination. In a new study, published in the journal Translational Psychiatry, researchers introduced a method for measuring how brain networks maintain balanced activity and recover when that balance is disrupted.

Findings from a new study suggest that the trickle of neurons created in the adult hippocampus could be instrumental in preventing depression. Most of the brain’s 100 billion neurons are created before birth.

A short workout or a nap can help protect memory after a sleepless night, a recent study has found. Researchers found people who either completed 20 minutes of moderate-to-vigorous exercise or took a 90-minute nap performed about 22% better on memory tests after 30 hours without sleep than those who did neither.

A study published in Neuron has identified the brain mechanisms that help us work out whether the consequences we experience are caused by our own actions or by circumstances beyond our control.

A new study suggests that gut bacteria may send different biological signals in Parkinson’s disease. The findings add to growing evidence that changes in the gut could be linked to Parkinson’s disease and may eventually help researchers identify new underlying mechanisms for the condition.

Scientists have found that a pattern of brain atrophy visible on MRI could help predict how quickly people with early-onset Alzheimer’s disease progress from mild cognitive impairment to dementia.

Some people with epilepsy experience delusions, hallucinations, paranoia and confusion after a seizure. While these episodes usually last only days, a new study led by researchers suggests they may place patients at significantly higher risk of developing psychiatric disorders later.

The brain may “tag” experiences during learning to better consolidate memories of them during sleep, according to a study published in the journal PLOS Biology by Dan Denis from the University of York, United Kingdom, and colleagues.

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Microwire locations, task, ripple characteristics and increased co-firing during co-ripples at all recording separations. Credit: *Nature Neuroscience* (2026).

Researchers have discovered that high-frequency brain waves, known as ripples, may facilitate synchronization between distant brain regions during working memory tasks, highlighting their potential role in coordinating neural activity across long distances during cognitive processes.

Having normal blood pressure, no diabetes, and not smoking from age 48 to 68, are associated with nearly 13 additional years on average of dementia-free life, a new study shows.

Childhood epilepsy is linked to significantly poorer exam grades and long-term educational attainment, with the lowest levels of academic achievement among those whose neurological disorder started when they were very young, finds a large, long-term Danish study published online in the Journal of Neurology Neurosurgery & Psychiatry.

In a paper appearing in Nature Communications, researchers show how music produces distinct patterns in the regions of the brain associated with imagination and meaning, similar to those prompted by spoken narratives.

A new study suggests that Alzheimer’s disease may be detected by brain imaging more than seven years earlier than previously assumed. The study suggests that the gold standard for imaging in Alzheimer’s disease (amyloid-PET) has not been sensitive enough to detect early brain processes associated with the disease, such as the accumulation of amyloid plaques in the brain. The researchers found signs of Alzheimer’s at least seven years before plaques became visible.

A person’s sleep patterns could be an early sign of Alzheimer’s disease, a new study says. A greater number of micro-awakenings during sleep is linked to a greater genetic risk for Alzheimer’s, researchers report in the journal Sleep.

People living with severe mental illness face a substantially higher risk of dementia throughout adulthood, as well as a significantly elevated risk of stroke in early and middle adulthood, according to a large new study based on health records from Catalonia, Spain. The findings, published in European Neuropsychopharmacology, suggest that physical health risks linked to severe psychiatric conditions emerge much earlier than many clinicians may expect, underscoring the need for general health care to be more integrated into mental health care.

A new study published in Brain Stimulation shows that the brain’s ongoing activity before stimulation can predict much of this variability, offering a path toward more reliable neuromodulation therapies.

A new AI model analyzes routine sleep study data to reveal patients’ long-term health risks, such as heart disease and cognitive decline. The study indicates that standard medical tests hold more physiologic information than typically recognized, with AI uncovering significant patterns in sleep data that traditional measures miss.

Published in the Journal of Cognitive Enhancement, a new study found six one-minute bouts of stair climbing improved people’s cognitive health.

Researchers have identified a possible biological marker linked to severe suicidal thoughts. The finding, published in The British Journal of Psychiatry, may also help explain why some people recover from these thoughts, opening a new path for research into resilience and suicide prevention.

A research team has demonstrated that transcranial direct current stimulation (tDCS) significantly improves depression and apathy in patients with Parkinson’s disease.

A recent study suggests that a single 20-minute session of noninvasive deep brain stimulation, paired with mindful breathing, may strengthen the brain’s response to reward and reduce anxiety. Changes in reward-related brain activity remained detectable for approximately one week after the session.

Researchers have created an AI-based method to produce detailed maps revealing how different brain areas age and their correlation with cognitive function over a lifetime.

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Credit: *Proceedings of the National Academy of Sciences* (2026)

Scientists have developed a computer model of the human cortex that links its microscopic chemistry to its brain-wide patterns of activity, providing new evidence that regional differences in receptor density help shape how activity and information move across the brain.

An international consortium has established the first consensus-based framework and standardized taxonomy for vocal biomarkers.

A novel AI model can use information collected during routine sleep studies to identify patients’ long-term health risks, according to a new study published in Nature Communications. Developed by a multidisciplinary research team, the model uncovered hidden sleep patterns linked to risks including heart disease, cognitive decline and death.

Experiencing severe stress during childhood can make a person more vulnerable to anxiety, depression and other mood disorders when faced with hardships as an adult.

A new study reveals that during deep REM sleep, the human brain shifts its sensory processing focus from external sounds to internal cardiac signals. As responsiveness to outside noise decreases, the processing of these internal signals increases. The researchers created an audio-cardio index to measure this neural shift, providing a new physiological marker for evaluating altered states of consciousness.

Researchers have created an energy-efficient AI model that mimics hippocampal brain mechanisms, enabling it to construct cognitive maps, perform stochastic computations, and solve complex planning tasks efficiently.

A new mathematical model that reproduces the relapsing-remitting pattern of multiple sclerosis (MS) offers scientists a tool to better understand how the disease progresses. The model, developed by QUT researchers from the School of Mathematical Sciences, is published in the Journal of the Royal Society Interface.

The first U.S. clinical trial evaluating psilocybin-assisted therapy in military veterans with treatment-resistant post-traumatic stress disorder (PTSD) has demonstrated significant safety and clinical efficacy.

A new study in Nature Genetics reveals a detailed map of brain immune cells involved in Alzheimer’s disease, highlighting a protective subtype that grows as the disease advances and identifying the molecular pathway that helps these cells defend the brain, with potential implications for future therapies.

A clinical trial, has found that oral semaglutide significantly reduces heavy drinking days, daily cravings, and alcohol-related problems in adults with moderate-to-severe Alcohol Use Disorder (AUD).

Scientists have found that the human brain processes low-frequency infrasound through a unique mechanism where acoustic waves bypass auditory hair cells and activate inner ear support cells, generating electric fields that stimulate different nerve pathways, causing infrasound to be felt more as a physical sensation than an audible sound.

Scientists have uncovered how a major Parkinson’s disease gene disrupts the brain’s most vulnerable dopamine-producing neurons before detectable neuronal loss. The study findings are published in Nature Communications.

A compound produced by bacteria in many people’s digestive tracts increases the risk of developing Alzheimer’s disease and speeds cognitive decline in dementia patients, making it a potential target for a treatment that could reduce Alzheimer’s risk, according to a new study published in Nature Communications.

Researchers have found that depression is associated with smaller volume in a specific part of the hippocampus, a brain region essential for learning and memory.

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*Credit: Biological Psychiatry / Volpi et al.*

A new brain imaging study published in eBioMedicine, provides the strongest evidence to date that long COVID is associated with injury to dopamine-releasing neurons in the brain—a finding that may explain symptoms such as lack of motivation due to fatigue, slowed movement and memory difficulties, and could open the door to new treatment strategies.

New research shows that sleep disorders are associated with structural changes in brain regions involved in attention, motivation and decision-making.

A new study reports that sensors can accurately monitor disease progression in patients with Parkinson’s, addressing the limitations of wearable technologies. The research, conducted by scientists from the UK Dementia Research Institute, aims to create a zero-burden method for tracking movement changes in affected individuals

Drugs commonly used for weight loss, known as GLP-1 receptor agonists, have been found to reduce the key symptoms of binge eating disorder, in a new review of evidence led by University College London (UCL) researchers.

Scientists at Trinity College Dublin have discovered that, for a short period of around one to two seconds, the brain can begin following a new conversation before it has fully let go of the previous one. The findings challenge the long-held view that we can only focus on one speaker at a time.

People with dementia, mild cognitive impairment, alcohol addiction or psychiatric disorders such as schizophrenia show increased brain ageing, each in specific patterns within the brain, according to a study published in PLOS Medicine.

Individuals with psychiatric conditions have less flexibility in their brain network dynamics, as found in a new Rutgers study. The brain is made up of networks that adapt and reorganise to handle changing cognitive and emotional needs. This ability to reconfigure supports how we manage our thoughts and behaviours.

A new neuroimaging study published in the journal Brain Imaging and Behavior provides some of the first evidence that strengthening your brain health through daily habits rewires its physical architecture

Researchers have conducted one of the most comprehensive studies on how the autistic brain processes faces. Some hallmark characteristics of autism include tendencies to avoid looking at others’ faces and to make less eye contact. The research is published in the journal Nature Mental Health.

A new study highlights “gut jet lag”, the desynchronization between host biological clocks and gut microbiota rhythms during long-haul travel.

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*Credit: Jeffrey Parr/University of Southern Mississippi*

New research indicates that athletes with ADHD need even more scrutiny when head injuries are involved.

Scientists have made progress in finding better pain treatments with a new study aimed at reducing the addictive effects of morphine. They found that activating a dopamine receptor called D4 boosts morphine’s pain-relieving effects and helps prevent tolerance.

Prefrontal transcranial pulse stimulation is associated with antidepressant effects, according to a study published in JAMA Network Open

Cerebrovascular disease can cause serious problems if not treated quickly, but it’s hard to spot before symptoms show up. Researchers have developed an AI technology that analyses daily activities and environmental data from older adults to identify signs of cerebrovascular disease risk based on small changes in their home lives.

Researchers have developed a small graphene-based sensor to noninvasively measure dopamine in artificial tears, enabling rapid neurodegenerative screening.

The Consortium for Biomedical Research and Artificial Intelligence in Neurodegeneration (C-BRAIN) has launched three open-source AI tools. These tools act as team members in biomedical research, analysing global neuroscience literature, identifying patterns in hidden data, and providing objective peer reviews to accelerate the development of life-saving treatments.

A retrospective cohort study of 19,824 NFL players confirms that professional football veterans face a fourfold increase in neurodegenerative mortality, including a 3.8-fold surge in all-cause dementia and Parkinson’s disease.

A study in Neurology found that people with early-onset dementia had lower work productivity up to 15 years before they were diagnosed, with variations by type of dementia. Early-onset dementia refers to anyone under 65 diagnosed with dementia. The study only shows a link between early-onset dementia and reduced productivity, not that one causes the other.

A research team created a brain implant that can modulate neural activity with temperature, offering new opportunities for brain-computer interfaces and neurological treatments.

New research has used advanced EEG-fMRI tracking to show that the brain doesn’t operate as a single process. Instead, the human connectome manages multiple separate, asynchronous streams of information processing that happen simultaneously, providing new insights into clinical neuro-diagnostics and cognitive complexity.

A new study has introduced a novel machine learning method for analysing how the brain organises complex behaviours, offering fresh evidence that neural activity is built from reusable “building blocks.” The study is published in Neuron.

Scientists have conducted a study that enhances the understanding of the brain’s neuromodulators—acetylcholine, dopamine, and serotonin. The research integrates advanced experimental measurements with detailed computational models of the brain, demonstrating how these chemical messengers influence the electrical activity of numerous neurons in the developing brain.

Exposure to high temperatures during pregnancy and early infancy is linked to slower thalamic growth in childhood, as indicated by research from the Barcelona Institute for Global Health.

A new study has found that older adults who participated in a structured, 2-year healthy lifestyle program saw a significant improvement in memory and thinking skills, approximately 55% greater per year, compared with those who received only general health advice.

Research has shed new light on the biological basis of schizophrenia by directly measuring synaptic connections in the human brain using specialised positron emission tomography (PET) imaging.

A major study involving over 214,000 older adults from 14 countries shows that common risk factors for dementia—like low education, high blood pressure, and smoking—differ greatly between countries. This indicates that a single approach to prevention won’t be effective everywhere.

Natural plant compounds called polyphenols, found in foods such as berries, tea, cocoa, coffee, and extra-virgin olive oil, may positively influence biological processes associated with Alzheimer’s disease and nerve cell loss, claims a recent review.

A recent study found that poor sleep affects brain communication in adults, particularly highlighting that older women with poor sleep exhibited abnormal connectivity between the Default Mode Network and the Frontal Parietal Network. This over-communication correlated with worse memory performance and resembled brain patterns observed in early stages of Alzheimer’s disease.

Rare DNA changes are most strongly linked to cognition in early childhood, but the link fades as children age, while common DNA changes show stronger links later in childhood, a new study finds.

Researchers have demonstrated a novel AI model that can predict which DNA molecules bind with which other DNA molecules. Providing a more thorough understanding of these hypercomplex binding relationships has utility in applications ranging from biomedical diagnostic tools to DNA computing.

A study revealed that heightened amygdala activity in adolescents viewing emotional faces can forecast their social health two years later, showing that for girls it indicated greater peer engagement, while for boys it indicated less.

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Regional overlap between dimensional associations between conduct problems and brain structure (current study) and case-control differences in conduct disorder. Credit: Journal of the American Academy of Child & Adolescent Psychiatry (2026).

Conduct problems—including persistent rule-breaking, aggression, irritability and difficulty following school rules—are associated with small but widespread differences in brain structure, according to a major international study of more than 14,000 children and adolescents.

New research has discovered subtle but widespread differences in the brain’s communication networks in people with bipolar disorder, offering new insight into how illness severity and treatment may relate to brain wiring.

A recent study has identified hidden pathways through which parental DNA influences a child’s life, presenting a framework that separates direct genetic inheritance from parents’ environmental impacts, known as “genetic nurture.” By analysing data from over 30,000 multigenerational families, researchers found that the domestic environment shaped by parental DNA can affect traits such as height, weight, and academic ability that rival direct inheritance.

A study of 2,044 older Japanese adults revealed that lower vitamin C levels in blood plasma are associated with reduced gray matter volume and connectivity in the brain’s default mode network.

Researchers have discovered unique brain activity patterns in individuals with depression, shedding light on the persistent nature of depressive symptoms. Their study, used advanced neuroimaging and mathematical modelling to analyse brain transitions between states, indicating that depression may involve “brain-state entrapment,” whereby the brain tends to favour certain activity patterns and struggles to shift away from them.

Adolescents who spend at least two hours a day on social media are more likely to experience depressive symptoms and poorer well-being, with the strongest effects in early adolescence, according to new research.

A new study challenges the belief that teenage risk-taking is due to excess dopamine, finding instead that it stems from low baseline dopamine levels. Analysing data from over 800 adolescents, researchers discovered that those with the lowest reward biology use substances like alcohol and cannabis as a way to stimulate their underactive brains. As their dopamine systems mature into adulthood, their experimentation with substances significantly decreases.

New research suggests that reinforcing the body’s natural daily rhythms to improve sleep could help the brain recover after a stroke.