Weekly Neuroscience Update

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A network of more than 200 genes encoding proteins with diverse cellular roles was revealed in a non-biased CRISPR screen for regulators of microexon splicing. Many of the genes have previously been linked to autism. Image is credited to Thomas Gonatopoulos-Pournatzis.

Using CRISPR techniques, researchers have uncovered a genetic network linked to autism.

Researchers find evidence of cognitive issues and miRNA biomarkers, indicating brain injuries from concussions or head-to-head contact, in college football players. The findings indicated lasting damage caused by sports-related concussions occur earlier than expected.

A new method for studying the mircobiome has allowed researchers to identify a connection between metabolism in gut bacteria and the development of diabetes.

A new study has identified unique functional brain networks associated with characteristic behaviors of autism spectrum disorder (ASD) in 12- and 24-month old children at risk for developing ASD. The study is published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

Researchers have identified a brain network that may control the diversion of attention to focus on potential threats. Dopamine, they report, is key to the process.

New research has found preliminary evidence that high-intensity interval exercise temporarily impairs reward learning mechanisms in the brain. The research, which was published in Physiology & Behavior, indicates that this type of exercise does not improve all aspects of cognitive function.

A new study reports aerobic exercise can have antidepressant effects for patients with major depressive disorder.

Researchers propose a new theory of human thinking, suggesting our brain’s navigation system is key to thinking. This may explain why our knowledge seems to be organized in spatial fashion.

Scientists have solved a 125-year-old mystery of the brain, and, in the process, uncovered a potential treatment for acquired epilepsy.

A new neuroimaging study reveals the brains of teenage girls who self-harm show similar features to adults with borderline personality disorder.

Researchers were able to distinguish between children with or without ASD diagnosis, thanks to a new saliva-based biomarker panel. Researchers report the test can be used in children as young as 18 month, assisting in early diagnosis of autism.

Finally this week, a new study reveals common brain activity patterns associated with depressive moods.

 

 

 

 

Weekly Neuroscience Update

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A research team has used neuroimaging techniques to investigate how being in a romantic relationship produces alterations in the architecture of the brain. They found that being in love is associated with increased connectivity between regions of the brain associated with reward, motivation, emotion regulation, and social cognition.

Research from McGill University reveals that the brain’s motor network helps people remember and recognize music that they have performed in the past better than music they have only heard.

The human brain can select relevant objects from a flood of information and edit out what is irrelevant. It also knows which parts belong to a whole. If, for example, we direct our attention to the doors of a house, the brain will preferentially process its windows, but not the neighbouring houses. Psychologists have now discovered that this also happens when parts of the objects are merely maintained in our memory.

Researchers have found that teens who smoked marijuana daily for several years have an abnormally shaped hippocampus and do poorly on tasks involving long-term memory.

A new study has shown how intentional recall is beyond a simple reawakening of a memory; and actually leads us to forget other competing experiences that interfere with retrieval.

Researchers have identified key cells within the brain that are critical for determining circadian rhythms, the 24-hour processes that control sleep and wake cycles, as well as other important body functions such as hormone production, metabolism, and blood pressure

New York University researchers have devised a computer model to explain how a neural circuit learns to classify sensory stimuli into discrete categories, such as “car vs. motorcycle.” Their findings, which appear in the journal Nature Communications, shed new light on the brain processes underpinning judgments we make on a daily basis.

Queensland scientists have found that non-invasive ultrasound technology can be used to treat Alzheimer’s disease and restore memory.

Researchers at MIT have developed a method to stimulate brain tissue using external magnetic fields and injected magnetic nanoparticles — a technique allowing direct stimulation of neurons, which could be an effective treatment for a variety of neurological diseases, without the need for implants or external connections.

Researchers have come up with a new way to evaluate how well computers can divine information from images. The team describes its new system as a “visual Turing test,” after the legendary computer scientist Alan Turing’s test of the extent to which computers display human-like intelligence.

Thousands of genetic “dimmer” switches, regions of DNA known as regulatory elements, were turned up high during human evolution in the developing cerebral cortex, according to new research from the Yale School of Medicine.

Finally this week, a new study finds that giving a drug that changes the neurochemical balance in the brain causes a greater willingness to engage in prosocial behaviors, such as ensuring that resources are divided more equally.

Weekly Neuroscience Update

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Carnegie Mellon University neuroscientists have identified a new pathway by which several brain areas communicate within the brain’s striatum.

An over-active habit system may be at the root of many psychological problems involving repetitive behaviours like OCD, alcoholism and binge eating, new research suggests. The neuroimaging study, which is published in the American Journal of Psychiatry, found that people with Obsessive-Compulsive Disorder (OCD) had difficulty controlling their habits.

A new study suggests that the right hemisphere of the brain may be able to assist a damaged left hemisphere in protecting visual attention after a stroke.

Computer based ‘brain training’ can boost memory and thinking skills in older adults, but many programs promoted by the $1 billion brain training industry are ineffective, reveals new research by the University of Sydney.

Researchers have found that navigational brain cells that help sense direction are as electrically active during deep sleep as they are during wake time—and have visual and vestibular cues to guide them. Such information could be useful in treating navigational problems, among the first major symptoms of Alzheimer’s disease and other neurological disorders.

New technology could help researchers advance blood biomarker capabilities that show changes in low concentrations of specific proteins present following a neurological injury.

Our brains generate a constant hum of activity: As neurons fire, they produce brain waves that oscillate at different frequencies. Long thought to be merely a byproduct of neuron activity, recent studies suggest that these waves may play a critical role in communication between different parts of the brain.

Thousands of genetic “dimmer” switches, regions of DNA known as regulatory elements, were turned up high during human evolution in the developing cerebral cortex, according to new research from the Yale School of Medicine.

People with anorexia nervosa and with body dysmorphic disorder have similar abnormalities in their brains that affect their ability to process visual information, a new study reveals.

Finally this week, overall fluid intelligence — the ability to analyze information, engage in critical thinking, and solve problems — is thought to peak in early adulthood, but a new study suggests that different aspects of fluid intelligence peak at different ages.

 

 

 

 

This Is Your Brain On Poetry

poetryResearchers at the University of Exeter have been bridging the gap between art and science by mapping the different ways in which the brain responds to poetry and prose. The team used state-of-the-art functional magnetic resonance imaging (fMRI) technology to visual how the brain activates certain regions to process various activities.

Before this study, no one had specifically examined the brain’s differing responses to poetry and prose. The results, published in the Journal of Consciousness Studies, revealed activity within a “reading network” of brain regions that were activated in response to any written material.

The researchers found that when study participants read one of their favorite passages of poetry, regions of the brain associated with memory were stimulated more strongly than “reading areas.” This suggests that reading a favorite passage is like a recollection. When the team specifically compared poetry to prose, they found evidence that poetry activates brain regions associated with introspection – such as the posterior cingulate cortex and medial temporal lobes.

Weekly Neuroscience Update

The phrase “practice makes perfect” has a neural basis in the brain. Researchers have discovered a set of common changes in the brain upon learning a new skill. They have essentially detected a neural marker for the reorganization the brain undergoes when a person practices and become proficient at a task.

Researchers at the University of East Anglia have made a discovery in neuroscience that could offer a long-lasting solution to eating disorders such as obesity.

A new study conducted by The Mind Research Network , shows that neuroimaging data can predict the likelihood of whether a criminal will reoffend following release from prison.

The ability to communicate in multiple languages not only provides doorways to new cultural and social experiences but also apparently promotes brain growth and staves off the onset of dementia and Alzheimer’s disease.

Researchers have discovered a potential way to decode your dreams, predicting the content of the visual imagery you’ve experienced on the basis of neural activity recorded during sleep.

Brain researchers at Barrow Neurological Institute have discovered that we explore the world with our eyes in a different way than previously thought. Their results advance our understanding of how healthy observers and neurological patients interact and glean critical information from the world around them.

In a study designed to differentiate why some stroke patients recover from aphasia and others do not, investigators have found that a compensatory reorganization of language function to right hemispheric brain regions bodes poorly for language recovery. Patients who recovered from aphasia showed a return to normal left-hemispheric language activation patterns. These results, which may open up new rehabilitation strategies, are available in the current issue of Restorative Neurology and Neuroscience.

 

Weekly Round Up

Welcome to the last weekly round-up of 2011. I have enjoyed putting this together each week and look forward to updating you with lots more new and exciting research in the field of neuroscience in the coming year.

New research has shown, for the first time, that the cortex, which is the largest zone of the brain and which is generally associated with high cognitive functions, is also a key zone for emotional learning.

When you experience a new event, your brain encodes a memory of it by altering the connections between neurons. This requires turning on many genes in those neurons. Now, MIT neuroscientists have identified what may be a master gene that controls this complex process.

A new technique for color-coding nerves involved in touch gives neuroscientists a much-needed tool for studying that mysterious sense.

When accidents that involve traumatic brain injuries occur, a speedy diagnosis followed by the proper treatment can mean the difference between life and death. A research team, led by Jason D. Riley in the Section on Analytical and Functional Biophotonics at the U.S. National Institutes of Health, has created a handheld device capable of quickly detecting brain injuries such as hematomas, which occur when blood vessels become damaged and blood seeps out into surrounding tissues where it can cause significant and dangerous swelling.

Shrinkage in certain parts of the brain may herald Alzheimer’s disease long before symptoms arise, according to new research.

At UCLA’s Laboratory of Integrative Neuroimaging Technology, researchers use functional MRI brain scans to observe brain signal changes that take place during mental activity. They then employ computerized machine learning (ML) methods to study these patterns and identify the cognitive state — or sometimes the thought process — of human subjects. The technique is called “brain reading” or “brain decoding.”

Compared to our other senses, scientists don’t know much about how our skin is wired for the sensation of touch. Now, research reported in the December 23rd issue of the journal Cell, a Cell Press publication, provides the first picture of how specialized neurons feel light touches.

Both children and the elderly have slower response times when they have to make quick decisions in some settings. But recent research suggests that much of that slower response is a conscious choice to emphasize accuracy over speed. In fact, healthy older people can be trained to respond faster in some decision-making tasks without hurting their accuracy – meaning their cognitive skills in this area aren’t so different from younger adults.

Scientists at the University of Cambridge have made a significant step in the development of a novel therapy that could one day help to slow down, or even halt, the damage caused by Parkinson’s disease, one of the most common neurodegenerative disorders.

This is your brain on art

Andy Warhol for Neuroscientists. Image by Valerie van Mulukom

This morning I spent some time looking through the winners of the first annual Brain-Art Competition, a competition designed to “recognize the beauty and creativity of artistic renderings emerging from the neuroimaging community”. This competition aims to recognize the artistic creativity of our community that often goes unappreciated in the publication process.

There are some incredibly visually striking images and you can view an online gallery of these here.