Twenty years ago, Dr. Amit Sood, a Professor of Medicine at Mayo Clinic, came to the U.S. thinking he was coming to the Disneyland of the world. He expected everyone here to be very happy. What he saw surprised and shocked him. In this funny, fast-moving, and deeply insightful talk, Dr. Sood shares his journey over two decades and across two continents, finding a way to help us outsmart our neural predispositions to suffering. In the process, he takes us on a back-stage tour of the human brain and outlines the gist of a structured program he is taking globally to decrease stress and improve focus, resilience, and happiness.