Weekly Neuroscience Update

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Researchers explore how memory consolidation occurs during sleep.

Fetal brains use a special amplifier in order to transmit signals, according to research published in the journal eLife.

Scanning ultrasound appears to slow down ageing in healthy brains, a new study reports.

Two interconnected brain areas – the hippocampus and the entorhinal cortex – help us to know where we are and to remember it later. By studying these brain areas, researchers have uncovered new information about how dysfunction of this circuit may contribute to memory loss in Alzheimer’s disease. Their results appear in Cell Reports.

A new tool is allowing researchers to interactively explore the hierarchical processes that happen in the brain when it is resting or performing tasks.

Researchers have identified a set of heat sensing neurons that prompt both nervous system and behavioral changes that help cool the body.

As estrogen levels rise in women, the volume of the hippocampus increases, a new study reports.

A new study reports on how the perceptual mechanisms in a person’s brain adapt in response to images of one’s own or other people’s bodies that have been manipulated to look thinner or fatter than they really are

Researchers have found evidence that challenges the intuitive division between a ‘deciding’ and a ‘responding’ stage in decision making.

Finally this week, a new method for inducing, modelling and measuring visual hallucinations in healthy individuals suggests these complex experiences share a common underlying mechanism with normal visual perception.

 

Weekly Neuroscience Update

Nerve cells communicate with each other via intricate projections. In brain diseases such as Alzheimer’s and Parkinson’s these extensions atrophy, thereby causing connectivity problems. Credit DZNE/Detlef Friedrichs.

Nerve cells communicate with each other via intricate projections. In brain diseases such as Alzheimer’s and Parkinson’s these extensions atrophy, thereby causing connectivity problems. Credit DZNE/Detlef Friedrichs.

A new study shows the interdependency between the structure and function of neurons.

Neuroscientists have discovered an unexpected benefit of getting older – a more nuanced understanding of social signals, such as the age of others.

Children with autism show different patterns of brain activity during everyday gestures and movements than controls do, suggest unpublished results presented at the 2014 Society for Neuroscience annual meeting.

Researchers have gained fresh insights into how ‘local’ body clocks control waking and sleeping.

People with bipolar disorder who are being treated with the drug lithium are at risk of acute kidney damage and need careful monitoring, according to new research.

Age-related Macular Degeneration (AMD) is the major cause of blindness in the western world, affecting around 50 million people. Now scientists at The University of Manchester have identified an important new factor behind its causes, which they hope could lead to new treatments.

A team of researchers has identified an enzyme key to the survival and spread of glioblastoma cancer cells that is not present in healthy brain cells, making the enzyme a promising therapeutic target.

It is claimed one in five students have taken the ‘smart’ drug Modafinil to boost their ability to study and improve their chances of exam success. But new research into the effects of Modafinil has shown that healthy students could find their performance impaired by the drug.

Researchers have developed new insight into a rare but deadly brain infection, called progressive multifocal leukoencephalopathy (PML). This disease – which is caused by the JC virus – is most frequently found in people with suppressed immune systems and, until now, scientists have had no effective way to study it or test new treatments.

New research offers insight into short-term effects of maternal caregiving on a developing brain.

A team of researchers  has now been able to demonstrate in a study that the bonding hormone oxytocin inhibits the fear center in the brain and allows fear stimuli to subside more easily. This basic research could also usher in a new era in the treatment of anxiety disorders.

Blocking a key receptor in brain cells that is used by oxygen free radicals could play a major role in neutralizing the biological consequences of Alzheimer’s disease, according to new research.

Finally this week, brain scientists have long believed that older people have less of the neural flexibility (plasticity) required to learn new things. A new study shows that older people learned a visual task just as well as younger ones, but the seniors who showed a strong degree of learning exhibited plasticity in a different part of the brain than younger learners did.

 

Saving Brains, A Grand Challenge

Food for thought about investing in the future of our children, in this video by Dr. Mike Evans, founder of the Health Design Lab at the Li Ka Shing Knowledge Institute, an Associate Professor of Family Medicine and Public Health at the University of Toronto, and a staff physician at St. Michael’s Hospital.

Weekly Neuroscience Update

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Johns Hopkins researchers report that people with chronic insomnia show more plasticity and activity than good sleepers in the part of the brain that controls movement.

Researchers at The Scripps Research Institute (TSRI) and Vanderbilt University have created the most detailed 3-D picture yet of a membrane protein that is linked to learning, memory, anxiety, pain and brain disorders such as schizophrenia, Parkinson’s, Alzheimer’s and autism.

New research has revealed the dramatic effect the immune system has on the brain development of young children. The findings suggest new and better ways to prevent developmental impairment in children in developing countries, helping to free them from a cycle of poverty and disease, and to attain their full potential.

Rate of change in the thickness of the brain’s cortex is an important factor associated with a person’s change in IQ, according to a collaborative study by scientists in five countries.

Researchers have found that decision-making accuracy can be improved by postponing the onset of a decision by a mere fraction of a second. The results could further our understanding of neuropsychiatric conditions characterized by abnormalities in cognitive function and lead to new training strategies to improve decision-making in high-stake environments. The study was published in the March 5 online issue of the journal PLoS One.

A study has revealed how the fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is transmitted from cell to cell, and suggests the spread of the disease could be blocked.

Research from Karolinska Institutet in Sweden suggests that the expression of the so called MYC gene is important and necessary for neurogenesis in the spinal cord. The findings are being published in the journal  EMBO Reports .

Our memories are inaccurate, more than we’d like to believe. And now a study demonstrates one reason: we apparently add current experiences onto memories.

Damage to the brain may still occur even if symptoms of traumatic brain injury are not present, scientists suggest.

The brain processes read and heard language differently. This is the key and new finding of a study published in Frontiers in Human Neuroscience.

Is the internet changing your brain?

Is the internet changing the way we think?

This Saturday, 11 June, I am looking forward to giving a talk at 3D Camp at the University of Limerick on how the internet is changing our brain. I will be exploring the question of whether our brains are being altered due to our increasing reliance on search engines, social networking sites and other digital technologies.

Using a basic understanding of brain structure (neurology) I will explain the concept of ‘brain plasticity’- the ability of the brain to constantly rewire itself – and will show how all learning changes the shape of the brain, allowing specific areas in the brain to grow or change. I will also be demonstrating how the new ‘cybertherapies’ are being used to help patients suffering from addiction and post traumatic stress disorder back to health.  I believe this new resource has the potential to dramatically improve mental health including new opportunities to learn healthy habits to lift our mood and enhance our brains longevity.

There are still places left on this themed Barcamp which looks at The Internet Beyond Web 2.0. Areas. Attendance is FREE! 

Click here to register

Stroke recovery boosted by Prozac

Stroke is the third biggest killer disease in Ireland – over 2,000 people die per year – causing more deaths than breast cancer, prostate cancer and bowel cancer combined. Up to 10,000 people will suffer a stroke in Ireland this year and one in five people will have a stroke at some time in their life.

An unexpected new finding for antidepressant drugs and a very important one.

Findings from the largest study of selective serotonin re-uptake inhibitors (SSRIs) and stroke report that giving stroke patients the antidepressant drug Prozac soon after the event helps their recovery from paralysis. A total of 118 French patients were involved in the study. The beneficial effects of the drug – more improvement in movement and greater independence – were seen after three months – helping patients gain independence. This finding suggests that this already licensed drug – also known as fluoxetine – could have a dual benefit in the treatment of acute ischemic stroke – that’s where blood flow and oxygen supply to the brain are impaired.

Antidepressant drugs can help neurons to grow

One theory about how antidepressants may help brains recover more quickly from stroke is that they encourage neurogenesis – the creation of new neurons – in particular in the hippocampus – a brain region implicated in emotion especially anxiety – an emotion which can wear down even the most resilient person.

The ability of antidepressant drugs to increase neuron growth and connections – brain plasticity – is a promising pathway for treatment of patients with ischemic stroke and moderate to severe motor deficit. It’s a controversial theory and so far it only appears to hold true in young mice. In middle-aged and older mice, no such neurogenesis was observed – so there may be another mechanisms operating. 

One thing is for sure – it’s an important finding and I hope we’ll see more work on this.