Why do people experience the same pain differently, and why can the same pain seem worse to a single individual from one day to the next?
Find out the answers in this recent online presentation for the Migraine Association of Ireland.
Weekly Neuroscience Update
Researchers using MRI have found that iron accumulation in the outer layer of the brain is associated with cognitive deterioration in people with Alzheimer’s disease, according to a study published in the journal Radiology.
Examining the brains of frequent cannabis users, researchers have identified a pattern of connectivity related to craving the substance.
Auditory hallucinations, a common feature of psychosis and schizophrenia, may be the result of increased connectivity between sensory and language processing areas in the brain.
Nitrous oxide may provide temporary relief to veterans suffering from PTSD, a new study reports.
Light to moderate weekly alcohol consumption during middle age could help preserve brain function as we get older. Compared to non-drinkers, those who had a drink or two a day tended to have better performance on cognitive tests over time.
Low levels of the stress hormone cortisol and the GLIZ protein can trigger chronic inflammatory responses in the body, contributing to the aging process.
The placentas of sixteen women who contracted COVID-19 during pregnancy showed evidence of significant injury, a new study reports. The placental injuries were consistent with abnormal blood flow between mother and baby in-utero, suggesting another complication of coronavirus infection in pregnant women.
Finally this week, a new study highlights the most common neurological and psychological complications that arise as a result of coronavirus infection.
Weekly Neuroscience Update
New findings suggest humans have a stereo sense of smell that subconsciously guides navigation.
The study of a man with a neurodegenerative disease that has robbed his ability to see certain numbers sheds light on how the brain processes information without any visual awareness of the stimuli.
Young adults who acquire fewer genetic mutations over time lived five years longer than those who acquired them more rapidly.
96% of patients hospitalized for coronavirus infections report experiencing PTSD as a result of their illness. Researchers also found an increased risk of depression, anxiety, and other mental health disorders in those hospitalized for COVID-19.
Genetic deletions associated with neurodevelopmental disorders may also be linked to dysfunctional organ development, a new study reports.
A new study reveals the relationship between attentional state and emotions from pupillary reactions. Visual perception elicits emotions in all attentional state, while auditory perception elicits emotions only when attention is paid to sounds.
Statins lowered the death rate and decreased the need for mechanical ventilation in patients hospitalized for severe COVID-19.
A new study has identified a different set of individual neurons in the medial frontal cortex that is responsible for memory-based decision making. The findings have implications for the treatment of Alzheimer’s disease, schizophrenia, and other disorders associated with problems in cognitive flexibility.
Elevated pulse pressure in blood traveling to the brain causes inflammation, oxidative stress, and apoptosis in the blood-brain barrier that leads to brain damage.
Researchers have found an unexpected set of mental illnesses in patients with a spectrum of a rare genetic disorder. Their study revealed the need for clinicians to consider the complexities of co-existing conditions in patients with both psychological and fragile X associated disorders.
Finally this week, people experience a flattening of emotions following a single night of poor sleep. Researchers also found a link between sleep deprivation, learning, and reaction time.
Weekly Neuroscience Update
Brain regions where symptoms of depression and anxiety were associated with decreased opioid receptor availability. Image is credited to Lauri Nummenmaa
New research reveals how the brain’s opioid system is linked to mood changes associated with depression and anxiety. Neuroimaging revealed, in those with depression, there is a decreased number of opioid receptors in specific areas of the brain.
Chandelier cells have an unusual direct method of communication. Unlike other neurons, chandelier cells connect directly to the part of a target neuron that initiates a spike.
Using optogenetics, researchers were able to manipulate oxytocin producing cells in a highly precise manner. They discovered oxytocin can amplify aggression as well as social friendliness.
Some coronavirus patients exhibit clinical and neurochemical signs of brain injury associated with the viral infection.
When it comes to processing information about motion, neurons in the ventral intraparietal area of the brain are more flexible in switching between reference frames. The findings could be used to develop neural prosthetics designed for motion control.
The suicide rate for people with schizophrenia spectrum disorders (SSD) is 170 times higher than the general population according to a study published in the journal Schizophrenia Research.
Repetitive negative thinking in those aged over 55 is associated with an increased risk of cognitive decline and deposition of proteins associated with Alzheimer’s disease.
Researchers have identified a specific, front-line defense that limits the infection to the olfactory bulb and protects the neurons of the olfactory bulb from damage due to the infection.
A new study offers clues to how neurons can rewire and restore pathways following injury or illness.
Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson’s disease, according to a new study.
Finally this week, a team of researchers has created a new technology that enhances scientists’ ability to communicate with neural cells using light.
Weekly Neuroscience Update
A new review of neurological symptoms of COVID-19 patients reveals the disease poses a global threat to the entire nervous system, reports a study in Annals of Neurology.
Researchers have combined tools from machine learning and neuroscience to discover that the brain uses a mathematical system to organize visual objects according to their principal components.
A new system for high-density EEG helps with the imaging of the origin and path of both normal and abnormal neural activity.
Brain function depends on inhibitory cells that balance or ‘brake’ excitation. These neurons allow the brain to process information and also prevent runaway seizures. A new study however, reports that in some critical structures of the developing brain, the inhibitory neurons cause excitation rather than suppression of brain activity. The findings, published in Science Advances, could have implications for the treatment of neonatal seizures.
New research shows changes in gut mucus may contribute to Alzheimer’s, Parkinson’s, and other neurological disorders.
Researchers have identified how specific genetic mutations cause ALS. The pathway, they believe, may also be responsible for the development of frontotemporal dementia.
Cancer itself, rather than chemotherapy alone, may contribute to the development of neuropathy some patients experience.
Finally this week, results from a new study suggest that whether certain genes are expressed — turned on or off– may play a role in susceptibility to post-traumatic stress disorder (PTSD).
Weekly Neuroscience Update
Image showing a map of the brain surface showing regions that preferentially activate during face (blue) and scene (red) identification. Image is credited to Oscar Woolnough, PhD, postdoctoral research fellow in the Department of Neurosurgery at McGovern Medical School at UTHealth in Houston.
A new study reveals areas of brain where recognition and identification occur.
Researchers have identified a hippocampal neural network that activates during stress. Activity in a hippocampal-hypothalamus network predicts greater feelings of stress, while connectivity between the hippocampus and dorsolateral prefrontal cortex predicts less stress.
Researchers have identified27 protein biomarkers that can predict whether a patient with COVID-19 is likely to develop severe coronavirus symptoms.
While the amount of antibodies generated varies widely in patients who have recovered from coronavirus, most people generate at least some antibodies which are intrinsically capable of neutralizing the SARS-CoV-2 virus according to a new study.
Twenty-nine genes have now been identified as being linked to problematic alcohol use.
Toxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer’s disease. A new study published in Nature Communications shows that the spread of toxic tau in the human brain in elderly individuals may occur via connected neurons. The researchers could see that beta-amyloid facilitates the spread of toxic tau.
Certain personality traits could increase the risk of developing mild cognitive impairment, a new study reports.
The anesthetic drug ketamine has been shown, in low doses, to have a rapid effect on difficult-to-treat depression. Researchers at Karolinska Institutet now report that they have identified a key target for the drug: specific serotonin receptors in the brain. Their findings, which are published in Translational Psychiatry, give hope of new, effective antidepressants.
Finally this week, a new study shows some infants can identify differences in musical tones at six months.
Weekly Neuroscience Update
A new neuroimaging study sheds new light on how we perceive colors. Activity in higher visual cortex areas matched the colors test subjects saw.
New neurostimulation technology works safely and non-invasively to modify brain activity. The findings may provide some foundational knowledge for the development of future technologies that could expedite cognitive processes.
New research has shown that certain presentations of memory concerns by older adults are predictive of future dementia.
A team of researchers has provided compelling evidence of the impact of adversity in childhood on neuropsychological functioning in adulthood. They also showed that neuropsychological difficulties may explain why early adversity is linked to attention deficit hyperactivity disorder (ADHD) in later life.
A new machine-learning algorithm is more accurate at determining personality traits based on selfie photographs than humans are.
Neuroscientists have traced neural pathways that connect the brain to the stomach, providing a biological mechanism to explain how stress can foster ulcer development.
Researchers have identified both genetic and neural mechanisms associated with romantic love and attachment.
The placentas of sixteen women who contracted COVID-19 during pregnancy showed evidence of significant injury, a new study reports. The placental injuries were consistent with abnormal blood flow between mother and baby in-utero, suggesting another complication of coronavirus infection in pregnant women.
Researchers have developed a sniff test that can detect which patients in a vegetative state following a TBI will regain consciousness.
During early childhood, girls with autism tend to show greater reduction and less rise in their autism symptom severity than boys with autism, a new study has found.
Finally this week, a new study reviewing neuroimaging and neurological symptoms in patients with COVID-19 may shed light on the virus’s impact on the central nervous system.
Weekly Neuroscience Update
Drumming in a group stimulates behavioral and physiological synchronization, which contributes to the formation of social bonds and the ability to cooperate.
Caffeine and urate have been associated with a reduced risk of idiopathic Parkinson’s disease. Researchers noted a lower caffeine intake in idiopathic Parkinson’s patients. Increasing caffeine consumption was linked to decreased odds of being diagnosed with Parkinson’s. Lower levels of blood urate were also associated with an increased risk of Parkinson’s disease.
The endogenous compound anandamide—often referred to as the body’s own marijuana—plays a role in erasing memories of a traumatic event.
A recent neuroimaging study reveals the neural basis for the motivation to reunite with the ones you love. The findings could lead to new therapies for disorders associated with social behaviors, and may also help explain why social distancing is so tough.
Researchers have identified a new, early biomarker for amyotrophic lateral sclerosis (ALS) on the teeth of children.
Following a one year program of aerobic exercise improves memory function and boosts blood flow to brain areas critical for cognition in older adults with risk factors for dementia.
A new blood test can help predict which patients with multiple sclerosis will see a decline in their condition over 12 months.
In late-stage multiple sclerosis, inflammatory cells no longer enter the brain via the bloodstream, but instead the cells arise in memory from local memory cells inside the brain. The findings suggest during the late phases of multiple sclerosis, the disease is occurring entirely inside the brain.
Women who take oral birth control pills have higher levels of oxytocin than women who don’t use the pill.
Researchers have uncovered the process by which air pollution can damage brain cells, leading to an increased risk of Parkinson’s disease. Chemicals found in diesel fuel reduced autophagic flux, which is a major pathway implicated in neurodegeneration.
Finally this week, new evidence suggests the brain can update poorly formed memories with incorrect information, leading to the creation of false memories.
Weekly Neuroscience Update
It’s never too late to lace up your sneakers for brain health, according to a study published in the May 13, 2020, online issue of Neurology. The study suggests older adults, even couch potatoes, may perform better on certain thinking and memory tests after just six months of aerobic exercise.
A new case study reveals a link between COVID-19 and clotting in blood vessels in the brain that results in an increased risk of ischemic stroke.
Rhythm begins in the womb and the heartbeat. And recent findings in neuroscience reveal that for the rest of our lives, rhythm will continue to have a fundamental impact on our ability to walk, talk — and even love.
Researchers studying the structure of the virus that causes COVID-19 have found a unique feature that could explain why it is so transmissible between people.
Recovered coronavirus patients show a wide range of immune responses following the infection, with about half from a current study showing sustained antibodies two weeks later. Results indicate which parts of the virus are most effective at triggering the immune responses.
Neuroscientists have identified memory cells that help us interpret new situations.
The strength of a person’s mental imagery is associated with excitability in the prefrontal cortex and visual cortex. Highly excitable neurons in the visual cortex may reduce a person’s ability to imagine mental images.
Finally this week, after studying global data from the COVID-19 pandemic, researchers have discovered a strong correlation between severe vitamin D deficiency and mortality rates.
Weekly Neuroscience Update
In a new study, researchers identified the most common characteristics of 85 COVID-19 patients who died in Wuhan, China in the early stages of the coronavirus pandemic. The study reports on commonalities of the largest group of coronavirus patient deaths to be studied to date.
Abnormal blood clotting contributes to death in some patients with severe COVID-19 infections.
A newly developed blood test for Alzheimer’s disease measures a specific variant of the tau protein. Early results show the test has a good capacity to distinguish Alzheimer’s disease from other tauopathies.
New findings support the theory that impaired prefrontal control of the dopamine system is a key mechanism for the development of schizophrenia.
Researchers report that in depressed individuals there are increased amounts of an unmodified structural protein, called tubulin, in lipid rafts — fatty sections of a cell membrane — compared with non-depressed individuals.
A new genetics test for COVID-19 has been developed by an international team of researchers.
Genetic variability in the human immune system may affect susceptibility to, and severity of infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for the coronavirus disease (COVID-19).
Researchers have developed a new approach to prevent amyloid plaque formation by engineering a nanodevice that captures the peptides before they can assemble.
A new study puts into question conventional belief that the eyes communicate with the brain exclusively via one signaling pathway. Researchers have identified a subset of retinal neurons that sends inhibitory signals to the brain. This subset of neurons is also involved in the synchronization of circadian rhythms to light/dark cycles and pupil constriction to bright light intensity.
Finally, this week, a new study sheds light on the role brain insulin plays in weight and visceral fat accumulation.
