Tag: neuroscience

Weekly Round Up

In a new study, participants who received electrical stimulation of the anterior temporal lobes were three times as likely to reach the fresh insight necessary to solve a difficult, unfamiliar problem than those in the control group. (Credit: iStockphoto/Andrey Volodin)

In this week’s round-up of the latest discoveries in the field of neuroscience – electric thinking caps, shrinking brains, brain controlled bionic arms, expanding memories..and much more.

Are we on the verge of being able to stimulate the brain to see the world anew with an electric thinking cap? Research by Richard Chi and Allan Snyder from the Centre for the Mind at the University of Sydney suggests that this could be the case.

Human brains have shrunk over the past 30,000 years, but it is not a sign of decreasing intelligence, according to scientists who suggest that evolution is making the key motor leaner and more efficient in an increasing population.

The LA Times reports that the FDA are about to test a brain-controlled prosthetic arm. The arm system, developed by the Defense Advanced Research Projects Agency, uses a microchip implanted in the brain to record and decode signals to neurons that control muscles linked to the prosthesis.

Interesting abstract in the New Scientist which shows that just as gardeners prune unwanted growths from flowers, the brain has its own molecular secateurs for trimming back unwanted connections.

Researchers have identified a protein that appears vital for forming the right kind of connections in the rapidly growing brain of newborn babies.

New research by scientists at Royal Holloway, University of London provides evidence that the cerebellum, a part of the brain used to store memories for skilled movements, could also store memories important for mental skills

Research conducted with deaf people in Nicaragua shows that language may play an important role in learning the meanings of numbers.

In the Neuroscience of Resilience, Lisa Brookes Kift is asking the question what does the brain and neuroscience have to do with building up our  resilience?

Finally, if you do just one thing this weekend, make it a walk. A report in the New York Times this week reveals that taking a walk may expand the hippocampus – a part of the brain important to the formation of memories. In healthy adults, the hippocampus begins to atrophy around 55 or 60. So get your walking shoes on this weekend!

Weekly Update

People’s brains are more responsive to friends than to strangers, even if the stranger has more in common, according to a study in the Oct. 13 issue of The Journal of Neuroscience.

In Time magazine’s What Your Brain Looks Like After 20 Years of Marriage, Belinda Luscomb has been taking a look at the neuroscience of love.

And speaking of love, new research has also found that falling in love only takes about a fifth of a second!

And what exactly is going on in your brain if you are looking back with nostalgia at past loves? I came across a fascinating article on the neuroscience of nostalgia and memories.

Now a question for you? How many of you feel you have lost the art of writing by hand, now that we are all so computer literate these days?  Associate professor Anne Mangen at the University of Stavanger’s Reading Centre asks if something is lost in switching from book to computer screen, and from pen to keyboard and discovers that writing by hand does indeed strengthen the learning process.

Weekly Round-Up

Do you gesture while you talk? These gestures seem to be important to how we think. They provide a visual clue to our thoughts and, a new theory suggests, may even change our thoughts by grounding them in action.

In  how the brain shops, we have an exploration of the neurons associated with valuing objects, and on a related theme,  A.K. Pradeep’s  Marketing to Women examines how women shop using their instinct.

An interesting study from Dehaene et al. on how reading rewires the brain 

Latest research shows that emotional stress can change brain function. A single exposure to acute stress affected information processing in the cerebellum — the area of the brain responsible for motor control and movement coordination and also involved in learning and memory formation.

Neuroscientists at MIT’s Picower Institute of Learning and Memory have uncovered why relatively minor details of an episode are sometimes inexplicably linked to long-term memories.

Finally, are you feeling a little bored? Well new research suggests that it is not just in your head. Individual differences in sensitivity to reward, for example, are another important factor.

The neuroscience of music

I am interested in ongoing research focusing on the effects of music training on the nervous system, and have given some talks on the subject over the past few years. It is also very interesting to note from recent studies that music training has implications for neuroeducation.

Research from Northwestern’s Auditory Neuroscience Laboratory strongly suggests that an active engagement with musical sounds not only enhances neuroplasticity, but also enables the nervous system to provide the stable scaffolding of meaningful patterns so important to learning.

According to Northwestern’s Professor Nina Kraus, director of  Northwestern’s Auditory Neuroscience Laboratory “The brain is unable to process all of the available sensory information from second to second, and thus must selectively enhance what is relevant,” Kraus said. Playing an instrument primes the brain to choose what is relevant in a complex process that may involve reading or remembering a score, timing issues and coordination with other musicians.”

Again, I am most interested to note that in Northwestern’s research shows that children who are musically trained have a better vocabulary and reading ability than children who did not receive music training.

Furthermore Professor Kraus says that “Music training seems to strengthen the same neural processes that often are deficient in individuals with developmental dyslexia or who have difficulty hearing speech in noise.”

Professor Kraus argues for proper investment of resources in music training in schools: “The effect of music training suggests that, akin to physical exercise and its impact on body fitness, music is a resource that tones the brain for auditory fitness and thus requires society to re-examine the role of music in shaping individual development. ”

“Music training for the development of auditory skills,” by Nina Kraus and Bharath Chandrasekaran, will be published July 20 in the journal Nature Reviews Neuroscience.

Weekly Round-Up

 

Eternal Sunshine Of the Spotless Mind

Would you take a pill to erase bad memories?

 

New Year is traditionally a time for many people to make a resolution to give up smoking. The smoking cessation medications bupropion and varenicline may both be associated with changes in the way the brain reacts to smoking cues, making it easier for patients to resist cravings, according to two reports posted online that will appear in the May print issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

If you are a parent of a teen going through puberty you will know all about the hormonal changes they go through.  Now, a Georgia State University scientist has found that those hormones in males may be key to changes in a part of the brain responsible for social behaviors.

It will take some time for those teen brains to develop fully though, as we know now from new research that the brain continues to develop after childhood and puberty, and is not fully developed until people are well into their 30s and 40s. The findings contradict current theories that the brain matures much earlier.

And still on the subject of teenagers, PBS science correspondent, Miles O’Brien looks at what could be happening to teenage brains as they develop in a rapid-fire world of technology and gadgets.

Finally, if you have ever watched the 2004 movie Eternal Sunshine of the Spotless Mind, you will have seen the fictional characters played by Jim Carrey and Kate Winslet use a technique to erase memories of each other when their relationship turns sour. It will have seemed an unreal expectation that we could erase memories so easily, but new research on “erasing” traumatic memories is quickly moving from the realm of science fiction to scientifically backed reality.

Introducing a new feature today – a weekly round-up of the best of the neuroscience news and views and latest research which has caught my attention.

How to use your brain to win friends and influence people

You are probably familiar with the  lyrics of James Taylor’s “You’ve got a friend” and indeed “ain’t it good to know you’ve got a friend when nothing’s going your way.”

But did you know that you have a friend you can call on who is with you all the time?

Say hello to your amydgala – your very own social satnav and your faithful friend.

So what is this amygdala and what role does it play in forming friendships and widening your social network?

Your amydgala 

Deep down in our reptilian brain lies a small thumbnail-sized structure with a name derived from the Greek word for almond. The amygdala has long been linked with a person’s mental and emotional state – in particular an emotional response – often an instant reaction – to something presently happening such as a perceived threat including the behaviours of escape and avoidance.

The bull who would not charge

As far back as the 1950’s a Spanish neuroscientist called Delgado used a tiny radio frequency stimulator implanted into the amygdala – the activation of which produced a variety of effects, including pleasant sensations. Delgado’s most famous experiment occurred at a Cordoba bull breeding ranch where he stepped into the ring with a bull which had a stimulator already implanted in the amygdala. The bull charged Delgado, who then pressed a remote control button which caused the bull to lose its aggressive instinct and to stop its charge. The bull incident was widely mentioned in the popular media at the time.

The amygdala alerts you to danger

In another important study – when brain images were recorded while persons were shown emotionally upsetting films, such as plane crashes or killer whales dismembering and eating baby seals and increase in the activity of the amygdala was observed suggesting that it is involved in storing memories for emotional events. Over the past 10 years neuroscientists have discovered that for it small size the amygdala is very complex with connections to and from many other brain regions and plays a protective role primarily involved in protection, moving us away from potentially dangerous situations.   

You’ve got a friend in your amygdala

In a social situation the amygdala processes reactions to violations concerning personal space. These reactions are absent in persons in whom the amygdala is damaged. Furthermore, the amygdala is found to be activated in when people observe that others are physically close to them, such as when a person being brain scanned knows that an experimenter is standing immediately next to the scanner, versus standing at a distance.

Behold the next big thing in social networking…the amygdala!

In interesting research published recently in the Journal, Nature Neuroscience  it has been shown that the size of your amygdala correlates with the size of your social network – taking the role of the amygdala in social interaction to another level. As a social species a larger amygdala gives us more options to manage our complex social lives – helping us to get along while getting ahead.

Thus jobs involving meeting people such as shopkeepers – who may interact with hundreds people including customers, suppliers and employes in an average day – will develop a larger and more intricately wired amygdala than say someone in solitary confinement.

All this points back to a fundamental finding in neuroscience – your brain is plastic.  So the message is simple – you need to meet as many people as possible if you want a rich and varied social life. You may not get along with everyone but as you learn and persist your amygdala will become your very own on-board social satnav.

 

Exercise doesn’t just make you fitter – it makes you smarter too!

Exercise is important in keeping your heart and lungs healthy. We know for decades that the effort required in exercise allows life-giving oxygen to travel quicker and in greater amounts to all the tissues of the body – allowing the cells in them to grow and divide. A noticeable exception to this rule is the brain.

Neurons are different

Nerve cells or neurons are notoriously bad at dividing. Rather than divide, a neuron survives by making up to 10,000 connections to neighbouring neurons – and this is the key to how we learn and recall as memories are created and strengthened.  This compromise works well for the first four decades of life however by your 50’s a gradual loss of neurons and their connections starts to take it toll resulting in a noticeable reduction in cognition as we find it harder to remember, especially recent events. 

An unexpected finding

Recent scientific findings from Columbia University show that exercise is important in helping to reverse this age-related loss of neurons. In this study in a small group of middle-aged people, exercising just an hour a day, four times a week, for three months triggers the growth of new neurons – a feat which has previously proved almost impossible for neuroscientists to achieve using drugs. Neuroscientists are still working out the possible reasons why simple exercise is so powerful at triggering the birth of neurons but a clue may be that the brain is very well supplied by blood vessels needed to deliver the food and oxygen to help make and maintain the trillions of synapses in the brain. In fact the brain is one of the most oxygen-sensitive organs of the body. It receives 20% of the cardiac output and accounts for about 25% of overall resting oxygen consumption. In addition, the brain as a highly vascular organ is very sensitive to changes in blood perfusion. It seems the extra increase in blood perfusion and life-giving oxygen associated with exercise may invigorate the brain to such a degree that it starts to actually grow new neurons again.

Exercise is as important as drugs

The finding that exercise triggers the brain to grow new nerve cells is a truly stunning discovery that will have implications for public healthcare policies for an increasingly ageing population. In addition, new treatments for brain illness such as Alzheimer’s disease and head injury may involve a combination of different therapies such as medication, psychological therapies, social support, self-help techniques and now, most importantly exercise. This combined approach will treat the person as a whole, and marks the beginning of the journey back to wellness and a normal life.

So the message is simple –if you want to stay smart just get out there and exercise.

How to increase serotonin in the brain without drugs

Aerobic exercise has been shown to elevate mood

As a follow-on to my last post on depression, I would like to direct you to an article I have stumbled upon from the Journal of Psychiatry and Neuroscience (1) published in 2007.

Its primary focus is on individuals with a serotonin-related susceptibility to depression, and nonpharmacologic methods of increasing serotonin to prevent depression in those with such a susceptibility.

Nonpharmacologic methods of raising brain serotonin may not only improve mood and social functioning of healthy people — a worthwhile objective even without additional considerations — but would also make it possible to test the idea that increases in brain serotonin may help protect against the onset of various mental and physical disorders.

The article discusses four possible strategies that are worth further investigation:

1. Altering Thought Patterns

The idea that alterations in thought, either self-induced or due to psychotherapy, can alter brain metabolism is not new. Numerous studies have demonstrated changes in blood flow in such circumstances. However, reports related to specific transmitters are much less common. In one recent study, meditation was reported to increase release of dopamine.The study by Perreau-Linck and colleagues (2) is the first to report that self-induced changes in mood can influence serotonin synthesis.

2. Exposure to Bright Light

Bright light is, of course, a standard treatment for seasonal depression, but a few studies also suggest that it is an effective treatment for nonseasonal depression and also reduces depressed mood in women with premenstrual dysphoric disorder and in pregnant women suffering from depression.

3. Exercise

A third strategy that may raise brain serotonin is exercise. A comprehensive review of the relation between exercise and mood concluded that antidepressant and anxiolytic effects have been clearly demonstrated.

4. Diet

According to some evidence, tryptophan, which increases brain serotonin  is an effective antidepressant in mild-to-moderate depression. Further, in healthy people with high trait irritability, it increases agreeableness, decreases quarrelsomeness and improves mood. However, the idea, common in popular culture, that a high-protein food such as turkey will raise brain tryptophan and serotonin is, unfortunately, false. Another popular myth that is widespread on the Internet is that bananas improve mood because of their serotonin content. Although it is true that bananas contain serotonin, it does not cross the blood–brain barrier.

To read this article in full please click here.

1. J Psychiatry Neurosci. 2007 November; 32(6): 394–399.

2. Perreau-Linck E, Beauregard M, Gravel P, et al. In vivo measurements of brain trapping of α-[11C]methyl-L-tryptophan during acute changes in mood states. J Psychiatry Neurosci 2007;32:430-4.

Latest research from computational neuroscience

Another fascinating topic from the SFN Annual Meeting was the research being undertaken in the area of computational neuroscience.

Computational neuroscience is the study of brain function in terms of the information processing properties of the structures that make up the nervous system.

It is an interdisciplinary science that links the diverse fields of neuroscience, cognitive science and psychology with electrical engineering, computer science, mathematics and physics.

In an interview in the current edition of New Scientist, Professor Terry Sejnowski, head of the computational neurobiology lab at the Salk Institute in La Jolla, California, says some of the most intriguing results in computational neuroscience come from collaborations between modelers and experimentalists.

Professor Sejnowski and his research colleagues’ research in modeling signal transfer patterns throughout the brain has resulted in new techniques which make it possible to simultaneously record signals from many neurons. The sensitivity means scientists can for the first time, watch the output from a neuron spread through the brain.

Research has also found that neurons respond differently to different stimuli (for example, signals required to move a prosthetic arm can change when people are tired). This research will help improve brain-machine interferences such as prosthetic limbs and thought-controlled wheelchairs.