Weekly Neuroscience Update

Credit: Brain Communications (2025)

The parts of the brain that are needed to remember words, and how these are affected by a common form of epilepsy, have been identified by a team of neurologists and neurosurgeons.

New research published in PLOS ONE, reveals that witnessing trauma triggers unique brain changes, distinct from those caused by experiencing trauma firsthand. The study is the first to shed light on the molecular differences between directly acquired PTSD and bystander PTSD and could pave the way for changes in how the disorders are treated.

Scientists have discovered that neural changes in teens may predict how decision-making and behavioural control develop.

A new study shows that the rubber hand illusion can reduce the intensity of pain caused by heat. Researchers found that when participants viewed a rubber hand being illuminated while their hidden hand received a heat stimulus, they reported feeling less pain. This suggests that integrating visual and sensory cues can influence pain perception. The findings may one day help develop new treatments for chronic pain conditions such as complex regional pain syndrome.

Verbal fluency, the ability to recall and use vocabulary, is the strongest cognitive predictor of longevity in a 20-year study of elderly adults. This suggests a link between linguistic ability and overall health.

Neuroscientists have discovered a way to control how much zinc is released to specific locations in the brain. The essential mineral plays a major role in the brain’s function, including improving memory and lessening symptoms of some neurological disorders, but getting the right amount to the right place is key.

According to new research, inflammation inside and outside the brain may contribute to neurological complications in COVID-19.

A study published  in the British Journal of Psychiatry has found that nearly half of people diagnosed with depression don’t respond to multiple antidepressant medications and are considered “treatment-resistant.” The study found that 48% of patients whose electronic health care records reported a diagnosis of depression had tried at least two antidepressants, and 37% had tried four or more different options.

Scientists have developed a computational framework that maps how the brain processes speech during real-world conversations.

For children with autism who severely injure themselves, a pilot study suggests that deep brain stimulation (DBS) of the brain’s reward centre (nucleus accumbens) is a safe and possible treatment that could be beneficial, especially when behavioural therapies don’t work.

New research suggests that factors present in the placenta during pregnancy might play a role in increasing the risk of a child developing schizophrenia.

Scientists at Peking University have used a new method to discover that dopamine helps protect and control the function of a protein called Tau. This finding helps us better understand how dopamine works normally and in diseases of the brain.

A research team has uncovered the neural mechanisms underlying the processing of pain and itch in the anterior cingulate cortex (ACC).

A new study finds that women in their 80s who develop increasing daytime sleepiness over five years are twice as likely to develop dementia. Researchers tracked 733 women without cognitive impairment, using wrist devices to monitor sleep and circadian rhythms. Those who showed stable sleep patterns had the lowest dementia risk, while those with increasing sleepiness faced the highest risk. Surprisingly, declining nighttime sleep was not significantly linked to dementia risk.

A research team has developed an electrode capable of safely encasing nerves without causing damage.

Finally this week, new research shows that even 12-month-old babies can form memories, as indicated by activity in the hippocampus. This challenges the idea that infants can’t remember and suggests that infantile amnesia (not remembering early childhood) might be because we can’t access those memories later, rather than not forming them in the first place.

Weekly Neuroscience Update

Cortical Resting-State Networks defined by Gordon’s Parcellation. Credit: Journal of the American Academy of Child & Adolescent Psychiatry (2025).

Exposure to high ambient temperatures is associated with lower connectivity in three brain networks in preadolescents, suggesting that heat may impact brain function. 

A new study reveals that consuming high-calorie, highly processed foods for just five days can reduce the brain’s sensitivity to insulin, a key factor in obesity and type 2 diabetes. Researchers found that even in healthy individuals, short-term unhealthy eating altered brain function, mimicking effects seen in people with obesity.

Scientists are exploring the role of gut-brain axis in Parkinson’s, anxiety and long COVID.

New research highlights that optimal brain health is strongly linked to cardiovascular wellness. The study underscores that dementia and cognitive decline share risk factors with heart disease, suggesting these conditions are largely preventable by managing diet, exercise, cholesterol, blood sugar, and blood pressure.

Approximately 40 percent of adults with chronic pain experience depression or anxiety, according to a review published in JAMA Network Open.

A multidisciplinary team of researchers has discovered how lateral inhibition helps our brains process visual information, and it could expand our knowledge of sensory perception, leading to applications in neuro-medicine and artificial intelligence.

Brain changes may remain visible in brain scans after recovery from concussion, a new study shows.

Researchers are using photoacoustic imaging to observe brain activity and, in the process, discovering more about how it responds to different types of learning and experiences. Photoacoustic imaging uses optics and acoustics to generate a signal in biological tissues—in this case, the brain—where the signal provides structural and functional data and allows researchers to track factors such as brain activity. 

A study exploring a new brain imaging technique is bringing stroke experts a step closer to better tailoring rehabilitation.

Scientists have uncovered new insights into how neurofilaments act like Velcro in neurodegenerative diseases, clogging up the brain and preventing normal function, according to a study published in the journal JCI Insight.

Poor sleep could have an impact on brain health, according to a new study from The Australian National University (ANU) published in the journal Sleep Medicine.

Mayo Clinic researchers have found a new way to more precisely detect and monitor brain cell activity during deep brain stimulation, a common treatment for movement disorders such as Parkinson’s disease and tremor. This precision may help doctors adjust electrode placement and stimulation in real time, providing better, more personalized care for patients receiving the surgical procedure.

A new neuroimaging study has revealed that viewing nature can help ease how people experience pain, by reducing the brain activity linked to pain perception.

An international team of scientists has revealed new clues about the neural mechanisms underlying memory formation and recognition in the developing human brain, according to a study published in Science Advances.

Poor sleep among older adults is linked to disruptions in the brain’s “waste removal system,” according to a recent study.

Research published in the Proceedings of the National Academy of Sciences  reveals that brain aging isn’t a steady decline, but rather a series of shifts with key turning points. These transition points follow an S-shaped statistical curve with clear transition points, rather than either the late-life clinical onset or gradual linear decline previously assumed, suggesting there are specific windows when intervention could be most impactful.

Finally this week, new research reveals that our brains simplify complex social interactions by using basic mental “building blocks” or shortcuts.

Weekly Neuroscience Update

Credit: Journal of Alzheimer’s Disease (2025). DOI: 10.1177/13872877251319742

Researchers have developed an AI tool that analyzes brain wave activity recorded during sleep using electroencephalography (EEG), a non-invasive technique that measures electrical activity in the brain through sensors placed on the scalp.

An encoding study reveals how the brain uses past experiences to predict the unfolding of similar events over time.

A new brain-computer interface (BCI) has enabled a paralyzed man to control a robotic arm by simply imagining movements. Unlike previous BCIs, which lasted only a few days, this AI-enhanced device worked reliably for seven months. The AI model adapts to natural shifts in brain activity, maintaining accuracy over time.

Learning to think more about specific events in the future appears to reduce impulsivity, improve decision-making, and shows potential as a therapy for alcohol use disorder, a recent study has found.

Repeated sessions of electrical stimulation to brain networks associated with memory improved verbal learning in some Alzheimer’s disease patients for up to eight weeks in a preliminary trial led by UT Southwestern Medical Center researchers. The findings, published in The Journal of Prevention of Alzheimer’s Disease, indicate that while future trials are needed, neurostimulation shows early promise as a treatment for Alzheimer’s and other neurodegenerative disorders, such as Lewy body dementia.

Alcohol use leads to earlier brain aging and impaired behavioral flexibility, with those effects detectable even among adults in their 20s and 30s, according to an innovative study.

Researchers at Karolinska Institutet have identified a new mechanism that may improve the treatment of ischemic stroke. The study, published in the Journal of Clinical Investigation, shows that the growth factor PDGF-CC and its receptor PDGFRα play a crucial role in scar formation in the brain after an ischemic stroke.

An abnormal form of the tau protein found to accumulate in the brains of Alzheimer’s disease patients also accumulates in the eyes of patients with the condition, according to a recent study.

Scientists have observed for the first time how neurons in the human brain store memories independent of the context in which they are acquired. Published in Cell Reports, the study confirms that neurons can distinguish objects or people regardless of their context, enabling the formation of higher and more abstract relationships, which constitute the basis of human intelligence.

Higher fish consumption is associated with slower disability progression in multiple sclerosis (MS), according to research published in the Journal of Neurology, Neurosurgery & Psychiatry.

Using sophisticated neuroimaging techniques, researchers have mapped the brain’s activity during natural conversations, revealing how we seamlessly process speech and sound. These insights not only deepen our understanding of human connection but also pave the way for transformative advancements in speech technology and communication tools.

Finally this week, a recent study in Computers in Human Behavior, researchers observed that staying away from smartphones can even change one’s brain chemistry.

Weekly Neuroscience Update

A global research collaboration has revealed how certain gut cells switch on pain signals, which can linger long after the initial trigger has passed, potentially contributing to chronic pain in conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).

Researchers have identified specific neuronal cells that are essential to our understanding of other people.

A new study reveals that older adults experience the least attention difficulties when home temperatures remain between 68–75 ˚F (20–24 ˚C). Deviations beyond this range double the risk of attention lapses, highlighting how even current climate conditions may harm cognitive health. This risk is especially pronounced for low-income seniors who may lack the means to regulate indoor temperatures.

How the brain feels about the world around it is the subject of a new paper published in Proceedings of the National Academy of Sciences.

Striking brain similarities have been found in patients with long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), in particular, a larger than normal hippocampus. The research also reported the hippocampal volume was associated with symptom severity in both patient groups.

A recent study suggests that first-time transient ischemic attacks (TIA) are associated with long-term cognitive decline.

A new international and multidisciplinary study has unveiled a novel framework for understanding the concept of time persistence in the human brain, shedding light on its essential role in brain functioning and cognition. This research, which explores how long the brain’s functional networks remain in a particular state before transitioning to another, opens new doors to our understanding of human cognition and behavior.

Stress hormones shift neuron types in the developing brain, a new study suggests.

Researchers have developed a new method for deep brain stimulation. The technique, called “DeepFocus,” uses transcranial electrical stimulation (TES) on the scalp and transnasal electrical stimulation (TnES) to achieve more accurate electrical stimulation in the brain.

A new study has found that a short-term, high-caloric diet impairs brain insulin responsiveness and increases liver fat in healthy-weight men, with effects extending beyond the consumption period.

Even when within the normal range, lower levels of vitamin B12 may contribute to cognitive decline, according to a new study that found that older adults with lower biologically active B12 had slower cognitive processing and more white matter.

Researchers have developed an AI that accelerates the identification of genes that contribute to neurodevelopmental conditions such as autism spectrum disorder, epilepsy and developmental delay.

A new study based on data from 18,740 dementia patients suggests that antidepressants may accelerate cognitive decline. Researchers found that patients taking antidepressants, particularly SSRIs like escitalopram, citalopram, and sertraline, experienced faster deterioration compared to those not on medication.

A decade-long study reveals how childhood adversity alters brain development, increasing risks for mental health disorders and substance use. 

The brain may play a role in helping the ear regulate its sensitivity to sound and compensate for hearing loss by sending a signal to a structure in the inner ear known as the cochlea, according to a study that was published in the Journal of Neuroscience.

The symptoms of schizophrenia vary greatly from person to person. A recent study shows how these differences manifest themselves in the structure of the brain.

Researchers have discovered a fundamental mechanism that affects the size of the pupil, namely our breathing. The study, published in the Journal of Physiology, shows that the pupil is smallest during inhalation and largest during exhalation—something that could affect our vision.

Finally this week, a large study found that people who engage in moderate to vigorous physical activity are less likely to develop dementia, stroke, anxiety, depression, and sleep disorders.

Weekly Neuroscience Update

Functional connectivity with the rFP (green, left) defines a distributed brain circuit (right) that will encompass coordinates activated by creativity tasks. Credit: Brigham and Women’s Hospital

A new study suggests that different brain regions activated by creative tasks are part of one common brain circuit. By evaluating data from 857 participants across 36 fMRI studies, researchers identified a brain circuit for creativity and found people with brain injuries or neurodegenerative diseases that affect this circuit may have increased creativity.

New research has uncovered why males and females may experience stress differently, providing insights into how the brain’s molecular mechanisms adapt to acute challenges.

How can nerve pathways in the brain be visualized to improve the planning of complex surgeries? A research team has investigated an AI-powered method that makes these reconstructions more precise. The study, recently published in NeuroImage: Clinical, could ultimately help make neurosurgical procedures safer.

Three studies at the University of Zurich demonstrate that hypnosis alters activity in the large-scale functional networks of the brain. It also affects the neurochemical milieu of specific brain areas.

New research reveals that brain cells use a muscle-like signaling mechanism to relay information over long distances. Scientists discovered that dendrites, the branch-like extensions of neurons, contain a structured network of contact sites that amplify calcium signals—similar to how muscles contract. These contact sites regulate calcium release, activating key proteins involved in learning and memory.

Researchers have made a major breakthrough in understanding the link between genetics and cognition.

A recent large-scale study published in Science Advances has revealed a connection between genetic variations associated with dyslexia and structural differences in the brain. These differences were found in areas involved in motor coordination, vision, and language. This provides new insights into the neurological underpinnings of this common learning difficulty.

According to a recent study, a diet low in vegetables and fruits and high in red meat, fast food, and sugar-sweetened soft drinks was associated with accelerated biological aging.

A new mathematical model sheds light on how the brain processes different cues, such as sights and sounds, during decision making. The findings may one day improve how brain circuits go awry in neurological disorders, such as Alzheimer’s, and could help artificial brains, like Alexa or self-driving car technology, more helpful.

New research has shown just one 20-minute session of moderate intensity aerobic exercise can improve an athlete’s executive function and concussion symptoms in the early stages of recovery.

A recent study using brain imaging technology discovered that experiencing beauty in music involves increased communication between brain areas associated with reward and visual processing, while listening to music considered less beautiful is linked to more activity in brain regions responsible for basic sensory processing. 

Finally this week, women with epilepsy may have offspring with decreased bone metabolism and lower birth weight, according to a study published in the Annals of Clinical and Translational Neurology.

Weekly Neuroscience Update

Schematic representation of the “Harmonic Oscillator Recurrent Network Model” (HORN). Credit: ESI

Researchers have made a new discovery in understanding fundamental brain processes. For the first time, the team has provided compelling evidence that the brain’s characteristic rhythmic patterns play a crucial role in information processing. While these oscillatory dynamics have long been observed in the brain, their purpose has remained mostly elusive until now.

Music has the best chance of providing pain relief when it is played at our natural rhythm, a McGill University research team has discovered.

Tiny plastic particles may accumulate at higher levels in the human brain than in the kidney and liver, with greater concentrations detected in postmortem samples from 2024 than in those from 2016, suggests a paper published in Nature Medicine. Although the potential implications for human health remain unclear, these findings may highlight a consequence of rising global concentrations of environmental plastics.

The first-ever ethics checklist developed for portable MRI brain researchers.

A team of scientists from the Center for Neuroscience Imaging Research (CNIR) at the Institute for Basic Science (IBS) has unveiled how the hippocampus orchestrates multiple memory processes, including encoding new information, forming memories, and retrieving them. The study is published in Nature Communications.

A recent study suggests that frequent treatment with intranasal oxytocin a hormone linked to empathy, may help address a key symptom in patients with frontotemporal dementia.

Researchers using intracranial electroencephalogram (EEG) recordings from deep within the brain found that meditation led to changes in activity in the amygdala and hippocampus, key brain regions involved in emotional regulation and memory.

Could the key to easing anxiety be hidden in our gut? Scientists have discovered a crucial connection between gut microbes and anxiety-related behaviour.

People’s ability to interpret emotions or focus on performing a task is reduced by short-term exposure to particulate matter air pollution, potentially making everyday activities more challenging, according to a new study.

New research has revealed clear evidence that changes in the orchestration of brain oxygenation dynamics and neuronal function in Alzheimer’s disease contribute to the neurodegeneration.

Researchers are paving the way for the design of bionic limbs that feel natural to users. They demonstrate the connection between hand movement patterns and motoneuron control patterns. The study, published in Science Robotics, also reports the application of these findings to a soft prosthetic hand, which was successfully tested by individuals with physical impairments.

Occupational exposure to noise and/or vibrations is associated with the presence of vertigo, according to a study recently published in the Journal of Clinical Medicine.

A team of researchers recently carried out a study aimed at exploring the differences among patients with OCD. Their findings, published in Translational Psychiatry, allowed them to identify two broad OCD subtypes, which are associated with different patterns in gray matter volumes and disease epicenters.

A Canadian research team has revealed important new insights into the activation dynamics of neural stem cells (NSCs). These are the stem cells that build our central nervous systems and self-renew.

New research reveals that brain cells use a muscle-like signaling mechanism to relay information over long distances. Scientists discovered that dendrites, the branch-like extensions of neurons, contain a structured network of contact sites that amplify calcium signals—similar to how muscles contract. These contact sites regulate calcium release, activating key proteins involved in learning and memory.

Finally this week, a large study has found that heavy cannabis use, both recent and lifetime, is linked to reduced brain activity during working memory tasks in over 1,000 young adults.

Weekly Neuroscience Update

Scientists have highlighted the most effective treatments for neurological diseases by overcoming one of medicine’s most difficult challenges: the blood–brain barrier. The findings offer new hope for patients with conditions including Alzheimer’s, and Parkinson’s disease, brain tumors, and epilepsy.

A study conducted in Finland showed that changes in the functioning of opioid neurotransmitters in the brain may underlie anorexia.

Poorer cardiovascular health in childhood and adolescence may be linked to early differences in brain structure, particularly in areas of the brain known to be affected in dementia in later life, according to a new scientific study.

Researchers have uncovered how specific patterns in brain activity can predict an individual’s sensitivity to pain, expanding opportunities for improved pain management strategies.

Delayed rapid eye movement (REM) sleep may be an early indicator of Alzheimer’s disease. Researchers found that participants with delayed REM sleep had higher levels of toxic proteins associated with Alzheimer’s and reduced levels of brain-derived neurotrophic factor (BDNF), which supports memory.

The microbial ecosystems in our mouths may impact cognitive function as we age, with pathogenic bacteria linked to cognitive decline.

New research suggests that mood swings in bipolar disorder are regulated by two clocks: the body’s 24-hour circadian rhythm and a dopamine-based clock that influences alertness. When these clocks align at specific intervals, they may trigger shifts between mania and depression.

A study in the Journal of Neuroscience reveals a new mechanism for how brain cells transmit signals from their tips to their nucleus, triggering gene activation crucial for learning and memory.

Investigators have discovered that activity in two widely distributed brain networks previously considered separate are actually correlated with each other and together play a key role in recognition memory, according to a study published in Cell Reports.

Cannabinoids offer new hope for safe and effective pain relief.

Researchers analyzed the genetic connection of retinal cells and several neuropsychiatric disorders. By combining different datasets, they found that schizophrenia risk genes were associated with specific neurons in the retina. The involved risk genes suggest an impairment of synapse biology, so the ability of neurons to communicate with each other. This impairment might also be present in the brains of schizophrenia patients.

Researchers at the University of Barcelona have identified a deficit in contrast perception in people with schizophrenia.

A study of nearly 1,000 people with post-COVID-19 syndrome (PCS) revealed that two-thirds still experienced significant symptoms, including reduced exercise capacity and cognitive performance, two years after infection. Persistent symptom clusters included fatigue, neurocognitive disturbances, and post-exertional malaise, with worse outcomes in individuals with obesity, lower education, or severe initial infections.

Finally this week, new research shows diets high in processed meat, fast food, and sugary drinks accelerate biological aging, even in young adults.

Weekly Neuroscience Update

Cortical gray matter volume trajectories based on the functional location of the changes in gestational mothers (N = 179). Credit: Nature Communications (2025).

A new study has analyzed the brains of women during pregnancy for the first time using neuroimaging techniques. The research shows that there is a reduction and partial recovery of almost 5% of gray matter in 94% of the total gray matter volume of the brain, especially in regions linked to social cognition.

An international team has shown the relationship of activity of neurotransmitters to how humans process the emotional content of language.

More than half of 23-year-olds in a European study show restrictive, emotional or uncontrolled eating behaviours, according to new research led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London. Structural brain differences appear to play a role in the development of these eating habits.

A new framework links brainwaves to individual cognitive states.

In a recent study, scientists have shown neurotransmitters in the human brain are active during the processing of the emotional content of language, providing new understanding into how people interpret the significance of words.

A new study shows stem cell therapy ‘jump-start’ brain repair after stroke.

Researchers have developed a flexible, biodegradable electrode capable of stimulating neural precursor cells in the brain, offering a safer and more precise alternative for neural repair. The electrode dissolves naturally after seven days, eliminating the need for surgical removal while promoting tissue regeneration.

Music supports babies in neonatal intensive care units, according to a recent neuroimaging study.

A study analyzing data from over 130 million individuals found that antibiotics, antivirals, vaccines, and anti-inflammatory medications are associated with a reduced risk of dementia. This supports the idea that infections and inflammation contribute to dementia and highlights the potential of repurposing existing drugs for prevention or treatment.

New research has uncovered psychological profiles associated with mental and brain health in middle-aged and older adults.

An experimental treatment for depression that triggers seizures with magnets significantly improved mental health in patients without some cognitive effects associated with electroconvulsive therapy (ECT), according to a clinical trial led by UT Southwestern Medical Center.

A research team has gathered new insight into the neural underpinnings of human cooperation.

A new study has identified three psychological profiles that influence brain health, cognitive decline, and dementia risk in aging adults. Profiles with high protective traits, like purpose and openness, show better cognition and brain integrity, while those with low protective traits or high negative traits face accelerated brain atrophy and mental health issues.

Stanford Medicine scientists are generating a periodic table of sorts for psychiatric disorders, providing a better understanding of these conditions and paving the way toward targeted treatment.

A study analyzing data from over 2 million veterans found that GLP-1 receptor agonists, popular weight-loss drugs like Ozempic and Wegovy, provide significant neurological and behavioral health benefits, including reduced risks of addiction, Alzheimer’s, and dementia. However, they also pose risks for pancreatitis and kidney conditions.

Finally, this week, a brain signal that lights up when we anticipate rewards may hold the secret to helping people overcome depression, and researchers are working to unlock its potential.

Weekly Neuroscience Update

A new study has shown neurotransmitters in the human brain are released during the processing of the emotional content of language, providing new insights into how people interpret the significance of words.

Researchers have identified how cerebrovascular disease disrupts brain connectivity, contributing to cognitive decline and neurodegeneration alongside Alzheimer’s disease. 

There may be a link between hearing impairment and an increased risk of developing Parkinson’s according to research led by Lancaster University.  Researchers analyzed data from over 159,000 individuals, finding that every 10-decibel increase in hearing loss corresponded to a 57% higher risk of Parkinson’s. While the findings highlight a strong association, the causality between hearing loss and Parkinson’s remains unclear.

A new systematic literature search has identified the highest priority clinical actions aimed at improving post-acute care for non-hospitalized traumatic brain injury.

Researchers are making strides in restoring touch sensations to prosthetic limbs through brain stimulation. By using electrodes in the brain’s touch center, they can evoke stable, precise sensations, even allowing users to feel the shape and motion of objects.

Increasing physical fitness levels has a causal link with better language comprehension, according to the first study to show this effect.

New research reveals that certain cells inactivate one parent’s copy of a gene, leading to a bias in gene activity that may explain why some individuals with disease-causing mutations remain symptom-free. This selective gene inactivation, known as monoallelic expression, affects about 1 in 20 genes and varies between cell types.

A new study from Karolinska Institutet and Mayo Clinic has revealed important insights into brain degeneration in dementia with Lewy bodies.

Tourette syndrome is currently diagnosed about three times more frequently in males than in females. A new study finds that females are less likely to be diagnosed with the syndrome, take longer to receive a diagnosis and are older when they are diagnosed than male individuals.

Finally this week, a new study has found that eating greater quantities of red meat, especially in processed forms, increases the risk for dementia.

Weekly Neuroscience Update

Regional Cortical Volume and Thickness Associations With Early Substance Use Initiation in the Adolescent Brain Cognitive Development (ABCD) Study. Credit: JAMA Network Open (2024). 

A new study has identified neuroanatomical differences in children associated with early substance use initiation.

Vagus nerve stimulation (VNS) shows a positive treatment effect and improved quality of life (QoL) among patients with treatment-resistant depression according to two studies published in Brain Stimulation.

A new analysis of U.S. mortality data reveals the disproportionate impact of traumatic brain injuries on older adults, males and certain racial and ethnic groups.

Gender differences define how the human brain ages and telltale biomarkers in the blood may be strongly suggestive of cognitive impairment and dementia, according to a comprehensive new study involving more than 500 people.

Researchers have identified genetic variations in brain cells, particularly microglia and oligodendrocytes, that influence both aging and Alzheimer’s risk.

New research shows that not all brain cells age equally, with certain cells, such as those in the hypothalamus, experiencing more age-related genetic changes. These changes include reduced activity in neuronal circuitry genes and increased activity in immunity-related genes.

A recent study has found that menopause revs up the progression of multiple sclerosis (MS).

Researchers have discovered that pupil size during non-REM sleep correlates with memory consolidation. When pupils contract, the brain focuses on consolidating new memories; when dilated, it processes older ones. This separation prevents “catastrophic forgetting,” allowing the brain to efficiently manage both new and existing knowledge. These findings could lead to better memory enhancement techniques for humans and inspire more efficient artificial neural networks.

A new study shows head trauma may activate latent viruses, leading to neurodegeneration.

A collaborative effort between Mount Sinai and Memorial Sloan Kettering Cancer Center has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of these monoamines to histone proteins, the core DNA-packaging proteins of our cells.

Finally this week, sex differences in brain structure are present from birth, new research shows.