Weekly Neuroscience Update

Credit: Nature Mental Health (2025)

Pioneering research has identified the brain mechanisms that enable psychosis to remit. These findings could significantly inform the development of novel intervention strategies for patients with psychosis.

Contrary to fears of “digital dementia,” new research finds that using digital technology is linked to a reduced risk of cognitive decline in older adults. A large-scale meta-analysis of over 400,000 participants revealed that digital engagement correlates with a 58% lower risk of cognitive impairment.

A simple method of brain stimulation has been shown to change how people make decisions. These were the findings of a new study published in the Journal of Cognitive Neuroscience.

A team of researchers has identified the key brain regions that are essential for logical thinking and problem solving. The findings help to increase our understanding of how the human brain supports our ability to comprehend, draw conclusions, and deal with new and novel problems—otherwise known as reasoning skills.

Medial temporal lobectomy is effective in improving seizure outcomes among patients with drug-resistant temporal lobe epilepsy, according to a recent study.

New research links fatty, sugary diets to impaired brain function. The findings build on a growing body of evidence showing the negative impact of high-fat, high-sugar (HFHS) diets on cognitive ability, adding to their well-known physical effects.

A recent study reveals that the basolateral amygdala plays a key role in calibrating prosocial behavior based on emotional closeness.

New research reveals that gut imbalances in children with autism may influence brain activity and behaviour by disrupting the production of key neurotransmitters like serotonin. Scientists found that changes in gut-derived metabolites are linked to differences in brain structure and function in children with autism.

Chronic pain is closely intertwined with depression. Individuals living with pain’s persistent symptoms may be up to four times more likely to experience depression according to a new study.

Our brains can adapt to filter out repeated distractions, according to a new EEG study. Participants learned to ignore frequent visual distractions, such as a red shape in the same location, while searching for a target.

Repetitive transcranial magnetic stimulation is showing promise in Alzheimer’s treatment.

A new international study reveals a possible connection between GLP1 receptor agonists—used in drugs like Ozempic—and increased risk of depression and suicidal ideation, especially in people with low dopamine function.

Researchers have found a potential link between the trauma of climate-related events, exemplified by devastating wildfires, and persistent effects on cognitive function.

Researchers have developed a personalized blood test that may offer a faster, less invasive way to track high-grade glioma progression. By identifying unique DNA junctions from each patient’s tumour, the test can detect tumor DNA in the bloodstream, even before changes appear on MRI scans.

A new study demonstrates for the first time that listening to favorite music activates the brain’s opioid receptors.

Promising a more personalized approach to treating major depressive disorder (MDD), a new study reveals that brain connectivity patterns, especially in the dorsal anterior cingulate cortex, can significantly predict patient response to antidepressant medications. This finding was validated in two large, independent clinical trials using brain imaging and clinical information.

Contrary to potential assumptions, recent research demonstrates that the spatial working memory of older people with autistic traits and neurotypical individuals shows no difference in change over time.

A major international study has provided the most comprehensive evidence to date on treatments for neuropathic pain —defined as pain caused by disease of the nervous system, affecting up to 10% of the population worldwide.

Finally, this week, exercise appears to be vital for maintaining sharp minds, even when a key brain energy source is lacking, according to a new study.

Weekly Neuroscience Update

Single-trial dynamics in LIP and SC are different. (Neuron, 2023)

A new paper, published in Neuron, highlights the role of the superior colliculus (SC), a structure in the midbrain, in terminating decisions.

Degeneration of dopaminergic neurons is widely accepted as the first event that leads to Parkinson’s, but a new study suggests that a dysfunction in the neuron’s synapses—the tiny gap across which a neuron can send an impulse to another neuron—leads to deficits in dopamine and precedes the neurodegeneration.

Depression, a challenging condition to diagnose early, may now be detected more promptly using a simple 1-minute Electroencephalogram (EEG) test at home.

Scientists have confirmed that human brains are naturally wired to perform advanced calculations, much like a high-powered computer, to make sense of the world through a process known as Bayesian inference.

New research shows how repeated traumatic brain injury contributes to Alzheimer’s disease.

Racial disparities can be seen in dementia severity, functional impairment, and neuropsychiatric symptoms among patients with frontotemporal dementia (FTD), according to a study recently published in JAMA Neurology.

A new study identifies a potential new approach to PTSD treatment.

Any head injury—even a mild one—raises a person’s risk of later having an ischemic stroke. Having multiple injuries increases that risk, even more so than the severity of a single traumatic brain injury, researchers have found.

New research finds that cerebrospinal fluid net flow is markedly decreased in Huntington’s disease, with the decrease being greater in the later stages of the disease.

The targeted use of ultrasound technology can bring about significant changes in brain function that could pave the way towards treatment of conditions such as depression, addiction, or anxiety, a new study suggests.

Finally this week, new research finds that antidepressants may actually reduce negative memories in individuals suffering from depression while improving overall memory function.