Weekly Neuroscience Update

Credit: Molecular and Cellular Biochemistry (2025)

A new review highlights five major ways microplastics can harm the brain, raising concerns that they may worsen neurodegenerative diseases like Alzheimer’s and Parkinson’s. These tiny particles can trigger inflammation, disrupt the blood–brain barrier, generate oxidative stress, impair mitochondria, and damage neurons.

Researchers have mapped how brain networks differ in individuals at Clinical High Risk (CHR) for psychosis, providing a new perspective on the mechanisms underlying the disease onset.

A new study found that variations in the brain’s insulin receptor network affect how women respond to early-life adversity. This effect has a lesser impact in men, suggesting there is a sex-specific process at play.

Dopamine neurons—the cells that drive reward and motivation while we’re awake—become surprisingly active during nonrapid eye movement sleep right after we learn something new.

The human brain processes spoken language in a step-by-step sequence that closely matches how large language models transform text. Using electrocorticography recordings from people listening to a podcast, researchers found that early brain responses aligned with early AI layers, while deeper layers corresponded to later neural activity in regions such as Broca’s area.

In a new leap for neurobiology and bioelectronics, scientists have developed a wireless device that uses light to send information directly to the brain—bypassing the body’s natural sensory pathways.

Young children exposed to unusually high temperatures are less likely to reach basic developmental milestones in literacy and numeracy. Analyzing data from over 19,000 children across multiple countries, the study found that average maximum temperatures above 86 °F were associated with measurable declines in early learning outcomes.

new study shows that dance can be beneficial in halting the cognitive decline associated with Parkinson’s disease and, for some participants, they even showed signs of improvement.

A research team has developed a new AI foundation model that creatively solved the problem of the “label data shortage,” regarded as the biggest challenge in deep learning-based brain signal analysis. This technology is designed to self-learn brain signals and is gaining attention for its ability to deliver high accuracy with very small amounts of labels.

Semaglutide medications like Ozempic and Wegovy can help lower the risk of heart and metabolic diseases in people with schizophrenia spectrum disorders, according to a new study.

A newly discovered biological signal in the blood could help health care teams and researchers better understand how children respond to brain injuries at the cellular level, according to research in the Journal of Neurotrauma.

Neuroscientists have developed a first-of-its-kind method to rapidly produce synchronized, human brain wave-like activity in lab-grown neural networks that can communicate over long distances. 

A new analysis shows that anti-inflammatory medications may help reduce symptoms for a subset of people with depression who also have chronic, low-grade inflammation. By reviewing randomized controlled trials that specifically enrolled individuals with elevated inflammatory markers, researchers found that anti-inflammatory treatments significantly reduced both overall depressive symptoms and anhedonia.

An international study has found that wearable technology could help detect Parkinson’s disease (PD) up to nine years before clinical diagnosis simply by monitoring how people turn when they walk.

Researchers have identified a distinct immuno-inflammatory biomarker across major psychiatric disorders that can be detected using noninvasive brain imaging. Patients exhibiting this brain signature showed systemic inflammation and poorer response to standard treatments.

A preliminary study of people with diabetes suggests that use of glucose-lowering GLP-1 drugs may be linked to a lower risk of developing epilepsy.

A new study proposes that autism arises when genetic vulnerability, an early environmental trigger, and prolonged activation of the cellular stress response align during critical developmental windows. This “three-hit” metabolic model reframes autism as a disorder of disrupted cellular communication and energy metabolism rather than an inevitable genetic outcome.

Finally this week, researchers have discovered how a neural circuit drives relapse after opioid use, a finding that could lead to more effective treatments for opioid use disorders.

Weekly Neuroscience Update

Mesoscale neural mechanisms of binocular rivalry in humans. Credit: Zhang Peng’s group

A research group has revealed how the human brain resolves perceptual conflicts and generates conscious perception through local inhibition in the sensory cortex and feedback integration from the parietal cortex.

A new clinical trial shows that deep brain stimulation (DBS) improved symptoms in half of adults with treatment-resistant depression, with one-third reaching remission.

A large-scale analysis of nearly 1,900 children found that those with a family history of substance use disorder show early differences in how their brains transition between activity states, long before any drug exposure. Girls with a family history showed increased transition energy in introspective networks, suggesting greater difficulty shifting out of internal, stress-linked states.

New research shows that spontaneous eye blinks naturally sync to the beat of music, revealing a hidden form of auditory-motor synchronisation that occurs even without conscious movement.

An extensive, two-year study of nearly 12,000 children found that higher screen time at ages 9–10 predicts an increase in ADHD symptoms, independent of a child’s starting symptom level. Brain imaging revealed that heavy screen use is associated with smaller cortical volume and disrupted development in regions critical for attention, cognition, and reward processing.

Researchers have identified five major phases of human brain wiring that unfold from birth to old age, marked by four major turning points at ages 9, 32, 66, and 83.

A new study shows that when two people work together toward a shared goal, their brains begin to process information in increasingly similar ways. Using EEG recordings, researchers found that while all participants showed similar early responses to visual patterns, only collaborating pairs developed sustained neural alignment linked to the rules they agreed upon.

A large analysis of more than 11 million medical records found that people with untreated obstructive sleep apnea face a substantially higher risk of developing Parkinson’s disease over time.

New research has revealed that Parkinson’s disease causes significant and progressive changes to blood vessels in the brain, changing our understanding of the disease which may lead to new treatment methods.

Diesel exhaust particles disrupt the function of the brain’s immune cells, a new study shows.

Researchers have developed a “virtual clinical trial” exploring a unique pharmacological treatment in patients who do not fully regain consciousness after a coma. The proposed treatment involves employing psychedelic drugs, such as psilocybin and lysergic acid diethylamide (LSD) that have intense, consciousness-altering effects in healthy volunteers.

A new meta-analysis shows that lithium supplementation does not significantly slow cognitive decline in people with mild cognitive impairment or Alzheimer’s disease.

New research shows that young adults with obesity already display biological patterns associated with liver stress, chronic inflammation, and early neural injury—changes typically seen in older adults with cognitive impairment. Participants with obesity also had unusually low blood choline levels, a nutrient critical for liver function, inflammation control, and long-term brain health.

A new study demonstrates that an AI assistant can conduct psychiatric assessment interviews with greater diagnostic accuracy than widely used mental health rating scales.

New brain imaging research shows that structural damage in schizophrenia spectrum disorders may begin in specific “epicenter” regions before spreading across connected brain networks. Individuals with the condition showed widespread reductions in structural similarity between key cognitive and emotional brain regions.

Finally, this week, researchers are exploring whether a person’s genetic risk for depression can help predict how multiple sclerosis (MS) progresses.

Weekly Neuroscience Update

Scientists have highlighted the most effective treatments for neurological diseases by overcoming one of medicine’s most difficult challenges: the blood–brain barrier. The findings offer new hope for patients with conditions including Alzheimer’s, and Parkinson’s disease, brain tumors, and epilepsy.

A study conducted in Finland showed that changes in the functioning of opioid neurotransmitters in the brain may underlie anorexia.

Poorer cardiovascular health in childhood and adolescence may be linked to early differences in brain structure, particularly in areas of the brain known to be affected in dementia in later life, according to a new scientific study.

Researchers have uncovered how specific patterns in brain activity can predict an individual’s sensitivity to pain, expanding opportunities for improved pain management strategies.

Delayed rapid eye movement (REM) sleep may be an early indicator of Alzheimer’s disease. Researchers found that participants with delayed REM sleep had higher levels of toxic proteins associated with Alzheimer’s and reduced levels of brain-derived neurotrophic factor (BDNF), which supports memory.

The microbial ecosystems in our mouths may impact cognitive function as we age, with pathogenic bacteria linked to cognitive decline.

New research suggests that mood swings in bipolar disorder are regulated by two clocks: the body’s 24-hour circadian rhythm and a dopamine-based clock that influences alertness. When these clocks align at specific intervals, they may trigger shifts between mania and depression.

A study in the Journal of Neuroscience reveals a new mechanism for how brain cells transmit signals from their tips to their nucleus, triggering gene activation crucial for learning and memory.

Investigators have discovered that activity in two widely distributed brain networks previously considered separate are actually correlated with each other and together play a key role in recognition memory, according to a study published in Cell Reports.

Cannabinoids offer new hope for safe and effective pain relief.

Researchers analyzed the genetic connection of retinal cells and several neuropsychiatric disorders. By combining different datasets, they found that schizophrenia risk genes were associated with specific neurons in the retina. The involved risk genes suggest an impairment of synapse biology, so the ability of neurons to communicate with each other. This impairment might also be present in the brains of schizophrenia patients.

Researchers at the University of Barcelona have identified a deficit in contrast perception in people with schizophrenia.

A study of nearly 1,000 people with post-COVID-19 syndrome (PCS) revealed that two-thirds still experienced significant symptoms, including reduced exercise capacity and cognitive performance, two years after infection. Persistent symptom clusters included fatigue, neurocognitive disturbances, and post-exertional malaise, with worse outcomes in individuals with obesity, lower education, or severe initial infections.

Finally this week, new research shows diets high in processed meat, fast food, and sugary drinks accelerate biological aging, even in young adults.

Weekly Neuroscience Update

Cortical gray matter volume trajectories based on the functional location of the changes in gestational mothers (N = 179). Credit: Nature Communications (2025).

A new study has analyzed the brains of women during pregnancy for the first time using neuroimaging techniques. The research shows that there is a reduction and partial recovery of almost 5% of gray matter in 94% of the total gray matter volume of the brain, especially in regions linked to social cognition.

An international team has shown the relationship of activity of neurotransmitters to how humans process the emotional content of language.

More than half of 23-year-olds in a European study show restrictive, emotional or uncontrolled eating behaviours, according to new research led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London. Structural brain differences appear to play a role in the development of these eating habits.

A new framework links brainwaves to individual cognitive states.

In a recent study, scientists have shown neurotransmitters in the human brain are active during the processing of the emotional content of language, providing new understanding into how people interpret the significance of words.

A new study shows stem cell therapy ‘jump-start’ brain repair after stroke.

Researchers have developed a flexible, biodegradable electrode capable of stimulating neural precursor cells in the brain, offering a safer and more precise alternative for neural repair. The electrode dissolves naturally after seven days, eliminating the need for surgical removal while promoting tissue regeneration.

Music supports babies in neonatal intensive care units, according to a recent neuroimaging study.

A study analyzing data from over 130 million individuals found that antibiotics, antivirals, vaccines, and anti-inflammatory medications are associated with a reduced risk of dementia. This supports the idea that infections and inflammation contribute to dementia and highlights the potential of repurposing existing drugs for prevention or treatment.

New research has uncovered psychological profiles associated with mental and brain health in middle-aged and older adults.

An experimental treatment for depression that triggers seizures with magnets significantly improved mental health in patients without some cognitive effects associated with electroconvulsive therapy (ECT), according to a clinical trial led by UT Southwestern Medical Center.

A research team has gathered new insight into the neural underpinnings of human cooperation.

A new study has identified three psychological profiles that influence brain health, cognitive decline, and dementia risk in aging adults. Profiles with high protective traits, like purpose and openness, show better cognition and brain integrity, while those with low protective traits or high negative traits face accelerated brain atrophy and mental health issues.

Stanford Medicine scientists are generating a periodic table of sorts for psychiatric disorders, providing a better understanding of these conditions and paving the way toward targeted treatment.

A study analyzing data from over 2 million veterans found that GLP-1 receptor agonists, popular weight-loss drugs like Ozempic and Wegovy, provide significant neurological and behavioral health benefits, including reduced risks of addiction, Alzheimer’s, and dementia. However, they also pose risks for pancreatitis and kidney conditions.

Finally, this week, a brain signal that lights up when we anticipate rewards may hold the secret to helping people overcome depression, and researchers are working to unlock its potential.

Weekly Neuroscience Update

A new study has shown neurotransmitters in the human brain are released during the processing of the emotional content of language, providing new insights into how people interpret the significance of words.

Researchers have identified how cerebrovascular disease disrupts brain connectivity, contributing to cognitive decline and neurodegeneration alongside Alzheimer’s disease. 

There may be a link between hearing impairment and an increased risk of developing Parkinson’s according to research led by Lancaster University.  Researchers analyzed data from over 159,000 individuals, finding that every 10-decibel increase in hearing loss corresponded to a 57% higher risk of Parkinson’s. While the findings highlight a strong association, the causality between hearing loss and Parkinson’s remains unclear.

A new systematic literature search has identified the highest priority clinical actions aimed at improving post-acute care for non-hospitalized traumatic brain injury.

Researchers are making strides in restoring touch sensations to prosthetic limbs through brain stimulation. By using electrodes in the brain’s touch center, they can evoke stable, precise sensations, even allowing users to feel the shape and motion of objects.

Increasing physical fitness levels has a causal link with better language comprehension, according to the first study to show this effect.

New research reveals that certain cells inactivate one parent’s copy of a gene, leading to a bias in gene activity that may explain why some individuals with disease-causing mutations remain symptom-free. This selective gene inactivation, known as monoallelic expression, affects about 1 in 20 genes and varies between cell types.

A new study from Karolinska Institutet and Mayo Clinic has revealed important insights into brain degeneration in dementia with Lewy bodies.

Tourette syndrome is currently diagnosed about three times more frequently in males than in females. A new study finds that females are less likely to be diagnosed with the syndrome, take longer to receive a diagnosis and are older when they are diagnosed than male individuals.

Finally this week, a new study has found that eating greater quantities of red meat, especially in processed forms, increases the risk for dementia.

Weekly Neuroscience Update

The four sensory networks of the brain network partition. The partition comprises four sensory networks, with the somatomotor network encompassing the somatosensory cortex. The thalamus contains parcels of each sensory network. Credit: Molecular Psychiatry (2024).

Researchers have uncovered a potential new biomarker for psychosis diagnosis.

A new approach to analyzing brain scans could help researchers better understand psychiatric illness using much smaller groups of patients than previously thought necessary, potentially accelerating the development of more precise mental health treatments.

A new study reveals how specific brain cells called interneurons can act as our in-built traffic controllers. The findings are published in the journal PLOS Biology.

Younger and middle-aged patients seem to be disproportionately affected by neurologic manifestations of post-acute sequelae of severe acute respiratory syndrome coronavirus 2 infection (Neuro-PASC), according to a study published in the Annals of Neurology.

Investigators have defined new biologic and clinical biomarkers for better identifying patients with different stages of Parkinson’s disease and Lewy body dementia.

Researchers have developed the most detailed 3D computational models of key brain regions, including the hippocampus and sensory cortices, to better understand their roles in memory formation and connectivity.

Healing the gut may be the key to improving long-term recovery in stroke patients, scientists at Texas A&M University have found.

New research provides critical insights into the role of sleep in motor learning for individuals recovering from traumatic brain injury (TBI). The study sheds light on how sleep, specifically a short nap, influences brain activity associated with motor skill improvement, with implications for optimizing rehabilitation strategies.

A recent study of high school football players found that concussions affect an often-overlooked but important brain signal.

Researchers have uncovered that stress changes how our brain encodes and retrieves aversive memories, and discovered a promising new way to restore appropriate memory specificity in people with post-traumatic stress disorder (PTSD).

Cognitive neuroscientists at Trinity College Dublin have published new research describing a brand new approach to making habit change achievable and lasting.

A new study uncovers constant communication between the human brain’s social cognitive network, responsible for understanding others’ thoughts, and the amygdala, known for processing fear and emotions. High-resolution brain scans revealed that this connection helps the brain integrate emotional importance into social interactions. This insight could lead to non-invasive treatments like transcranial magnetic stimulation (TMS) for anxiety and depression by targeting these regions. The findings highlight how evolutionary brain expansion enhances social understanding while linking it to ancient emotional processing centers.

Neuroscientists have demonstrated that dopamine and serotonin work in opposition to shape learning.

Researchers have identified a novel role for the brain’s ‘locus coeruleus’ in sleep and its disruptions. This brain region facilitates the transition between NREM and REM sleep states while maintaining an unconscious vigilance toward the external world. Stress disrupts its functions and negatively impacts on sleep quality.

A future treatment for Alzheimer disease may involve a nasal spray. 

A new method to profile gene activity in the living human brain has been developed by researchers at FutureNeuro, the Research Ireland Center for Translational Brain Science and RCSI University of Medicine and Health Sciences, in collaboration with international partners. This innovative approach, published in JCI Insight, opens new avenues for understanding and treating neurological conditions such as epilepsy.

A study led by the University of Glasgow has revealed differences in the brains of pediatric and adult patients that might explain the sometimes catastrophic outcomes seen in children following a traumatic brain injury.

Finally this week, new research has examined the relationship of emotion regulation to real-world responses to stress to better understand stress-related increases in suicide risk in depression.

Weekly Neuroscience Update

Large-scale functional networks are embedded along two principal gradients. Credit: Nature Neuroscience (2024).

Scientists have uncovered how different types of brain cells work together to form large-scale functional networks in the human brain—interconnected systems that support everything from sensory processing to complex decision-making—paving the way for new insights into brain health and disease.

A new neuroimaging marker of cerebral small vessel disease is related to general cognition and may serve to identify persons at risk of dementia in future clinical trials, a landmark study has found.

A recent study reveals that the genetic mutation causing Huntington’s disease (HD) enhances brain development and intelligence in early life, but leads to degeneration in adulthood. Children with the HD gene exhibit larger brains and higher IQs than those without the mutation.

In what could one day become a new treatment for epilepsy, researchers have used pulses of light to prevent seizure-like activity in neurons.

A team of researchers has found that certain factors are linked to faster brain shrinkage and quicker progression from normal thinking abilities to mild cognitive impairment (MCI). People with type 2 diabetes and low levels of specific proteins in their cerebrospinal fluid showed more rapid brain changes and developed MCI sooner than others.

A new study explores how brain waves reflect melody predictions while listening to music.

Neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, alleviates symptoms of major depression in as little as a few hours with effects lasting for several days.

New research indicates that cannabis use causes cellular damage that increases the risk of highly cancerous tumors by disrupting mitochondria and damaging DNA. 

Fampridine, used for improving walking in multiple sclerosis, may also enhance working memory in individuals with schizophrenia or depression. A study found that the drug significantly improved working memory in participants with initially poor performance, but had no effect on those with strong baseline memory.

A recent study links satellite and brain imaging data to identify how environmental factors can impact mental health, cognition and brain development in young people.

A new Alzheimer’s test collects just a few drops of blood from a finger prick, which can be mailed to a lab for analysis. The test measures biomarkers like pTau217 and has shown similar accuracy to traditional venous blood sampling.

Children born to mothers who take antiseizure medications during pregnancy may face increased risks of neurodevelopmental conditions, according to new data.

Researchers have shed light on the puzzling relationship between dopamine and rest tremor in Parkinson’s disease, finding that preserved dopamine in certain brain regions may actually contribute to tremor symptoms, challenging common beliefs.

New research has revealed the diverse assembly and regulation of Type-A GABA receptors (GABAARs), which are crucial for balancing brain activity. 

A recent study has found fascinating similarities in how the human brain and artificial intelligence models process language. The research, published in Nature Communications, suggests that the brain, like AI systems such as GPT-2, may use a continuous, context-sensitive embedding space to derive meaning from language, a breakthrough that could reshape our understanding of neural language processing.

A team of researchers has investigated the composition and communication of cells in so-called subcortical lesions, tissue damage to deep brain structures at different stages of multiple sclerosis.

Care for stroke survivors urgently needs to focus on non-motor skill outcomes such as fatigue, anxiety and reduced social participation to improve survivors’ quality of life and minimize care needs, according to a new study.

An international research collaboration has discovered how unusual spherical structures form in the brains of people with a mutation that causes a form of inherited Alzheimer’s disease. 

A new study identifies previously hidden brain network patterns in schizophrenia by focusing on nonlinear connectivity, offering potential biomarkers for early diagnosis. Traditional imaging methods often overlook these patterns, but researchers developed advanced statistical tools to uncover this new dimension of brain organization.

Finally this week, research published in the Journal of the American Geriatrics Society has identified several community-level factors that may increase people’s risk of experiencing cognitive impairment.

Weekly Neuroscience Update

Credit: The Journal of Physiology (2024). 

The team that first recorded vagus nerve signals in humans has now isolated the electrical activity of individual neurons responsible for cardiovascular regulation. Published in the Journal of Physiology, the Monash University-led discovery paves the way for more research into how and why cardiovascular disease develops.

New research reveals that dopamine is not directly responsible for the formation of placebo analgesia, contrary to previous beliefs.

Scientists have developed a new brain-mapping tool called START, which combines transcriptomics and viral tracing to map the connections between specific neuronal subtypes with unprecedented detail. This technology allows researchers to identify distinct patterns of connectivity in inhibitory neurons within the cerebral cortex, providing a blueprint of the brain’s circuits.

A new study has demonstrated that emotion enhances memory for contextual details, challenging the view that emotion impairs the ability to remember such information.

Researchers compared the diagnostic accuracy of GPT-4 based ChatGPT and radiologists using 150 brain tumor MRI reports. ChatGPT achieved 73% accuracy, slightly outperforming neuroradiologists (72%) and general radiologists (68%).

Deep brain stimulation may provide immediate improvement in arm and hand strength and function weakened by traumatic brain injury or stroke.

People with Parkinson’s disease (PD) who experience visual hallucinations have reduced brain responses to unexpected visual changes, a marker known as visual mismatch negativity (vMMN). Using EEG, researchers compared brain activity in PD patients with and without hallucinations and discovered that those with hallucinations showed weaker vMMN signals

Lower attention ability in adolescence can predict cigarette and cannabis use in young adulthood, according to new research from Trinity College Dublin.

New research has found that frequent consumption of fizzy drinks and fruit juice significantly increases the risk of stroke. The study, which analyzed data from nearly 27,000 participants across 27 countries, showed a 22% increased risk of stroke from drinking fizzy drinks, with the risk rising further with multiple servings per day. Additionally, drinking more than four cups of coffee daily raised stroke risk by 37%, while tea consumption was associated with a reduced stroke risk. 

New research shows that even pollution levels that are below government air-quality standards are associated with differences in children’s brains.

University of Queensland researchers have made a significant step towards enabling women with epilepsy safer access to a common and highly effective anti-seizure medication.

A new study shows that brain synchronization between a neurotypical person and someone with autism is weaker compared to two neurotypical individuals interacting. Using EEG hyperscanning, researchers observed reduced inter-brain synchrony during hand movement imitation between mixed pairs, with autistic individuals more likely to follow than lead.

Certain immune cells play an important role in the early stages of multiple sclerosis, a twin study shows.

New evidence from the Centre for Healthy Brain Ageing indicates that older adults who experience a stroke for the first time will have substantial immediate and accelerated long term-cognitive decline. The new research, published iJAMA Network Open, looked at finding out exactly how a stroke impacts a person’s cognitive abilities.

A new study shows how individual brain cells in the hippocampus respond to pronouns.

Scientists are examining the brains of individuals with asymptomatic Alzheimer’s disease who, despite having amyloid plaque and tau buildup—the primary indicators of Alzheimer’s—did not show diagnosable dementia symptoms while alive. They’ve identified crucial mechanisms that may safeguard against cognitive decline in Alzheimer’s disease.

Finally this week, In a first-of-its-kind study, University of South Florida researchers are finding that music can help boost cognition in patients undergoing chemotherapy. 

Weekly Neuroscience Update

Pupillary light reflex (PLR) assessment in open-eye and closed-eye conditions. Credit: Communications Medicine (2024).

A new technological advancement now enables researchers to observe changes in pupil size and gaze direction behind closed eyelids for the first time, using non-contact infrared imaging. This capability is expected to aid in identifying wakefulness states during sleep, anesthesia, and intensive care by monitoring pupil size variations. It could also be instrumental in gauging sedation levels, detecting seizures and nightmares, and acknowledging pain or responsiveness following trauma or within intensive care settings.

Neuroscientists have uncovered serotonin’s role in resilience.

A recent study using artificial intelligence has yielded a new understanding of how the brain anticipates future occurrences and processes data. It was found that the brain’s inherent activity, even in the absence of external stimuli, is crucial to our cognitive and emotional processes.

New research shows that varied cognitive training, rather than repetitive tasks, helps older adults improve working memory.

Scientists have mapped how propofol, a widely used anesthetic, alters brain connectivity to induce unconsciousness. Using fMRI, they found that propofol disrupts connections in the thalamus, reducing complex information processing and limiting sensory integration.

Research on older individuals indicates that vision impairment may be responsible for one in five dementia cases.

A new technology that uses harmless light waves to measure activity in babies’ brains has provided the most complete picture to date of brain functions like hearing, vision and cognitive processing outside a conventional, restrictive brain scanner.

Heat waves can worsen abnormal excitability of the brain in people with epilepsy, finds a new small-scale patient study.

Scientists have developed an innovative approach to studying brain connections using functional magnetic resonance imaging (fMRI). Recently published in Cell Systemsthis work introduces a new way of understanding brain architecture through dynamic functional networks, challenging the traditional static approach.

New research identifies potential therapeutic target for amyotrophic lateral sclerosis (ALS).

A new study published in Nature Communications examines how the brain initiates spontaneous actions. In addition to demonstrating how spontaneous action emerges without environmental input, this research has implications for the origins of slow ramping of neural activity before movement onset—a commonly-observed but poorly understood phenomenon.

Researchers have published a novel study exploring the effects of delayed feedback on learning in individuals with moderate-to-severe traumatic brain injury (TBI).

A breakthrough in medical imaging is making it possible for researchers to observe brain activity during movement and pick up the early signs of disorders that affect brain-to-body coordination, such as Parkinson’s disease.

A new study investigated the origin of ataxia in the brain of patients with stroke and found a significant number of the stroke lesions in the patients were located outside the cerebellum.

Researchers have developed a noninvasive technique that could dramatically improve the way doctors monitor intracranial hypertension, a condition where increased pressure in the brain can lead to severe outcomes like strokes and hemorrhages.

Robotic ‘coaches’ aiding upper limb rehabilitation for stroke and brain injury survivors have been successfully trialed in Vienna, Austria.

Scientists have created a dynamic technique to monitor swift changes in brain activity, particularly those associated with cravings. This method differs from conventional neuroimaging by offering a continuous perspective on the variations in craving intensity. The research revealed that individuals with intense cravings tend to remain longer in brain states that intensify these cravings and do not activate the brain networks that could diminish them.

A recent study highlights the interaction between brain structure and social context, suggesting that some children are more vulnerable to social stressors than others.

With maps of the connections between neurons and artificial intelligence methods, researchers can now do what they never thought possible: predict the activity of individual neurons without making a single measurement in a living brain.

A review highlighting recent advances in genetically encoded fluorescent tools for labeling and selectively manipulating synapses has been published in Nature Reviews Neuroscience.

Researchers have investigated the correlations between outdoor nighttime light pollution and Alzheimer’s disease, finding that excessive light pollution may elevate the risk of Alzheimer’s, particularly in younger individuals.

Finally this week, brain waves can be manipulated while in rapid eye movement (REM) sleep, a sleep stage associated with memory and cognition, a new study from the University of Surrey finds. 

Weekly Neuroscience Update

Credit: Frontiers in Human Neuroscience (2024)

Scientists have determined that more than 60% of people who contracted COVID-19 have neurological symptoms that impact their cognitive function and quality of life, even two and three years after COVID-19.

Lip-read words can be decoded from the brain’s auditory regions similarly to heard speech, according to a new report that looked at how vision supports verbal perception.

Exercising is healthy, but not always appealing. Now research may have found a “switch” that activates the desire to get moving, as it shows that during exercise the muscle activates proteins which encourage further activity. The paper is published in Science Advances.

Researchers have demonstrated that a simple blood test that reflects brain health can predict which people are most at risk of suffering a stroke.

Our brain interprets visual information by combining what we see with what we already know. A study published in the journal Neuron, reveals a mechanism for learning and storing this existing knowledge about the world.

A newly developed brain-computer interface translates brain signals into speech with up to 97% accuracy, making it the most precise system of its kind.

Researchers have discovered that spontaneous brain activity during early development drives neural wiring before sensory experiences shape the brain. This spontaneous activity in neurons strengthens connections, following Hebb’s rule, where “cells that fire together wire together.”

According to new research, cognitive impairments in psychotic disorders, such as schizophrenia and bipolar disorder, are linked to brain network organization. 

A recently published study has unveiled significant findings that could enhance brain-computer interface (BCI) technologies, marking a crucial step towards more intuitive neuroprosthetic control and advanced rehabilitation therapies.

Researchers have discovered that the hippocampus stores multiple copies of a single memory, each within different neuron groups that develop at different stages.

Scientists have developed a promising preventative therapeutic approach against Alzheimer’s disease, targeting the amyloid beta biomolecule that typically triggers nerve cell hyperactivity in the early stages of the brain disease.

A new study finds that COVID-19 proteins left in the brain may lower cortisol levels, leading to heightened inflammation and an exaggerated response to stressors.

Through a large-scale brain imaging study, an international research team has identified five patterns of age-related degeneration in older people experiencing mental decline. In their study, the team conducted the multi-year study of thousands of MRI scans using machine learning applications to find patterns in brain degeneration as people age.

A new machine learning model, AutMedAI, can predict autism in children under two with nearly 80% accuracy, offering a promising tool for early detection and intervention.

Researchers have discovered the neurons responsible for “item memory,” deepening our understanding of how the brain stores and retrieves the details of “what” happened and offering a new target for treating Alzheimer’s disease.

Contrary to previous research, a new study of female participants finds no link between migraine and the risk of developing Parkinson’s disease.

Children who have persistently raised inflammation are at a higher risk of experiencing serious mental health disorders including psychosis and depression in early adulthood, according to a study published today in JAMA Psychiatry.

Researchers have identified a link between brain overgrowth and the severity of social and communication symptoms in children with autism spectrum disorder. 

People with multiple sclerosis (MS) are far less likely than those without the condition to have the molecular hallmarks of Alzheimer’s disease, according to new research. The discovery suggests a new avenue of research through which to seek Alzheimer’s treatment.

Scientists have discovered a new method to regulate the receptors responsible for the sense of touch, potentially leading to more effective treatments for chronic pain.

Researchers have found that nondeceptive placebos—placebos given with the full knowledge that they are placebos—can effectively manage stress, even when administered remotely. In a two-week randomized controlled trial, participants experiencing prolonged stress were divided into two groups: one group received nondeceptive placebos, while the other served as a control.

Return to work two years after a breast cancer diagnosis is associated with higher cognitive speed performance before and after treatment, according to a study published in JAMA Network Open.

Researchers have discovered a mutation in the SARS-CoV-2 spike protein that enhances its ability to infect the central nervous system, potentially explaining neurological symptoms and long COVID. The mutation was found to allow the virus to better infiltrate the brain, with implications for future treatments targeting COVID-19’s effects on the brain. 

Finally, this week, while everyone knows that a good night’s sleep restores energy, a new study finds it resets another vital function: memory.