*Mapping network connectivity to cycles of seizure likelihood. Credit: Nature Medicine (2024)*

A team of epilepsy specialists has developed a method to forecast the risk of a seizure within 24 hours. The researchers demonstrated that the surge of brain activity indicative of a seizure is preceded by unusual communication among certain brain regions. By examining a mere 90 seconds of these atypical brain signals, the researchers were able to predict the likelihood of a seizure.

A significant discovery by Australian scientists has the potential to improve the effectiveness of drugs currently used to manage cognitive decline in patients with Alzheimer’s disease.

A new study reveals that quick learners of motor skills have distinct brain activity patterns. Using brain-monitoring electrodes, they found that visual processing plays a crucial role in learning new movements. Fast learners showed higher activity in brain regions linked to visual information and muscle movement planning. These findings highlight the importance of vision in acquiring motor skills and its implications for older adults.

Exercising our brains with daily habits like naps and memory workouts, instead of relying on smartphones, can reduce the risk of age-related dementia.

Star-shaped glial cells, so-called astrocytes, are more than just a supporting cell of the brain. They are actively involved in learning processes and interact with nerve cells. Now scientists are using a biophysical model to clarify how astrocytes interact with nerve cells to regulate rapid adaptation to new information. The results of the study have now been published in Communications Biology.

New research shows that inflammation outside the brain, such as that caused by common infections such as colds and urine infections, is linked to the progression of multiple sclerosis (MS).

Recent advances in the study of proteomes (i.e., the entire range of proteins expressed by human cells and tissues) have opened new opportunities for identifying the biological markers of specific diseases or mental disorders. This could in turn inform the prevention, diagnosis and treatment of these medical conditions.

A new experimental cancer drug could ease cognitive difficulties for those with Rett syndrome, a rare autism-linked disorder, by enhancing brain cell functions.

An MIT study published in Nature provides new evidence for how specific cells and circuits become vulnerable in Alzheimer’s disease, and hones in on other factors that may help some people show resilience to cognitive decline, even amid clear signs of disease pathology.

Neuroscientists have discovered the brain circuitry of placebo effect for pain relief.

A new study demonstrates how the external representation of physiological signals (interoception) can affect our perception of them and teach us how to improve them in order to balance the body in stressful situations, for example. The study was recently published in the journal Scientific Reports.

An interdisciplinary team of scientists has found differences between male and female brain structure in areas associated with decision-making, memory processing and handling emotions.

A new study proposes a novel approach to studying consciousness through behavioural observations and learning curves, highlighting that learning often occurs in sudden leaps, suggesting these “eureka moments” are preceded by conscious cognitive processes.

Finally this week, there is a potential connection between a diagnosis of certain gastrointestinal (GI) syndromes and the formation and rupture of intracranial (brain) aneurysms according to new research.

Weekly Neuroscience Update

May 17, 2024May 17, 2024Leave a comment

Researchers at University of Cambridge and other institutes worldwide recently carried out a study that linked gene expression in healthy brains to the imaging, transcriptomics and genetics of autism spectrum disorder and schizophrenia. Their paper, published in Nature Neuroscience, unveiled three distinct spatial patterns of cortical gene expression each with specific associations to autism and schizophrenia

A study published in the Journal of the American College of Cardiology suggests that physical activity may reduce cardiovascular disease risk by lowering stress-related brain activity.

A team of researchers at Baylor College of Medicine and Yale University incorporated generative artificial intelligence (AI) to create a foundational model for brain activity. The Brain Language Model (BrainLM) was developed to model the brain in silico and to determine how brain activities are related to human behavior and brain diseases.

Using MRI, engineers have found a way to detect light deep in the brain.

Stressful life events, such as the death of a loved one or divorce, put a person at greater risk of developing dementia in later life, a recent study has found. But only if the stressful event happened in childhood or midlife.

Our brains process odours differently depending on the names assigned to them, according to new research.

People with neurological disease have a greater chance of death after contracting COVID-19, according to a new study. The research also confirms a higher risk of developing new neurological disorders after COVID infection.

Children who experience chronic lack of sleep from infancy may be at increased risk of developing psychosis in early adulthood, new research shows.

A team of brain specialists at the California Institute of Technology has developed a brain–computer interface approach to decode words “spoken” entirely in the brain by recording signals from individual neurons in real time.

A new study shows that the cerebellum is involved in processing emotions, with implications for ataxia care.

A research team has revealed the link between the frequency of sleep apnea events during the rapid-eye-movement stage and the severity of verbal memory impairment in older adults at risk for Alzheimer’s disease. Verbal memory refers to the cognitive ability to retain and recall information presented through spoken words or written text and is particularly vulnerable to Alzheimer’s.

Results from a recent neuroplasticity study show how singing rehabilitates speech production in post-stroke aphasia.

For the first time, researchers have succeeded in explaining the propagation of traveling waves of activity in the human brain using a computer simulation. Previous studies indicate that these waves are important for various cognitive functions such as memory.

A new publication in Scientific Reports unveils a promising non-opioid pain treatment.

Repeated blows to the heads of football players can damage the small blood vessels of the brain, according to research by scientists who believe this damage may contribute to brain dysfunction in some athletes years after play has ended.

New research has shed light in the complex interplay between cell proteins, and how they impact on neurons in neurodevelopmental disorders and Alzheimer’s disease.

Artificial intelligence (AI) computer programs that process MRI results show differences in how the brains of men and women are organized at a cellular level, a new study shows. These variations were spotted in white matter, tissue primarily located in the human brain’s innermost layer, which fosters communication between regions.

Finally, this week, climate change, and its effects on weather patterns and adverse weather events is likely to negatively affect the health of people with brain conditions.

Pain and Your Brain

July 13, 2020July 14, 2020Leave a comment

Why do people experience the same pain differently, and why can the same pain seem worse to a single individual from one day to the next?

Find out the answers in this recent online presentation for the Migraine Association of Ireland.

Weekly Neuroscience Update

September 13, 2019Leave a comment

A team of neuroscientists from Göttingen and Tehran has shown. how our brain combines visual features to achieve a unified percept.

Research published in the journal Cerebral Cortex has shown that stronger functional connectivity—that is, communication among neurons in various networks of the brain—is linked to youthful memory in older adults. Those with superior memories—called superagers—have the strongest connectivity.

Scientists have found a link between brain’s emotion circuit and movement.

High-fat diets are not only bad for your waistline, they are also bad for your brain health. A new study reveals high-fat diets contribute to hypothalamic inflammation which occurs long before symptoms of obesity arise.

Patients with schizophrenia show increased brain activity in central areas of the brain, but lower activity in the temporal sulcus when hearing metaphors.

Researchers have developed a system that measures a patient’s pain level by analyzing brain activity from a portable neuroimaging device. The system could help doctors diagnose and treat pain in unconscious and noncommunicative patients, which could reduce the risk of chronic pain that can occur after surgery.

Finally this week, a new study reports maternal marijuana use may be detrimental to the brain development of children.

Weekly Neuroscience Update

December 10, 2016December 10, 2016Leave a comment

It may be possible to categorise the brain strategies used by professional musicians based on how they prioritise sight vs. sound when learning to play new music, according to a new study.

When we are in a deep sleep our brain’s activity ebbs and flows in big, obvious waves, like watching a tide of human bodies rise up and sit down around a sports stadium. It’s hard to miss. Now, Stanford researchers have found, those same cycles exist in wake as in sleep, but with only small sections sitting and standing in unison rather than the entire stadium. It’s as if tiny portions of the brain are independently falling asleep and waking back up all the time.

Researchers report the hippocampus isn’t just important for remembering past events, it also plays a vital role in future planning.

According to a new study, the brain blocks the ability for creating new memories shortly after waking in order to prevent the disruption of the stabilisation of memory consolidation that occurs during sleep.

Patients with depression can be categorised into four unique sub-types defined by distinct patterns of abnormal connectivity in the brain, according to new research.

The inability to hear subtle changes in pitch, a common and debilitating problem for people with schizophrenia, is due to dysfunctional N-methyl-D-aspartate (NMDA) brain receptors, according to a study by Columbia University Medical Center (CUMC) researchers. The study also shows that this hearing issue can be improved by combining auditory training exercises with a drug that targets NMDA receptors.

Researchers report abnormal activation in areas that respond to normal pain when a person with CRPS witnesses another person experience painful stimuli.

A new study has revealed the way that the brain handles the often noisy environments found on this planet, with the results explaining why animals, including humans, can easily cope with both the still and quiet of early-morning parks to the bustle and hubbub of cafés and streets. The researchers discovered that as auditory neurons become more familiar with a sound environment, they speed up their adaption to the noisiness of that environment.

The human brain is predisposed to learn negative stereotypes, according to research that offers clues as to how prejudice emerges and spreads through society.

Finally this week, researchers have conducted the first study of its kind, using proton magnetic resonance spectroscopy (MRS) to look at brain regions in both adults and children who stutter.

Pain and the Brain (Video)

November 13, 2016Leave a comment

Sean Mackey, MD, PhD, Redlich Professor and Chief of the Division of Pain Medicine at Stanford University, speaks on “Pain and the Brain” at Stanford Back Pain Education Day 2016.

Weekly Neuroscience Update

October 29, 2016October 29, 2016Leave a comment

Heading a football can significantly affect a player’s brain function and memory for 24 hours, a study has found.

Researchers have successfully transplanted embryonic neurons into damaged neural networks, a new study reports.

Scientists have identified for the first time the region in the brain responsible for the “placebo effect” in pain relief.

Results from a new clinical study conducted suggest that curtailing sleep alters the abundance of bacterial gut species that have previously been linked to compromised human metabolic health.

A new imaging technique that creates 3-D video of serotonin transport could aid antidepressant development.

Researchers have identified the cause of chronic, and currently untreatable, pain in those with amputations and severe nerve damage, as well as a potential treatment which relies on engineering instead of drugs.

A new study could explain why the ‘one size fits all’ approach to treating depression has been ineffective.

Using optogenetics to activate dopamine receptors in the ventral tegmental area could help people regain consciousness following general anesthesia, researchers report.

We all know that as we age, our skin loses its firmness and elasticity. However, researchers have now discovered our brains may also lose its elasticity as we age.

Researchers have identified a common culprit that may cause damage in stoke, brain injury and neurodegenerative disease.

Finally this week, A new study provides the first empirical evidence that self-serving lies gradually escalate and reveals how this happens in our brains.

Weekly Neuroscience Update

February 9, 2014Leave a comment

The salience network, highlighted here in two epilepsy patients, is thought to mediate our response to important internal or external signals, such as pain or the sound of a siren. Image: Parvizi et al. Neuron 2013

In a rare study involving direct brain stimulation researchers say they have uncovered direct evidence that a brain region known as the anterior midcingulate cortex and its surrounding network play a central role in motivation and a readiness to act.

Many studies suggest that pushing your brain to multitask—writing emails, for instance, while watching the day’s latest news and eating breakfast—leads to poorer performance and lower productivity. But for at least one everyday task—visual sampling (the act of picking up bits of visual information through short glances)—multitasking is not a problem for the brain. A collaboration between researchers at the UC Santa Barbara and the University of Bristol in the UK has shown that during visual sampling, the brain can handle various visual functions simultaneously.

Researchers report a detailed account of how speech sounds are identified by the human brain, offering an unprecedented insight into the basis of human language. The finding, they said, may add to our understanding of language disorders, including dyslexia.

A new study correlating brain activity with how people make decisions suggests that when individuals engage in risky behavior, it’s probably not because their brains’ desire systems are too active, but because their self-control systems are not active enough. This might have implications for how health experts treat mental illness and addiction or how the legal system assesses a criminal’s likelihood of committing another crime.

Pain sensitivity is controlled by a genetic “dimmer switch”, which can be re-set, UK scientists have discovered.