Weekly Neuroscience Update

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In a new study, researchers identified the most common characteristics of 85 COVID-19 patients who died in Wuhan, China in the early stages of the coronavirus pandemic. The study reports on commonalities of the largest group of coronavirus patient deaths to be studied to date.

Abnormal blood clotting contributes to death in some patients with severe COVID-19 infections.

A newly developed blood test for Alzheimer’s disease measures a specific variant of the tau protein. Early results show the test has a good capacity to distinguish Alzheimer’s disease from other tauopathies.

New findings support the theory that impaired prefrontal control of the dopamine system is a key mechanism for the development of schizophrenia.

Researchers report that in depressed individuals there are increased amounts of an unmodified structural protein, called tubulin, in lipid rafts — fatty sections of a cell membrane — compared with non-depressed individuals.

A new genetics test for COVID-19 has been developed by an international team of researchers. 

Genetic variability in the human immune system may affect susceptibility to, and severity of infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for the coronavirus disease (COVID-19).

Researchers have developed a new approach to prevent amyloid plaque formation by engineering a nanodevice that captures the peptides before they can assemble.

A new study puts into question conventional belief that the eyes communicate with the brain exclusively via one signaling pathway. Researchers have identified a subset of retinal neurons that sends inhibitory signals to the brain. This subset of neurons is also involved in the synchronization of circadian rhythms to light/dark cycles and pupil constriction to bright light intensity.

Finally, this week, a new study sheds light on the role brain insulin plays in weight and visceral fat accumulation.

Weekly Neuroscience Update

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Researchers have created a new technique that can rapidly “print’ two-dimensional arrays of cells and proteins that mimic a variety of cellular environments in the body.
 

People who develop Parkinson’s disease before age 50 may have been born with disordered brain cells that went undetected for decades, according to new research. The research points to a drug that potentially might help correct these disease processes.

A new substance named Lu AF60097 may help reduce side effects from tricyclic antidepressants in those with severe depression.

Researchers have uncovered a key role of medial prefrontal cortex corticotropin-releasing factor interneurons for bidirectionally controlling motivated behavioral styles under stress. The findings could help in the development of new treatments for PTSD.

MIT researchers have identified a protein fragment that may inhibit COVID-19’s ability to enter human lung cells. 

Researchers have developed a new method to record brain activity at scale. The new technique could help in the development of new neuroprosthetic devices to help amputees and those with movement restricting neurological conditions.

New research suggests that eye movements may come before hand movements in actions that require a two-step decision-making process. 

A new method to accurately record brain activity at scale has been developed by researchers. The technique could lead to new medical devices to help amputees, people with paralysis or people with neurological conditions such as motor neuron disease.

Stress, loneliness, and sleep loss can weaken the immune system, leaving people more susceptible to COVID-19.

Finally this week. using robotics, researchers have uncovered mechanisms in the cerebellum and spinal cord that determine how the nervous system responds to induced changes in step length. The findings could have implications for physical rehabilitation programs for people with movement disorders.