Category Archives: Brain Injury

Weekly Neuroscience Update

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A research team at Northwestern University are studying the connection between memory and sleep, and the possibilities of boosting memory storage while you snooze.

For the first time, scientists have used a new combination of neural imaging methods to discover how the human brain adapts to injury. The research, published in Cerebral Cortex, shows that when one brain area loses functionality, a “back-up” team of secondary brain areas immediately activates, replacing not only the unavailable area but also its confederates.

New research suggests that testing a portion of a person’s saliva gland may be a way to diagnose Parkinson’s disease. The study was released today and will be presented at the American Academy of Neurology’s 65th Annual Meeting in San Diego, March 16 to 23, 2013.

In a promising finding for epileptic patients suffering from persistent seizures known as status epilepticus, researchers have reported that new medication could help halt these devastating seizures.

Tübingen neuroscientists have shown how decision-making processes are influenced by neurons.

EPFL scientists find evidence that psychological wounds inflicted when young leave lasting biological traces—and a predisposition toward violence later in life

The production of new neurons, known as neurogenesis, was found to be induced in the adult normal cortex by the antidepressant fluoxetine, as reported in a study published online last week in Neuropsychopharmacology. This finding highlights the potential neuroprotective response induced by this antidepressant drug. It also lends further support to the thesis that induction of adult neurogenesis in cortex is a relevant prevention/treatment option for neurodegenerative diseases and psychiatric disorders.

photo credit: Toni Blay via photopin cc


Weekly Neuroscience Update

Mind wandering may increase creative thinking, according to a new international study.

Simple mental activity such as reading, writing, playing games and doing puzzles may protect brain health in old age, according to a new study.

Reduced production of myelin, a type of protective nerve fiber that is lost in diseases like multiple sclerosis, may also play a role in the development of mental illness, according to researchers at the Graduate School of Biomedical Sciences at Mount Sinai School of Medicine.

A small molecule known to regulate white blood cells has a surprising second role in protecting brain cells from the deleterious effects of stroke, Johns Hopkins researchers report.

Scientists have revealed the minutely detailed pain map of the hand that is contained within our brains, shedding light on how the brain makes us feel discomfort and potentially increasing our understanding of the processes involved in chronic pain.

People with Parkinson’s disease benefit from exercise programs on stationary bicycles, with the greatest effect for those who pedal faster, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA).

A new method to study widespread networks of neurons responsible for our memory has been discovered by scientists from the Max Planck Institute for Biological Cybernetics.

The first study to estimate rates of traumatic brain injury (TBI), without relying on official figures, suggests the worldwide incidence of TBI could be six times higher than previously estimated.

MRI shows changes in the brains of people with post-concussion syndrome (PCS), according to a new study published online in the journal Radiology. Researchers hope the results point the way to improved detection and treatment for the disorder.

photo credit: pamlau.com via photopin cc


Researchers map Phineas Gage’s brain

In 1845, an iron rod pierced railroad construction foreman Phineas Gage’s brain, changing neuroscience forever. Now, more than 150 years later, neuroscientists have created a diagram of Gage’s brain, figuring out just which connections were changed by his accident.

Read the full story here


Neuroscience News

Is Angry Birds keeping your brain healthy?

A new study from the Archives of Neurology says playing brain stimulating games can improve your memory and delay or prevent the onset of Alzheimer’s disease.

A new study suggests hearing metaphors can activate brain regions involved in sensory experience.

Whether you are an athlete, a musician or a stroke patient learning to walk again, practice can make perfect, but more practice may make you more efficient, according to a surprising new University of Colorado Boulder study.

Researchers have found a way to study how our brains assess the behavior – and likely future actions – of others during competitive social interactions. Their study, described in a paper in the Proceedings of the National Academy of Sciences, is the first to use a computational approach to tease out differing patterns of brain activity during these interactions, the researchers report.

A molecular path from our body’s internal clock to cells controlling rest and activity have been revealed.

A new study looks at how our brain processes visual information to prevent collisions.

Can Brain Scans of Young Children Predict Reading Problems?  Brain scientists are studying whether they can predict which young children may struggle with reading, in order to provide early help.

Virtual therapists being developed to treat depression. Scientists at a U.S. university are developing new technologies to treat depression and other disorders — including a mood-detecting smart phone that will call to check up on you.

A new study shows how to boost the power of pain relief without drugs.

Neuroscience could change the face of warfare. Soldiers could have their minds plugged directly into weapons systems, undergo brain scans during recruitment and take courses of neural stimulation to boost their learning, if the armed forces embrace the latest developments in neuroscience to hone the performance of their troops

Brain activity differs when one plays against others. Researchers have found a way to study how our brains assess the behavior – and likely future actions – of others during competitive social interactions. Their study, described in a paper in the Proceedings of the National Academy of Sciences, is the first to use a computational approach to tease out differing patterns of brain activity during these interactions, the researchers report.

Reporting in PLoS Biology, researchers write that they were able to correlate words a person was hearing to specific electrical activity in the brain. Neuroscientist Robert Knight, a co-author of the study, discusses future applications of this research and concerns that it amounts to mental wiretapping.

Brains may be wired for addiction.  Abnormalities in the brain may make some people more likely to become drug addicts, according to scientists at the University of Cambridge.

Patients’ Brains May Adapt to ADHD Medication. New research reveals how the brain appears to adapt to compensate for the effects of long-term ADHD medication, suggesting why ADHD medication is more effective short-term than it is long-term.

A two-year study of high school football players suggests that concussions are likely caused by many hits over time and not from a single blow to the head, as commonly believed.


Typing with brain waves

Fascinating video from the Mayo Clinic on research into communicating via brain waves.


Weekly Round Up

A part of the human brain that’s involved in emotion gets particularly excited at the sight of animals, a new study has shown. The brain structure in question is the amygdala: that almond-shaped, sub-cortical bundle of nuclei that used to be considered the brain’s fear centre, but which is now known to be involved in many aspects of emotional learning.

Studies have shown that ­meditating regularly can help relieve chronic pain, but the neural mechanisms ­underlying the relief were unclear. Now, ­researchers from MIT, Harvard, and Massachusetts General ­Hospital have found a possible explanation.

Men and women differ in the way they anticipate an unpleasant emotional experience, which influences the effectiveness with which that experience is committed to memory according to new research.

New research has contradicted a 40-year-old theory of how the brain controls impulsive behavior

Head trauma may increase the risk of developing schizophrenia, a new study says. The results show people who have suffered from a traumatic brain injury (TBI) are 1.6 times more likely to develop schizophrenia compared with those who have not suffered such an injury.

Researchers from the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital have conducted a study which has found striking brain similarities in bipolar disorder and schizophrenia.

The brains of older people are not slower but rather wiser than young brains, which allows older adults to achieve an equivalent level of performance, according to research undertaken at the University Geriatrics Institute of Montreal by Dr. Oury Monchi and Dr. Ruben Martins of the University of Montreal.

A new study testing alcohol’s effects on brain activity finds that alcohol dulls the brain “signal” that warns people when they are making a mistake, ultimately reducing self control.

Researchers in the Netherlands have been able to shed more light on how combat experiences change the brains of soldiers.

And finally, new research from MIT suggests that there are parts of our brain dedicated to language and only language, a finding that marks a major advance in the search for brain regions specialized for sophisticated mental functions.  And this week,new research makes the case that language is not a key part of thinking about numbers, but the key part, overriding other influences like cultural ones.


Weekly Round Up

Researchers Aim for Direct Brain Control of Prosthetic Arms Credit J. Contreras-Vidal/University of Maryland.

Engineering researchers at four U.S. universities are embarking on a four-year project to design a prosthetic arm that amputees can control directly with their brains and that will allow them to feel what they touch. The researchers have developed a prototype of a device that provides feedback to the wearer’s arm while objects are moved with a prosthetic ‘hand,’ a gripper. The prototype, which incorporates noninvasive monitoring of electrical activity and blood-oxygen levels in the brain, may be incorporated into next-generation prosthetic arms.

Millions of people with severe, treatment-resistant depression could improve their condition by adding an anti-inflammatory drug to their antidepressant medication, a leading consortium of UK researchers in biological psychiatry has reported.

A new study of the brain’s master circadian clock – known as the suprachiasmatic nucleus, or SCN — reveals that a key pattern of rhythmic neural activity begins to decline by middle age.

Vanderbilt University psychologists have found that our visual perception can be contaminated by memories of what we have recently seen, impairing our ability to properly understand and act on what we are currently seeing.

And finally, a new study provides clues about the cellular mechanisms of traumatic brain injury, a signature injury of the wars in Iraq and Afghanistan.


Weekly Round-Up

Transcranial magnetic stimulation can minimize forgetfulness

Memory failure is a common occurrence yet scientists have not reached a consensus as to how it happens. However, according to a new study at Beth Israel Deaconess Medical Center, Transcranial magnetic stimulation (TMS) is able to minimize forgetfulness by disrupting targeted brain regions as they compete between memories.

A new study which will be published in an upcoming issue of Psychological Science, finds changes in brain activity after only five weeks of meditation training.

In an ongoing quest to map the brain, scientists have determined how the brain works to understand others. According to a new study, the brain generates empathy in one manner for those who differ physically and in another method for those who are similar. In a paper published online by Cerebral Cortex, researcher Dr Lisa Aziz-Zadeh, suggests empathy for someone to whom you can directly relate — (for example, because they are experiencing pain in a limb that you possess) — is mostly generated by the intuitive, sensory-motor parts of the brain. However, empathy for someone to whom you cannot directly relate relies more on the rationalizing part of the brain.

The brain holds on to false facts, even after they have been retracted according to a report in Scientific American.

Psychologists have found that thought patterns used to recall the past and imagine the future are strikingly similar. Using functional magnetic resonance imaging to show the brain at work, they have observed the same regions activated in a similar pattern whenever a person remembers an event from the past or imagines himself in a future situation. This challenges long-standing beliefs that thoughts about the future develop exclusively in the frontal lobe.

Many dementia patients being prescribed antipsychotic drugs could be better treated with simple painkillers, say researchers from Kings College, London, and Norway.

Brain damage can cause significant changes in behaviour, such as loss of cognitive skills, but also reveals much about how the nervous system deals with consciousness. New findings reported in the July 2011 issue of Cortex demonstrate how the unconscious brain continues to process information even when the conscious brain is incapacitated.

Years after a single traumatic brain injury (TBI), survivors still show changes in their brains. In a new study, researchers from the Perelman School of Medicine at the University of Pennsylvania suggest that Alzheimer’s disease-like neurodegeneration may be initiated or accelerated following a single traumatic brain injury, even in young adults.


Mapping the Brain

Mapping the Brain, is an exhibition of pictorial stories created by people with an acquired brain injury at the National Rehabilitation Hospital in Dún Laoghaire, Co Dublin.

The objective is to create a series of visual stories using pictures to create the narrative. One of the symptoms of acquired brain injury is that it affects the part of the brain that controls language. This can affect anything from speech, to difficulty with reading and interpreting verbal language.

Their finished work is on show in the Mill Theatre, Dundrum, Dublin 14, from Thursday26 May to June 30th.


Gabrielle Giffords’ neurosurgeon speaks about her surgery

 

G. Michael Lemole Jr., M.D., keynote speaker at Health Journalism 2011

G. Michael Lemole Jr., M.D., chief of neurosurgery at the University of Arizona Department of Surgery and University Medical Center, found himself in the media spotlight after he performed brain surgery on U.S. Rep. Gabrielle Giffords after she sustained a gunshot wound to the head in Tucson on Jan. 8.

As the keynote speaker at Health Journalism 2011, he recounted the treatment of the congresswoman earlier this year and his experience working with the media:

Everyone made a big deal of what we did, but it’s what we do everyday … This is academic medicine at its best

In the operation, Lemole and Martin E. Weinand, M.D., removed part of Gifford’s skull to allow her brain to swell, as well as removing dead brain tissue and skull fragments caused by the bullet.

 ”We basically take part of the skull off and let the swollen brain relax,” explained Lemole. The procedure can relieve pressure on the brain but it can also worsen edema – the build-up of fluid that can cause an “outward herniation.” They also had to remove damaged parts of the brain to “save the good brain underneath.”

The procedure is informed by data gathered during surgery on soldiers injured in the Iraq war, he said. At some point, surgeons will replace the bone or use a prosthetic.

On Jan. 15, Lemole repaired Giffords’ orbital roof fracture through a skull base approach.  The last surgery that Giffords received was a ventriculostomy, which measured intracranial pressure and drained fluid in the brain. He credits the use of growing use of simulation in surgical training for allowing doctors to successfully perform operations like the ventriculostomy. In addition to simulation training, Lemole said the “flawless” EMT response and the multidisciplinary nature of trauma team combined to improve Giffords’ odds.

Lemole supervised the congresswoman’s care until she was released to a Houston rehabilitation hospital on Jan. 21 and during  this time, was available to the media. “We strategized with ourselves, administrators, and with the family. The family asked us to get the correct information out,” he said. Lemole said he chose his words carefully. “I don’t think I gave a rosy account,” he said, describing his careful use of the term “functional recovery” instead of terms like “full recovery” or “back to normal.”

Giffords Progress

Giffords outcome was impossible to predict at the outset of her injury. Generally, the odds of dying from a gunshot wound to the head range from 56 to 94 percent, Lemole said. If the path of the bullets goes through the geographic center of the brain, through the ventricles or through multiples lobes, the prognosis is not good. In Giffords’ case, the bullet did not cross from one side of the brain to the other, but travelled through the left side. The patient’s level of consciousness at admission is another factor -  at the time, Lemole was quoted as saying that Giffords was able to follow simple commands from the doctors.

The Arizona Republic newspaper reports “that she can stand on her own and walk a little but is working to improve her gait.” The use of her right arm and leg “is limited but improving” . Longer sentences frustrate her and she speaks most often in a single word or declarative phrases. She longs to leave the rehab center, repeating “I miss Tucson” and wheeling herself to the doors at the end of the hall to peer out. When that day comes, Giffords told her nurse, she plans to “walk a mountain.”

Sources:

Boston Blog

Health Journalism Blog

The Arizona Republic


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