Weekly Neuroscience Update

Loneliness? It’s All a State of Mind

Researchers have found that lonely people have less grey matter in a part of the brain associated with decoding eye gaze and other social cues.

While studying the sense of touch, scientists at Duke Medicine have pinpointed specific neurons that appear to regulate perception.

An international team of researchers has for the first time shown that one area of the brain, called the anterior insular cortex, is the activity center of human empathy, whereas other areas of the brain are not.

Early surgery for patients with slow-growing, low-grade glioma brain tumours may result in better survival than a wait-and-see approach, according to Norwegian research.

Books and educational toys can make a child smarter, but they also influence how the brain grows, according to new research. The findings point to a “sensitive period” early in life during which the developing brain is strongly influenced by environmental factors.

Exercising in your 70s may stop your brain from shrinking and showing the signs of ageing linked to dementia, say experts from Edinburgh University.

A patient’s genetic makeup may explain the “placebo effect,” in which people perceive that a fake treatment makes them feel better, according to a study that may help researchers design better clinical trials. Patients with a certain variation on a gene linked to release of dopamine, a brain chemical that affects emotions and sensations of pleasure and pain, were more likely to respond to a placebo version of acupuncture than patients with a different variation, a study in the journal PLoS One found.

UCLA researchers have for the first time measured the activity of a brain region known to be involved in learning, memory and Alzheimer’s disease during sleep. They discovered that this part of the brain behaves as if it’s remembering something, even under anesthesia, a finding that counters conventional theories about memory consolidation during sleep.

The brains of teenage girls with behavioural disorders are different to those of their peers, UK researchers have found. The Journal of Child Psychology and Psychiatry study of 40 girls revealed differences in the structure of areas linked to empathy and emotions. Previous work has found similar results in boys.

There are two ways we can forget a memory that causes unpleasant sensations, be they a humiliating gaffe at some dinner party or an extremely frightening event, say researchers from the University of Cambridge in the October 17th edition of Neuron.

Weekly Neuroscience News

An early childhood surrounded by books and educational toys will leave positive fingerprints on a person’s brain well into their late teens, a two-decade-long research study has shown.

Dopamine is a neurotransmitter that is associated with emotions, movement, and the brain’s pleasure and reward system. In the current issue of Advances in Neuroimmune Biology, investigators provide a broad overview of the direct and indirect role of dopamine in modulating the immune system and discuss how recent research has opened up new possibilities for treating diseases such as Parkinson’s and Alzheimer’s disease, schizophrenia, multiple sclerosis or even the autoimmune disorders.

Studies released this week explore the neurological component of dietary disorders, uncovering evidence that the brain’s biological mechanisms may contribute to significant public health challenges — obesity, diabetes, binge eating, and the allure of the high-calorie meal.

By peering into students’ brains, a recent study, published in the journal NeuroImage, found that learning languages can help bulk up the brain.

Research is helping reveal how human and primate brains process and interpret facial expressions, and the role of facial mimicry in everything from deciphering an unclear smile to establishing relationships of power and status.

Neuroscientists from New York University and the University of California, Irvine have isolated the “when” and “where” of molecular activity that occurs in the formation of short-, intermediate-, and long-term memories. Their findings, which appear in the journal the Proceedings of the National Academy of Sciences, offer new insights into the molecular architecture of memory formation and, with it, a better roadmap for developing therapeutic interventions for related afflictions.

An inexpensive, five-minute eye scan can accurately assess the amount of brain damage in people with the debilitating autoimmune disorder multiple sclerosis (MS), and offer clues about how quickly the disease is progressing, according to results of two Johns Hopkins studies.

Weekly Neuroscience Update

Neuroscientists have announced a longitudinal research collaboration to investigate the emotional, social and cognitive effects of musical training on childhood brain development. The five-year research project, Effects of Early Childhood Musical Training on Brain and Cognitive Development, will offer USC researchers an important opportunity to provide new insights and add rigorous data to an emerging discussion about the role of early music engagement in learning and brain function.

UCLA researchers have for the first time measured the activity of a brain region known to be involved in learning, memory and Alzheimer’s disease during sleep. They discovered that this part of the brain behaves as if it’s remembering something, even under anesthesia, a finding that counters conventional theories about memory consolidation during sleep.

New research reveals that stroke may be affecting people at a younger age. The study is published in the October 10, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

Scientists studying a rare genetic disorder have identified a molecular pathway that may play a role in schizophrenia, according to new research in the October 10 issue of The Journal of Neuroscience. The findings may one day guide researchers to new treatment options for people with schizophrenia — a devastating disease that affects approximately 1 percent of the world’s population.

Researchers from the University of Exeter Medical School have for the first time identified the mechanism that protects us from developing uncontrollable fear.

Small amounts of the drug ketamine can immediately relieve the symptoms of chronic depression, as well as those of treatment-resistant patients within a few hours, say Yale scientists.

Scientists find that competition between two brain regions influences the ability to make healthy choices.

A compassion-based meditation program can significantly improve a person’s ability to read the facial expressions of others, finds a study published by Social Cognitive and Affective Neuroscience. This boost in empathic accuracy was detected through both behavioral testing of the study participants and through functional magnetic resonance imaging (fMRI) scans of their brain activity.

A study in PLOS ONE shows that whether or not you like the person you’re watching can actually have an effect on brain activity related to motor actions and lead to “differential processing” – for example, thinking the person you dislike is moving more slowly than they actually are.

Weekly Neuroscience Update

An aspirin a day may slow brain decline in elderly women at high risk of cardiovascular disease, research finds.

The hippocampus represents an important brain structure for learning. Scientists at the Max Planck Institute of Psychiatry in Munich discovered how it filters electrical neuronal signals through an input and output control, thus regulating learning and memory processes.

Scientists performing experimental brain surgery on a man aged 50 have stumbled across a mechanism that could unlock how memory works. The accidental breakthrough came during an experiment originally intended to suppress the obese man’s appetite, using the increasingly successful technique of deep-brain stimulation. Electrodes were pushed into the man’s brain and stimulated with an electric current. Instead of losing appetite, the patient instead had an intense experience of déjà vu. He recalled, in intricate detail, a scene from 30 years earlier. More tests showed his ability to learn was dramatically improved when the current was switched on and his brain stimulated.

Brain metastases are common secondary complications of other types of cancer, particularly lung, breast and skin cancer. The body’s own immune response in the brain is rendered powerless in the fight against these metastases by inflammatory reactions. Researchers in Vienna have now, for the first time, precisely characterised the brain’s immune response to infiltrating metastases. This could pave the way to the development of new, less aggressive treatment options.

Weekly Neuroscience Update

Have you ever wondered why some people find it so much easier to stop smoking than others? New research shows that vulnerability to smoking addiction is shaped by our genes. A study from the Montreal Neurological Institute and Hospital — The Neuro, McGill University shows that people with genetically fast nicotine metabolism have a significantly greater brain response to smoking cues than those with slow nicotine metabolism.

When children learn to play a musical instrument, they strengthen a range of auditory skills. Recent studies suggest that these benefits extend all through life, at least for those who continue to be engaged with music. But a study published last month is the first to show that music lessons in childhood may lead to changes in the brain that persist years after the lessons stop.

A team of Australian researchers, led by University of Melbourne has developed a genetic test that is able to predict the risk of developing autism spectrum disorder (ASD).

Recent findings by an international collaboration including IRCM researchers hold new implications for the pathogenesis of myotonic dystrophy.

Researchers at Newcastle University have revealed the mechanism by which neurons, the nerve cells in the brain and other parts of the body, age. The research opens up new avenues of understanding for conditions where the ageing of neurons are known to be responsible, such as dementia and Parkinson’s disease.
Finally, this week…a new study has shown that it’s possible to predict how well people will remember information by monitoring their brain activity while they study.

Weekly Neuroscience Update

New research from Weizmann Institute, published in Nature Neuroscience has discovered that people can actually learn during sleep, which can unconsciously modify their behavior while awake.

Studies have shown that listening to music can soothe hospital patients, improve stroke outcomes and promote the releaseof the neurotransmitter dopamine in the brain sending pleasure signals throughout the body. Now findings recently presented at the Association for the Scientific Study of Consciousness suggest that playing familiar music could enhance cognitive response among patients with brain damage.

In a major development  Bionic Vision Australia researchers have successfully performed the first implantation of an early prototype bionic eye with 24 electrodes.

Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of subjects, the study broadens understanding of how gene changes may make a child susceptible to this early childhood cancer, as well as causing a tumor to progress.

In a study published in the Journal of Neurology, researchers claim that because Attention Deficit Hyperactivity Disorder (ADHD), Fetal Alcohol Spectrum Disorder (FASD) and Parkinson’s Disease (PD) each involve ocular control and attention dysfunctions, they can be easily identified through an evaluation of how patients move their eyes while they watch television.

A new study by researchers at NYU School of Medicine reveals for the first time that metabolic syndrome (MetS) is associated with cognitive and brain impairments in adolescents and calls for pediatricians to take this into account when considering the early treatment of childhood obesity.

People whose blood sugar is on the high end of the normal range may be at greater risk of brain shrinkage that occurs with aging and diseases such as dementia, according to new research published in the September 4, 2012, print issue of Neurology®, the medical journal of the American Academy of Neurology.

Weekly Neuroscience Update

We already known that bright light therapy can be an effective cure for seasonal depression, but a new study from Finnish University students has revealed that it also benefits those not struggling from seasonal depression at all. When the therapy is administered through the ear canal directly to the photosensitive brain tissue, it not only improves the cognitive performance and mood of those with the depression, but those without it as well.

Recent studies using brain scans have found that the areas of the brain associated with mood, conscious thought and concentration are hyperconnected in people with depression.

Researchers have pinpointed the area of the brain responsible for gullibility and have theorized why it makes children, teens and seniors less likely to doubt.

The human brain is wired to remember emotionally charged events while discarding mundane information like where you left your car keys, Canadian scientists say. Emotional or traumatic events, like special occasions or accidents, are interpreted more keenly by our brains and stored with greater coherence.

Researchers at the University of Southern California have devised a method for detecting certain neurological disorders through the study of eye movements.

A new study by researchers has found that the strength of communication between the left and right hemispheres of the brain predicts performance on basic arithmetic problems. The findings shed light on the neural basis of human math abilities and suggest a possible route to aiding those who suffer from dyscalculia an inability to understand and manipulate numbers.

Bringing the real world into the brain scanner, researchers can now determine the action a person was planning, mere moments before that action is actually executed. The findings were published this week in the Journal of Neuroscience, in the paper, “Decoding Action Intentions from Preparatory Brain Activity in Human Parieto-Frontal Networks.”

 

Weekly Neuroscience Update

When sound waves hit a sensory cell of the ear, they are converted into electrical nerve signals through specialized ion channels that open and close. Scientists at the University of Göttingen have now discovered a protein that is essential for the opening and closing of these ion channels. The protein could thus be responsible for the ability to hear.

High baseline levels of neuronal activity in the best connected parts of the brain may play an important role in the development of Alzheimer’s disease.

A team of researchers have developed a multidimensional set of brain measurements that, when taken together, can accurately assess a child’s age with 92 percent accuracy.

A mysterious region deep in the human brain could be where we sort through the onslaught of stimuli from the outside world and focus on the information most important to our behavior and survival, Princeton University researchers have found.

Weekly Neuroscience Update

A growing body of evidence suggests that learning to play an instrument and continuing to practice and play it may offer mental benefits throughout life. Hearing has also been shown to be positively affected by making music. The latest study, published in the July issue of Frontiers in Human Neuroscience, shows that musical instrument training may reduce the effects of mental decline associated with aging. The research found that older adults who learned music in childhood and continued to play an instrument for at least 10 years outperformed others in tests of memory and cognitive ability.

Neuroscientists are finding that, as we get older, our aging brains are proving surprisingly malleable, and in ways not previously anticipated. But there are limitations. There is growing evidence that, beyond what was previously believed, the adult human brain is remarkably malleable and capable of new feats — even in the last decades of life. And UCLA researchers found that older adults who regularly used a brain fitness program played on a computer demonstrated significantly improved memory and language skills.

From older to younger brains now…

Determining when a teenage brain becomes an adult brain is not an exact science but it’s getting closer, according to an expert in adolescent developmental psychology, speaking at the American Psychological Association’s 120th Annual Convention.

Researchers at Aalto University in Finland have developed the world’s first device designed for mapping the human brain that combines whole-head magnetoencephalography (MEG) and magnetic resonance imaging (MRI) technology. MEG measures the electrical function and MRI visualizes the structure of the brain. The merging of these two technologies will produce unprecedented accuracy in locating brain electrical activity non-invasively

According to a study conducted by the National Institutes of Health, children with attention-deficit/hyperactivity disorder (ADHD) experience a developmental delay in frontal regions of the brain.

The brain differences found in people with schizophrenia are mainly the result of the disease itself or its treatment, as opposed to being caused by genetic factors, according to a Dutch study

Bilingual children outperform children who speak only one language in problem-solving skills and creative thinking, according to research led at the University of Strathclyde.

When we focus intently on one task, we often fail to see other things in plain sight – a phenomenon known as ‘inattention blindness’. Scientists already know that performing a task involving high information load – a ‘high load’ task – reduces our visual cortex response to incoming stimuli. Now researchers from UCL have examined the brain mechanisms behind this, further explaining why our brain becomes ‘blind’ under high load.

Weekly Neuroscience Update

Two powerful brain chemical systems work together to paralyze skeletal muscles during rapid eye movement (REM) sleep, according to new research in The Journal of Neuroscience. The finding may help scientists better understand and treat sleep disorders, including narcolepsy, tooth grinding, and REM sleep behavior disorder.

Raising levels of the neurotransmitter dopamine in the frontal cortex of the brain significantly decreased impulsivity in healthy adults, in a study conducted by researchers at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco.

Neuroscientists have found strong evidence that vivid memory and directly experiencing the real moment can trigger similar brain activation patterns.

Severe psychological and physical neglect produces measurable changes in children’s brains, finds a study led by Boston Children’s Hospital. But the study also suggests that positive interventions can partially reverse these changes.

Scientists at Johns Hopkins have discovered a “scaffolding” protein that holds together multiple elements in a complex system responsible for regulating pain, mental illnesses and other complex neurological problems.