Tag: learning

Weekly Neuroscience Update

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A new study that is the first to compare inflammation and brain stress responses in long COVID-19 patients with individuals who have fully recovered shows that those with continued brain fog and other cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains.

Researchers have identified a remarkably small but critical piece of genetic code that helps determine how brain cells connect, communicate, and function. 

Conditions such as Tourette syndrome (TS), schizophrenia, and attention-deficit/hyperactivity disorder (ADHD) have sex differences with unknown mechanisms. These sex-specific mechanisms may inform the development of more effective treatments.

A new study reveals that type 2 diabetes is associated with thinning of the brain’s cortex in older adults, particularly in regions responsible for memory and cognition. 

Specific cannabinoids produced by the human body may help to quell excessive fear responses in people with post-traumatic stress disorder and anxiety, according to a Northwestern Medicine-led study published in the Journal of Clinical Investigation.

People taking antidepressants for more than two years are more likely to experience withdrawal symptoms compared to short-term users when they come off the medication, finds a new study.

Researchers have identified nine blood-based microRNAs that are elevated in teens diagnosed with depression, offering a potential biomarker for early detection. These molecules, absent in adult depression, may signal unique biological processes in adolescents.

People who have obstructive sleep apnea may have an increased risk of dementia if left untreated, according to a new study of UK electronic health care records.

New research reveals that acute stress can impair key brain functions involved in emotion regulation, particularly in individuals with distress-related disorders like depression, anxiety, and borderline personality disorder. The study found that executive functions—such as working memory, impulse control, and cognitive flexibility—are more likely to be disrupted in these individuals during high-stress moments.

A large-scale study of over 2,500 toddlers found no significant clinical differences in autistic traits between males and females at the time of early diagnosis.

A research team has uncovered the cause and molecular mechanism of chronic brain inflammation that results in repetitive behavioural disorders. The research team demonstrated that an inflammatory response by immune cells in the brain induces overactivity in certain receptors, which may, in turn, lead to the meaningless repetitive behaviours observed in people with autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD).

Measuring the interaction of brain networks could help identify teens at risk for dangerous drinking, according to a novel study that explored how brain signals relate to future drinking behaviour.

In a demographically diverse sample of healthy people, researchers found dramatic changes over the human lifespan in the brain’s “blue spot”—a tiny region involved in cognition and believed to be the first affected by neurodegenerative conditions including Alzheimer’s disease.

Researchers at Karolinska Institutet have identified three types of nerve cells connected to the intestinal villi, suggesting that previously unknown neural networks regulate fluid balance in the gut.

A study in rural China found that intensively lowering blood pressure significantly reduces the risk of dementia and cognitive decline in people with hypertension. Over 48 months, patients who received targeted care saw a 15% reduction in dementia and a 16% drop in cognitive impairment risk.

A new adaptive brain modeling framework offers fresh hope for objective diagnosis of neuropsychiatric disorders, which currently lack reliable neuroimaging biomarkers. 

People who naturally stay up late, are more likely to experience faster cognitive decline than those who are early risers, according to a long-term study. Researchers found that unhealthy behaviors common in the evening, such as poor sleep, smoking, and drinking, may explain part of this risk.

A comprehensive new analysis reveals that depression significantly increases the risk of developing dementia, whether it begins in midlife or later in life.

Researchers have discovered how an ion channel in the brain’s neurons has a kind of “molecular memory,” which contributes to the formation and preservation of lifelong memories. The researchers have identified a specific part of the ion channel at which new drugs for certain genetic diseases could be targeted. The study, led by Linköping University in Sweden, has been published in Nature Communications.

A decade-long brain health study has released its full dataset, offering rare longitudinal insights into how cognition and brain structure change across adulthood.

Neuroscientists have discovered that the brain uses a dual system for learning through trial and error. This is the first time a second learning system has been identified, which could help explain how habits are formed and provide a scientific basis for new strategies to address conditions related to habitual learning, such as addictions and compulsions.

Finally, this week, parental education may protect offspring’s cognitive health later in life, according to a study published online May 30 in JAMA Network Open.

Weekly Neuroscience Update

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A new study that is the first to compare inflammation and brain stress responses in long COVID-19 patients with individuals who have fully recovered shows that those with continued brain fog and other cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains.

Researchers have identified a remarkably small but critical piece of genetic code that helps determine how brain cells connect, communicate, and function. 

Conditions such as Tourette syndrome (TS), schizophrenia, and attention-deficit/hyperactivity disorder (ADHD) have sex differences with unknown mechanisms. These sex-specific mechanisms may inform the development of more effective treatments.

A new study reveals that type 2 diabetes is associated with thinning of the brain’s cortex in older adults, particularly in regions responsible for memory and cognition. 

Specific cannabinoids produced by the human body may help to quell excessive fear responses in people with post-traumatic stress disorder and anxiety, according to a Northwestern Medicine-led study published in the Journal of Clinical Investigation.

People taking antidepressants for more than two years are more likely to experience withdrawal symptoms compared to short-term users when they come off the medication, finds a new study.

Researchers have identified nine blood-based microRNAs that are elevated in teens diagnosed with depression, offering a potential biomarker for early detection. These molecules, absent in adult depression, may signal unique biological processes in adolescents.

People who have obstructive sleep apnea may have an increased risk of dementia if left untreated, according to a new study of UK electronic health care records.

New research reveals that acute stress can impair key brain functions involved in emotion regulation, particularly in individuals with distress-related disorders like depression, anxiety, and borderline personality disorder. The study found that executive functions—such as working memory, impulse control, and cognitive flexibility—are more likely to be disrupted in these individuals during high-stress moments.

A large-scale study of over 2,500 toddlers found no significant clinical differences in autistic traits between males and females at the time of early diagnosis.

A research team has uncovered the cause and molecular mechanism of chronic brain inflammation that results in repetitive behavioural disorders. The research team demonstrated that an inflammatory response by immune cells in the brain induces overactivity in certain receptors, which may, in turn, lead to the meaningless repetitive behaviours observed in people with autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD).

Measuring the interaction of brain networks could help identify teens at risk for dangerous drinking, according to a novel study that explored how brain signals relate to future drinking behaviour.

In a demographically diverse sample of healthy people, researchers found dramatic changes over the human lifespan in the brain’s “blue spot”—a tiny region involved in cognition and believed to be the first affected by neurodegenerative conditions including Alzheimer’s disease.

Researchers at Karolinska Institutet have identified three types of nerve cells connected to the intestinal villi, suggesting that previously unknown neural networks regulate fluid balance in the gut.

A study in rural China found that intensively lowering blood pressure significantly reduces the risk of dementia and cognitive decline in people with hypertension. Over 48 months, patients who received targeted care saw a 15% reduction in dementia and a 16% drop in cognitive impairment risk.

A new adaptive brain modeling framework offers fresh hope for objective diagnosis of neuropsychiatric disorders, which currently lack reliable neuroimaging biomarkers. 

People who naturally stay up late, are more likely to experience faster cognitive decline than those who are early risers, according to a long-term study. Researchers found that unhealthy behaviors common in the evening, such as poor sleep, smoking, and drinking, may explain part of this risk.

A comprehensive new analysis reveals that depression significantly increases the risk of developing dementia, whether it begins in midlife or later in life.

Researchers have discovered how an ion channel in the brain’s neurons has a kind of “molecular memory,” which contributes to the formation and preservation of lifelong memories. The researchers have identified a specific part of the ion channel at which new drugs for certain genetic diseases could be targeted. The study, led by Linköping University in Sweden, has been published in Nature Communications.

A decade-long brain health study has released its full dataset, offering rare longitudinal insights into how cognition and brain structure change across adulthood.

Neuroscientists have discovered that the brain uses a dual system for learning through trial and error. This is the first time a second learning system has been identified, which could help explain how habits are formed and provide a scientific basis for new strategies to address conditions related to habitual learning, such as addictions and compulsions.

Finally, this week, parental education may protect offspring’s cognitive health later in life, according to a study published online May 30 in JAMA Network Open.

Weekly Neuroscience Update

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The four sensory networks of the brain network partition. The partition comprises four sensory networks, with the somatomotor network encompassing the somatosensory cortex. The thalamus contains parcels of each sensory network. Credit: Molecular Psychiatry (2024).

Researchers have uncovered a potential new biomarker for psychosis diagnosis.

A new approach to analyzing brain scans could help researchers better understand psychiatric illness using much smaller groups of patients than previously thought necessary, potentially accelerating the development of more precise mental health treatments.

A new study reveals how specific brain cells called interneurons can act as our in-built traffic controllers. The findings are published in the journal PLOS Biology.

Younger and middle-aged patients seem to be disproportionately affected by neurologic manifestations of post-acute sequelae of severe acute respiratory syndrome coronavirus 2 infection (Neuro-PASC), according to a study published in the Annals of Neurology.

Investigators have defined new biologic and clinical biomarkers for better identifying patients with different stages of Parkinson’s disease and Lewy body dementia.

Researchers have developed the most detailed 3D computational models of key brain regions, including the hippocampus and sensory cortices, to better understand their roles in memory formation and connectivity.

Healing the gut may be the key to improving long-term recovery in stroke patients, scientists at Texas A&M University have found.

New research provides critical insights into the role of sleep in motor learning for individuals recovering from traumatic brain injury (TBI). The study sheds light on how sleep, specifically a short nap, influences brain activity associated with motor skill improvement, with implications for optimizing rehabilitation strategies.

A recent study of high school football players found that concussions affect an often-overlooked but important brain signal.

Researchers have uncovered that stress changes how our brain encodes and retrieves aversive memories, and discovered a promising new way to restore appropriate memory specificity in people with post-traumatic stress disorder (PTSD).

Cognitive neuroscientists at Trinity College Dublin have published new research describing a brand new approach to making habit change achievable and lasting.

A new study uncovers constant communication between the human brain’s social cognitive network, responsible for understanding others’ thoughts, and the amygdala, known for processing fear and emotions. High-resolution brain scans revealed that this connection helps the brain integrate emotional importance into social interactions. This insight could lead to non-invasive treatments like transcranial magnetic stimulation (TMS) for anxiety and depression by targeting these regions. The findings highlight how evolutionary brain expansion enhances social understanding while linking it to ancient emotional processing centers.

Neuroscientists have demonstrated that dopamine and serotonin work in opposition to shape learning.

Researchers have identified a novel role for the brain’s ‘locus coeruleus’ in sleep and its disruptions. This brain region facilitates the transition between NREM and REM sleep states while maintaining an unconscious vigilance toward the external world. Stress disrupts its functions and negatively impacts on sleep quality.

A future treatment for Alzheimer disease may involve a nasal spray. 

A new method to profile gene activity in the living human brain has been developed by researchers at FutureNeuro, the Research Ireland Center for Translational Brain Science and RCSI University of Medicine and Health Sciences, in collaboration with international partners. This innovative approach, published in JCI Insight, opens new avenues for understanding and treating neurological conditions such as epilepsy.

A study led by the University of Glasgow has revealed differences in the brains of pediatric and adult patients that might explain the sometimes catastrophic outcomes seen in children following a traumatic brain injury.

Finally this week, new research has examined the relationship of emotion regulation to real-world responses to stress to better understand stress-related increases in suicide risk in depression.

World Teacher’s Day: What Can Neuroscience Teach Us About Teaching?

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What if we could unlock the secrets of the human brain to revolutionize how we teach and learn?

A new science of learning is emerging, fueled by converging insights from fields like developmental psychology, machine learning, and neuroscience. This field is uncovering the biological, cognitive, and social factors that influence how we learn, paving the way for more effective teaching practices and improved learning outcomes. For instance, we now understand the importance of active learning, where students are engaged and challenged to construct their own knowledge rather than passively absorbing information. We also recognize the powerful role emotions play in learning. Positive emotions enhance learning while negative emotions like stress can hinder it, highlighting the need for supportive and engaging learning environments. Furthermore, this new science emphasizes the importance of personalized learning, recognizing that each student learns in their own unique way.

Optimizing Learning by Targeting Different Memory Systems

Neuroscience has shown us that memory is more complex than we once thought. It’s not just one thing, but a system of different types, each with its own job and connected to different parts of the brain.

Episodic memory is like a mental scrapbook. It helps us remember past experiences, like a fun school trip or a birthday party. Teachers can tap into this by using techniques that emphasize narrative construction, real-world applications, and the establishment of personal connections with the subject matter.

Semantic memory is our storehouse of facts and concepts. It’s how we remember things like state capitals or the rules of gravity. Teachers can help students build this type of memory by using visuals, diagrams, and clear explanations.

Procedural memory is all about skills. It’s how we learn to ride a bike or play an instrument. To get better at these things, we need practice, feedback, and to learn skills step-by-step.

Understanding these different memory systems can really change how we teach. When teachers know which type of memory is involved in a lesson, they can plan activities that make it easier for students to learn, remember, and use information.

The Adolescent Brain: A Period of Continued Development

Contrary to earlier assumptions, brain development is not confined to childhood. The prefrontal cortex, the brain’s executive control center responsible for planning, decision-making, and impulse inhibition, continues to mature well into early adulthood, typically around 20-25 years of age. This protracted developmental trajectory explains why adolescents often grapple with impulse control, risk assessment, and delaying gratification. They may engage in actions without fully considering the consequences, undertake risks without a complete understanding of potential dangers, or encounter difficulties prioritizing long-term goals over immediate rewards.

This understanding holds significant implications for educators. It underscores the necessity for patience and support as adolescents navigate the complexities of this developmental period. By providing structured environments, clear expectations, and opportunities to cultivate self-regulation techniques such as mindfulness or organizational strategies, educators can facilitate the strengthening of the prefrontal cortex and the development of essential life skills.

Neuroeducation: Bridging Neuroscience and Education

For much of recent history, the fields of neuroscience and education operated in distinct domains, with limited interaction between researchers. However, this began to shift in the 1990s with the growing recognition of the brain’s remarkable plasticity—its capacity to reorganize and adapt throughout the lifespan in response to experiences. This discovery, coupled with advancements in neuroimaging techniques, fueled increasing interest in how insights from neuroscience could inform and enhance educational practices, ultimately leading to the emergence of neuroeducation.

Neuroeducation is an interdisciplinary field that strives to bridge the gap between neuroscience and education. It investigates how the brain learns, remembers, and processes information, and applies these findings to develop more effective pedagogical approaches. By understanding the neural mechanisms underlying learning and cognition, educators can create learning environments that optimize brain function and promote deeper understanding. For instance, incorporating movement breaks into lessons can capitalize on the benefits of physical activity for cognitive function, while integrating mindfulness practices can assist students in managing stress and enhancing focus.  

Neuroeducation emphasizes that learning is not a passive process of absorption but rather an active process that induces physical changes in the brain. Every new experience, every acquired skill, every learned fact—all leave their imprint on the brain’s intricate neural networks. This knowledge empowers educators to design learning experiences that leverage the brain’s inherent learning processes. Examples include incorporating spaced repetition into lesson plans to enhance memory consolidation or utilizing storytelling to engage the emotional dimensions of learning.  

The goals of neuroeducation are far-reaching. It aims to improve educational outcomes for all learners, address learning challenges and disabilities such as dyslexia or ADHD, promote creativity and innovation in educational settings, and foster a lifelong love of learning. While a relatively nascent field, neuroeducation holds immense potential to transform educational practices and positively impact learners of all ages.  

Neuroeducation: Integrating Neuroscience and Artificial Intelligence in Educational Practice

Augmenting the progress of neuroeducation is the advent of artificial intelligence (AI), which presents transformative potential for educational practices. Imagine AI systems functioning as personalized learning guides, identifying each student’s unique learning style, strengths, and areas for improvement. With this insight, AI can create custom-tailored learning plans, perfectly suited to each student’s needs. AI tutors can then step in, providing real-time support, feedback, and challenges that adapt to the student’s progress—keeping them both engaged and motivated. AI-powered games and simulations also turn learning into an immersive experience, designed to match each student’s pace and interests.

AI is also changing how we assess learning. By analyzing work products like essays or problem-solving exercises, AI can pinpoint areas that need further attention and deliver targeted, constructive feedback. It can even assess a learner’s emotional state and engagement during lessons, enabling teachers to adjust their instructional methods for optimal impact.

Looking ahead, brain-computer interfaces (BCIs) could allow our brains to interact directly with computers. This technology could be life-changing for students with disabilities, giving them new ways to control devices and communicate. BCIs could also provide real-time feedback on brain activity during learning, helping students improve their focus and self-regulation.

Despite these exciting possibilities, the integration of AI in neuroeducation comes with significant ethical and practical challenges. Protecting student data must be a top priority, necessitating AI systems that are built with privacy at their core. Equitable access to AI tools is also crucial to prevent exacerbating existing achievement gaps. Furthermore, teachers will need comprehensive training to effectively incorporate AI technologies into their classrooms. Striking a balance between technological innovation and human interaction is essential to maintaining the critical role of educators in fostering well-rounded student development.

Curiosity, interest, joy, and motivation—these are the cornerstones of effective learning. Neuroeducation, with its focus on understanding the brain’s role in learning, combined with AI’s innovative potential, offers a path toward a more personalized, engaging, and inclusive educational future.

Further Reading: What can neuroscience teach us about teaching?

Weekly Neuroscience Update

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Findings from a mega-analysis of differences in seed-based subcortico-cortical connectivity in youths with attention deficit hyperactivity disorder (ADHD) and unaffected control subjects. Credit: American Journal of Psychiatry (2024). 

Researchers have discovered that symptoms of attention-deficit/hyperactivity disorder (ADHD) are tied to atypical interactions between the brain’s frontal cortex and information-processing centers deep in the brain.

A new study has identified a genetic mutation underlying a rare form of epilepsy and reveals novel molecular and cellular mechanisms by which the disorder manifests in patients.

For the first time, researchers have shown that non-invasive brain stimulation can change a specific brain mechanism directly related to human behavior. This is a major step forward for discovering new therapies to treat brain disorders such as schizophrenia, depression, Alzheimer’s disease, and Parkinson’s disease.

A test that shows how good or bad we are at perceiving the rhythm of language can predict the ability to acquire language, and may also help us understand individual differences in brain biology.

A new study reveals the mechanisms behind proprioception, our body’s innate ability to sense limb position and movement, critical for movement without visual cues. Utilizing musculoskeletal simulations and neural network models, researchers have advanced our understanding of how the brain integrates sensory data from muscle spindles to perceive bodily position and motion.

Specialized brain scans may accurately predict whether a psychotic patient will go on to develop treatment-resistant schizophrenia, Dutch researchers report.

Researchers have uncovered a significant correlation between social isolation and accelerated biological aging, indicating that individuals with limited social connections are at a higher risk of premature mortality.

Scientists have revealed new insights into how the brain processes speech and listening during conversations through advanced investigations using functional magnetic resonance imaging (fMRI).

A unique multicenter study, including about 3,500 youth between 10 and 25 years old from across the globe, shows that artificial intelligence—specifically machine learning—can identify individuals with anxiety disorders based on their unique brain structure.

Researchers have identified four distinct sleep patterns linked to long-term health outcomes, revealing the profound impact of sleep habits on chronic health conditions.

A new study uncovers the nuanced effects of spaced learning on memory, emphasizing the importance of the content’s variability and the intervals between learning sessions. The study contrasts the impact of learning identical content versus content with variations, across different timescales, on memory retention.

Finally, this week, spending quality time with dogs reduces stress and increases the power of brain waves associated with relaxation and concentration, according to a recent study.

The Surprising Power of Forgetfulness

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This video explores the storage, suppression, and rekindling of memories, drawing upon groundbreaking research from Trinity College Dublin.

In pursuit of perfect memory, we tend to categorize forgetfulness as a sign of cognitive weakness. However, emerging research suggests a paradigm shift in our understanding of memory and forgetfulness. In contrast to popular belief, forgetting is not a sign of a faulty memory, but rather the brain orchestrating a purposeful act to optimize our cognitive abilities.

This shift could revolutionize the way we perceive memory and its role in our daily lives. Instead of viewing forgetfulness as a shortcoming, it could be seen as a strategic mechanism, honed by evolution to filter and prioritize information. Imagine the implications this could have on education, where traditional methods often emphasize rote memorization. If forgetting is indeed a natural and adaptive process, educators might need to reconsider their approach to learning and information retention.

Furthermore, the understanding of forgetting and its purpose can hold profound implications for disciplines such as psychology and neurology. Expanding our comprehension of the mechanisms and functions of forgetting may serve to reshape the approaches taken toward memory-related disorders and therapeutic interventions. This, in turn, could potentially open up new avenues for research and treatment, propelling advancements in these crucial fields.

Neuroplasticity at Work
Neuroplasticity, the brain’s ability to reorganize itself by forming new neural connections, plays a pivotal role in understanding the purposeful nature of forgetfulness. In a world where information overload is a daily reality, the brain must prioritize and organize data to function efficiently. This remarkable ability allows the brain to filter out irrelevant information and focus on what’s essential. The brain’s plasticity enables it to form new neural connections and reorganize existing ones, facilitating adaptation to new environments and learning new skills. Understanding the brain’s capacity for adaptation and prioritization sheds light on its incredible resilience and capability to thrive in diverse and demanding circumstances.

Learning from Mistakes
Forgetfulness also serves as a valuable tool in learning from our mistakes. It allows us to filter out the less important information and retain only the most crucial lessons from our experiences. This process of selective forgetfulness aids in simplifying complex situations and extracting the key takeaways, ultimately contributing to a more refined learning process. By discarding superfluous details, our minds are better equipped to discern patterns and identify the core factors that contributed to specific outcomes. This, in turn, empowers us to make more informed decisions in the future and navigate similar situations more effectively. It’s fascinating to consider how our brains have evolved this adaptive mechanism to optimize the learning process and enable us to continuously improve our responses to various challenges.

The Role of Emotions
Emotions play a significant role in the encoding and retrieval of memories. The brain tends to retain emotionally charged experiences more vividly, while less emotionally significant details may fade away. Forgetfulness, therefore, is not an indiscriminate process but rather a nuanced response influenced by the emotional context of our memories. This phenomenon highlights the interconnectedness of our emotional experiences and memory formation. The amygdala, a key player in processing emotions, is closely linked to the encoding and storage of emotional memories. When we encounter a particularly emotional event, the amygdala sends a signal to the hippocampus, a region crucial for forming new memories, enhancing the vividness and strengthening the imprint of that experience in our minds.

Understanding the impact of emotions on memory not only provides insight into the workings of the human mind but also has practical implications. For instance, educators can leverage emotionally charged experiences to enhance students’ retention of material. Similarly, in therapeutic settings, acknowledging the emotional context of memories is essential to address and process traumatic experiences effectively.

In reevaluating our understanding of forgetfulness, it becomes clear that our brains are not simply fallible machines prone to glitches. Instead, forgetfulness is a purposeful act orchestrated by our brains to optimize cognitive function in an ever-changing environment. When we consider the concept of forgetfulness in this light, we start to recognize the remarkable abilities of our brains to prioritize and adapt in response to the constant influx of new information and experiences. Rather than viewing forgetfulness as a shortcoming, we can appreciate it as a strategic process that allows our minds to maintain efficiency and relevance in a dynamic reality. This perspective invites us to explore the interplay between forgetting and remembering, shedding light on the delicate balance that sustains our cognitive prowess.

Weekly Neuroscience Update

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Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-42088-7

A team of international neuroscientists has obtained the first direct recordings of the human brain in the minutes before and after a brain hub crucial for language meaning was surgically disconnected. The results reveal the importance of brain hubs in neural networks and the remarkable way in which the human brain attempts to compensate when a hub is lost, with immediacy not previously observed.

A new study, published in Cell Reports, describes a novel molecular link between vitamin B12 and multiple sclerosis that takes place in astrocytes—important non-neuronal glial cells in the brain.

Australian researchers have flagged potential concerns over the use of social chatbots, calling for more studies into the impact of AI software on neurodiverse people and those who find human interaction difficult.

An exploratory study has shown that light, regular exercise can improve the cognitive as well as physical health of adults with Down syndrome.

Researchers at Linköping University, Sweden, have examined the brains of 16 patients previously hospitalised for COVID-19 with persisting symptoms. They have found differences in brain tissue structure between patients with persisting symptoms after COVID-19 and healthy people.

Scientists have discovered a new way a ribonucleic acid (RNA) impacts fear-related learning and memory.

Comparing PET scans of more than 90 adults with and without mild cognitive impairment (MCI), researchers say relatively lower levels of the so-called “happiness” chemical, serotonin, in parts of the brain of those with MCI may play a role in memory problems including Alzheimer’s disease.

A new study reveals a significant association between adverse childhood experiences and symptoms of muscle dysmorphia in adolescents and young adults.

Using electrochemical techniques and machine learning, scientists measured dopamine levels in real time during a computer game involving rewards and penalties. The findings shed light on the intricate role of dopamine in human behavior and could have implications for understanding psychiatric and neurological disorders.

Researchers have identified a potential treatment target for a genetic type of epilepsy.

A new study sheds light on the significant role of patients’ beliefs in the effectiveness of neurostimulation treatments for conditions like depression and ADHD. Analyzing five studies, the research team found that patients’ perceptions of receiving real or placebo treatments often had more impact on outcomes than the treatments themselves.

New research has found that smoking causes the brain to shrink and age prematurely, a condition not reversible even after quitting smoking.

Researchers have discovered a key player in alcohol addiction: pituitary adenylate cyclase-activating polypeptide (PACAP). This peptide, found in the “bed nucleus of the stria terminalis” (BNST), is linked to heavy alcohol drinking and withdrawal.

Finally this week, new research reveals that moderate exercise improves cognitive performance even under conditions of sleep deprivation and low oxygen levels.

Unraveling The Mysteries of Dopamine [Video]

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Drawing on a recent groundbreaking study, this video explores how dopamine operates within the paradigms of Pavlovian and operant conditioning. The study provides new insights into the intricate functionality of this essential neurotransmitter in the brain.

Classical conditioning, also known as Pavlovian conditioning, involves learning through associations between a neutral stimulus and an unconditioned stimulus. In this process, dopamine release is triggered when the neutral stimulus becomes associated with a reward or positive outcome. Dopamine helps in reinforcing the connection between the neutral stimulus and the reward, making the association stronger.

Dopamine is closely linked to reward learning and motivation. It is involved in the brain’s reward system, which helps in reinforcing behaviors that lead to pleasurable experiences or rewards. Dopamine release signals to the brain that a certain action or behavior is beneficial and should be repeated. It provides a sense of satisfaction and drives motivation to engage in actions that lead to positive outcomes.

Watch the video to explore:

🔹 What triggers dopamine release?

🔹 The difference between classical and Pavlovian conditioning.

🔹 The pivotal role of dopamine in reward learning and motivation.

🔹 Which disease is associated with a lack of dopamine.

🔹 How antipsychotics impact dopamine.

Weekly Neuroscience Update

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Researchers have presented new findings which found after one session of aerobic exercise people showed reduced cravings for alcohol, lower levels of stress, and improvements in mood.

When our eyes move during REM sleep, we’re gazing at things in the dream world our brains have created, according to a new study. The findings shed light not only into how we dream, but also into how our imaginations work.

Measuring how the eyes’ pupils change in response to light—known as the pupillary light reflex—could potentially be used to screen for autism in young children, according to a new study.

Researchers have made an important discovery about the way our brains process the sensations of sound and touch. They found that sensory systems in the brain are closely interconnected, with regions that respond to touch also involved when we listen to specific sounds connected to touching certain objects.

A study into the effect of surprise on our memory has inadvertently discovered a method that might help us to perform better in exams.

Scientists have uncovered how dopamine connects subregions of the striatum essential for habit formation, findings that may change the overall understanding of how habits are formed—and could be broken.

New research finds the brains of people playing online video games synchronize, even when there is a physical distance between the players.

By estimating people’s brain age from MRI scans using machine learning, a team of researchers has identified multiple risk factors for a prematurely aging brain. They found that worse cardiovascular health at age 36 predicted a higher brain age later in life, while men also tended to have older brains than women of the same age, as they report in The Lancet Healthy Longevity.

Young people with 22q11.2 Deletion Syndrome have distinct and marked EEG differences in brain activity during sleep, which could influence psychiatric symptoms.

Tight control of blood sugar in teens with Type 1 diabetes may help reduce the disease’s damaging effects on the brain, effects which have been shown even in younger children, according to a study published in Nature Communications.

Tests of the brain’s electrical activity have revealed fentanyl’s effects over time and indicated that the drug stops people’s breathing before other noticeable changes and before they lose consciousness.

A newly developed artificial intelligence model can detect Parkinson’s disease by reading a person’s breathing patterns. The algorithm can also discern the severity of Parkinson’s disease and track progression over time.

A new study reveals how a molecule produced by astrocytes interferes with normal neuron development in a range of neurodevelopmental disorders.

People with an obsessive urge to constantly check the news are more likely to suffer from stress, anxiety, as well as physical ill health, finds a new study published in the peer-reviewed journal Health Communication.

Finally this week, the impact of breathing diesel exhaust fumes may be more severe for females than males, according to new research.

Weekly Neuroscience Update

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New artificial intelligence technology reveals previously unknown cell components. The findings may shed new light on human development and diseases.

A new mathematical model explains how the brain has the ability to continuously acquire new skills, specifically movement-based skills, without forgetting or degrading old ones. The theory, dubbed COIN, suggests identifying current context is key to learning how to move our bodies when acquiring skills.

Playing video games that are heavy on action can make you better at some new tasks. New research reveals that these games are helping by teaching players to be quicker learners.

The “background noise” in the brain disrupts long-memory signals by neurons. This noise interrupts the consistent rhythm of long-memory alpha wave signals in people experiencing identity confusion.

Memory errors may indicate a way in which the human cognitive system is optimally running, researchers say.

Housework is linked to sharper memory, attention span, and better leg strength, and by extension, greater protection against falls, in older adults, finds research published in the open access journal BMJ Open.

Repetitive transcranial magnetic stimulation (rTMS) can be used to modulate brain rhythms and cognitive behaviors related to “giving up” during problem-solving tasks.

New research reveals that specialized cells within neural circuitry that triggers complex learning in songbirds bears a striking resemblance to a type of neural cell associated with the development of fine motor skills in the cortex of the human brain.

Finally this week, a new study links a propensity to binge-watch TV shows with personality traits. Researchers found those who lack impulse control and emotional clarity are most likely to binge-watch a television series.