In search of memory

Neuroscientist Eric Kandel was a recipient of the 2000 Nobel Prize for his research on the physiological basis of memory storage in neurons. He shared the prize with Arvid Carlsson and Paul Greengard.

Kandel believes that memory is everything and without it we are nothing. Memory is the glue that binds our mental life together and provides a sense of continuity in our lives.

Kandel’s book on the brain for the general public, In Search of Memory: The Emergence of a New Science of Mind, won both the Los Angeles Times and U.S. National Academy of Science Awards for best book in Science and Technology in 2008. A documentary film based on the book, also entitled In Search of Memory, was released in 2010 to critical acclaim.

Weekly Round Up

How does cigarette addiction affect the brain?

The effects of nicotine upon brain regions involved in addiction mirror those of cocaine, according to new neuroscience research.

Aspirin and other anti-inflammatory drugs taken for pain relief may reduce the effectiveness of anti-depressants such as Prozac, say US researchers.

Moments of absent mindedness such as losing your keys could be the result of tiny parts of the brain taking “naps” to recharge, a study finds.Researchers discovered that contrary to popular opinion the brain is not always entirely asleep or awake but parts of it can go “offline”.

Neuroscientists at the California Institute of Technology and their colleagues have tied the human aversion to losing money to a specific structure in the brain-the amygdala.

Music is not only able to affect your mood — listening to particularly happy or sad music can even change the way we perceive the world, according to researchers from the University of Groningen.

The positive effects of mindfulness meditation on pain and working memory may result from an improved ability to regulate a crucial brain wave called the alpha rhythm. This rhythm is thought to “turn down the volume” on distracting information, which suggests that a key value of meditation may be helping the brain deal with an often-overstimulating world. And in other  mindfulness research – fMRI shows how mindfulness meditation changes the decision making process

 

Weekly Round-Up

Does sleep help you learn? (Image: Big Stock)

In today’s weekly round-up..how memories take better hold during sleep, nature vs nurture, fake it til you make it, the nature of heroism, the pathology of Alzheimer’s, the neuroscience of fear and loathing, and more.

It appears from the latest research that the best way to hold onto a  newly learned poem, card trick or algebra equation may be to take a quick nap, for the brain is better during sleep than during wakefulness at resisting attempts to scramble or corrupt a recent memory. The study, published in Nature Neuroscience, provides new insights into the complex process by which we store and retrieve deliberately acquired information.

Athena Stalk in Your Brain and The Power of Rehearsing Your Future explains that the advice to “fake it til you make it” is backed up by some of the latest findings on the brain.

Interesting article from Jonah Lehrer in the Wall Street Journal on the perennial nature vs nurture debate. And in a similar vein,  is there a gene for heroism or is it down to social or economic factors?  Can neuroscience explain the nature of heroism?

The Neuroscience of Fear and Loathing is an interesting look at this universal emotion. 

Findings from a new study from the University of Haifa shows that people diagnosed as psychopathic have difficulty showing empathy, just like patients who have suffered frontal head injury.

Article in this week’s New York Times on a new brain scan tech­nol­ogy to detect Alzheimer’s pathol­ogy in the brain.

How Perception Reveals Brain Differences explores the ways in which brains differ from one another and the ways in which we owners perceive the world accordingly.

Weekly Round-Up

Do you gesture while you talk? These gestures seem to be important to how we think. They provide a visual clue to our thoughts and, a new theory suggests, may even change our thoughts by grounding them in action.

In  how the brain shops, we have an exploration of the neurons associated with valuing objects, and on a related theme,  A.K. Pradeep’s  Marketing to Women examines how women shop using their instinct.

An interesting study from Dehaene et al. on how reading rewires the brain 

Latest research shows that emotional stress can change brain function. A single exposure to acute stress affected information processing in the cerebellum — the area of the brain responsible for motor control and movement coordination and also involved in learning and memory formation.

Neuroscientists at MIT’s Picower Institute of Learning and Memory have uncovered why relatively minor details of an episode are sometimes inexplicably linked to long-term memories.

Finally, are you feeling a little bored? Well new research suggests that it is not just in your head. Individual differences in sensitivity to reward, for example, are another important factor.

Neuroscience research may help brain injury recovery

New research shows that the way the brain first captures and encodes a situation or event is quite different from how it processes subsequent similar events.

I was interested to read a special report from the Center for Neuro Skills which describes the latest developments into how the brain registers new memory and equally importantly, how it strengthens older memories.

It has been known for years that the so-called NMDA receptor – a  lock on the skin of the nerve cell which is ‘opened’ by a special key – the neurotransmitter glutamate – is involved in new learning and memory.

However this research shows that the way the brain first captures and encodes a situation or event is quite different from how it processes subsequent similar events,  and suggests a whole new NMDA-independent system involving the so-called AMPA receptor – a less powerful type of NMDA receptor –  involved in strengthening older memories.
Why is this so important?   

Well, this new system is known to be critically involved in Alzheimer’s disease and other kinds of brain deficit memory impairment including stroke and head injury.

In fact, you may be interested to know that several drug companies have developed drugs that open the AMPA receptors called ampakines – a class of compounds known to enhance attention span and alertness, and facilitate learning and memory.

Unlike earlier stimulants such as caffeine, methylphenidate (Ritalin), and the amphetamines, ampakines do not seem to have unpleasant, long-lasting side effects such as sleeplessness.

These new memory enhancing drugs will be coming to a pharmacy near you within the next few years!

Don’t forget!